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108 Possible Causes for Hashimoto's Thyroiditis, HLA-B27, Hypothyroidism, Sausage Toe

  • Turner Syndrome

    In infants, the combination of dysplastic or hypoplastic nails and lymphedema gives a characteristic sausage-like appearance to the fingers and toes.[emedicine.medscape.com] OBJECTIVE: To report the case of an individual with PHP, Turner syndrome and Hashimoto's thyroiditis.[ncbi.nlm.nih.gov] Three girls from that subgroup were euthyroid, 5 had subclinical hypothyroidism, and 3 were diagnosed with overt hypothyroidism.[ncbi.nlm.nih.gov] However, it is becoming increasingly evident that adults with Turner's syndrome are also susceptible to a range of disorders, including osteoporosis, hypothyroidism, and renal[ncbi.nlm.nih.gov]

    Missing: HLA-B27
  • Graves Disease

    Needle aspiration from the nodule yielded evidence of Hashimoto's thyroiditis. The patient also tested strongly positive for antithyroid peroxidase antibodies.[ncbi.nlm.nih.gov] CONCLUSION: Although conversion of Hashimoto's hypothyroidism into Graves' disease is exceptional in pregnancy, pregnant women with autoimmune hypothyroidism should ideally[ncbi.nlm.nih.gov] No convincing evidence exists for a role of molecular mimicry between Yersinia and HLA B27 or other host structures.[doi.org] Autoimmune thyroid diseases (AITDs), mainly include Graves' disease (GD) and Hashimoto's thyroiditis (HT), are probably caused by the aberrant proliferation of B cells.[ncbi.nlm.nih.gov]

    Missing: Sausage Toe
  • Juvenile Rheumatoid Arthritis

    There may have been a swollen, ‘sausage’ shaped toe, when your child was younger that got better on its own; this is known as dactylitis [dak-ti-li-tis].[jia.org.uk] We report a case of a young girl affected by three organ-specific autoimmune disorders, from which type 1 diabetes developed first, then Hashimoto's thyroiditis and juvenile[ncbi.nlm.nih.gov] The boy was small for his age and was found to have hypothyroidism at the age of 18 months; he is currently on thyroxine replacement therapy.[ncbi.nlm.nih.gov] There is significant correlation between ANA seropositivity and HLA-B27, early erosion, response to treatment, uveitis and subcutaneous nodule.[ncbi.nlm.nih.gov]

  • Spondylitic Aortitis

    .- Dactylitis ("Sausage-Like" Toes).- Hydroxyapatite Rheumatism (Calcific Periarthritis).- Low Back Pain.- Chondrocalcinosis.- Hereditary Chondrocalcinosis.- Perthes' Disease[booktopia.com.au] HLA-B27 antigen. Social class.[iritis.org] […] or fingers affected, entire digit usually diffusely swollen - 52% sausage digit or dactylitis Skin: Rash 23% keratoderma blennorrhagica papulosquamous rash most commonly[enotes.tripod.com] Increased prevalence of HLA-B27 in whites or HLA-B7 in blacks supports a genetic predisposition.[msdmanuals.com]

  • IgG4-Related Thyroid Disease

    Approximately half (23/38) of patients had a clinical diagnosis of Hashimoto thyroiditis (HT).[ohsu.pure.elsevier.com] Hypothyroidism has been identified in approximately 30% of cases – though hyperthyroidism can occur.[thyroiduk.org.uk] Diseases with evidence of acquired component (MHCI associations) and autoinflammatory components: Ankylosing Spondylitis Reactive Arthritis Psoriasis Behcet’s Syndrome Uveitis (HLA-B27[doczz.it] Immunoglobulin G4 thyroiditis in a Graves' disease patient with a large goiter developing hypothyroidism.[journals.plos.org]

    Missing: Sausage Toe
  • Psoriatic Arthritis

    Such "sausage" toes or fingers can occur before someone even has joint problems.[health.com] Herein, we report a case of predominantly palmoplantar psoriasis with severe nail involvement, psoriatic arthritis, and autoimmune hypothyroidism after receiving nivolumab[ncbi.nlm.nih.gov] While a number of genes are linked to PsA, the highest predictive value is noted with HLA-B27.[spondylitis.org] 079.83 [ 711.5 ] hyperparathyroidism 252.00 [ 713.0 ] hypersensitivity reaction NEC 995.3 [ 713.6 ] hypogammaglobulinemia (see also Hypogammaglobulinemia) 279.00 [ 713.0 ] hypothyroidism[icd9data.com]

    Missing: Hashimoto's Thyroiditis
  • Alopecia Areata

    In this group of patients, hypothyroidism was the most frequent finding 29 (49%), with Hashimoto thyroiditis being the most common cause(24 [41%]).[ncbi.nlm.nih.gov] Abstract We present a 37 year-old man with HLA-B27 positive ankylosing spondylitis for the last 3 years.[ncbi.nlm.nih.gov] Among the thyroid disorders, hypothyroidism was the most frequent association (14.1%) in our study.[ncbi.nlm.nih.gov] […] of Hashimoto thyroiditis (41% or 24).[medpagetoday.com]

    Missing: Sausage Toe
  • Ankylosing Spondylitis

    ' toe Generalized swelling of fore foot Vasculitis Note: Does not tend to affect foot in sero-negative arthritides Radiographs Bone/periosteal fluffy/'whiskery' proliferation[medical-dictionary.thefreedictionary.com] In detail, the most frequently reported NCGS-associated autoimmune disorder was Hashimoto thyroiditis (29 patients).[dx.doi.org] In literature, although the evidence for association between AS and periodontitis as well as AS and HLA-B27 are there but the association of aggressive periodontitis in HLA-B27[ncbi.nlm.nih.gov] Swelling of entire toes or fingers, resulting in sausage digits, also occurs.[northshore.org]

    Missing: Hypothyroidism
  • Sjogren's Syndrome

    ’s) thyroiditis (inflammation of the thyroid), enlargement of the liver, and inflammation of the pancreas.[britannica.com] Finally, autoimmune thyroid disease (ATD) occurs quiet commonly in the setting of primary SS and subclinical hypothyroidism is the main functional abnormality observed in[ncbi.nlm.nih.gov] The incidence mirrors the prevalence of HLA-B27 seropositivity.[doi.org] SS patients, clinical and laboratory features such as hypergammaglobulinemia, symmetric peripheral neuropathy, and hypothyroidism were significantly associated with HLA-DR3[ncbi.nlm.nih.gov]

    Missing: Sausage Toe
  • Seronegative Arthritis

    toe Generalized swelling of fore foot Vasculitis Note: Does not tend to affect foot in sero-negative arthritides Radiographs Bone/periosteal fluffy/‘whiskery’ proliferation[medical-dictionary.thefreedictionary.com] I have severe RA, Hypothyroid that has turned auto and Addison's Disease.[dailystrength.org] HLA-B27 is present in approximately 6-8 % of the normal population in the Indian subcontinent.[ncbi.nlm.nih.gov] 300,00 mg Intravenous Every 8. week Prednisolone 2.2011 - 2,50 mg Peroral Every day Methotrexate 5.2002 - 10,00 mg Peroral Once a week Comorbidity Hyperlipidemia 4.2011 Hypothyroidism[ncbi.nlm.nih.gov]

    Missing: Hashimoto's Thyroiditis

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