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10 Possible Causes for Hashimoto's Thyroiditis, HLA-B27, Sausage Toe

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  • Juvenile Rheumatoid Arthritis

    We report a case of a young girl affected by three organ-specific autoimmune disorders, from which type 1 diabetes developed first, then Hashimoto's thyroiditis and juvenile[ncbi.nlm.nih.gov] There may have been a swollen, ‘sausage’ shaped toe, when your child was younger that got better on its own; this is known as dactylitis [dak-ti-li-tis].[jia.org.uk] There is significant correlation between ANA seropositivity and HLA-B27, early erosion, response to treatment, uveitis and subcutaneous nodule.[ncbi.nlm.nih.gov]

  • Ankylosing Spondylitis

    ’s thyroiditis (chronic lymphocytic thyroiditis) Hashimoto’s encephalitis/encephalopathy Horton disease (giant cell arteritis, temporal aerteritis,cranial arteritis) Hypogammaglobulinemia[autoimmunecoach.co.uk] In literature, although the evidence for association between AS and periodontitis as well as AS and HLA-B27 are there but the association of aggressive periodontitis in HLA-B27[ncbi.nlm.nih.gov] ' toe Generalized swelling of fore foot Vasculitis Note: Does not tend to affect foot in sero-negative arthritides Radiographs Bone/periosteal fluffy/'whiskery' proliferation[medical-dictionary.thefreedictionary.com]

  • Spondylo-Ocular Syndrome

    Thyroiditis , Hyperadrenalism , Hyperparathyroidism , Hyperthyroidism , Hypogonadotropic hypogonadism -- Syndactyly , Hypopituitaryism , Multiple endocrine neoplasia type[wikidoc.org] […] may be associated (sausage digits) Involvement of DIP joints of toes think of Reiters or psoriasis Backache and stiffness secondary to sacroiliitis and spondylitis common[flinders.edu.au] A high percentage of people with these diseases share a similar gene called HLA B27.[my.clevelandclinic.org]

  • Spondylitic Aortitis

    .- Subacute Thyroiditis (De Quervain).- Painless Thyroiditis.- Hashimoto's Thyroiditis.- Myxedema.- Polyglandular Failure.- Congenital Adrenal Hyperplasia Due to 11-?[booktopia.com.au] HLA-B27 antigen. Social class.[iritis.org] Localized: T-cells and autoantibodies directed against a single cell type or organ - Hashimoto thyroiditis - Autoimmune atrophic gastritis - Autoimmune hemolytic anemia 2.[flashcardmachine.com]

  • Polyarticular Juvenile Idiopathic Arthritis

    The most frequent autoimmune disorder seen was Hashimoto's thyroiditis.[arthritis-research.biomedcentral.com] There may have been a swollen, ‘sausage’ shaped toe, when your child was younger that got better on its own; this is known as dactylitis [dak-ti-li-tis].[jia.org.uk] B27-positivity in males with onset of arthritis after 6 years of age.[orpha.net]

  • Thumb Deformity - Alopecia - Pigmentation Anomaly Syndrome

    There’s no clear consensus on why autoimmune diseases like Hashimoto’s thyroiditis, lupus, and rheumatoid arthritis occur more frequently in women.[ruthieharper.com] Chronic sarcoid dactylitis typically affects young adults; the fingers and toes become sausage-shaped with spindling.[idoj.in] Chlamydia trachomatis); more common in human leukocyte antigen (HLA) B27 tissue-type males; see keratoderma blenorrhagicum restless-leg syndrome overwhelming need to move[medical-dictionary.thefreedictionary.com]

  • Polyarthritis

    Thyroid ultrasound demonstrated parenchymal changes consistent with Hashimoto’s disease. Ultrasound of the wrist revealed extensive arthritis with tendovaginitis.[thieme-connect.com] Anti-citrullinated protein antibody (ACPA), rheumatoid factor, human leucocyte antigen (HLA) B27 and imaging are routinely employed for the early diagnosis of RA and spondyloarthritis[ncbi.nlm.nih.gov] ) is another classic sign of spondyloarthropathies; this condition, often referred to as “sausage digits,” is caused by a combination of synovitis and enthesitis 22 ( Figure[aafp.org]

  • Arthritis of Ulcerative Colitis

    ’s is an autoimmune attack on the inside of your thyroid gland.[climwatadapt.eu] HLA-B27 related arthritis and bowel inflammation. Part 2. Ileocolonoscopy and bowel histology in patients with HLA-B27 related arthritis. J Rheumatol 1985;12:294-8. 3.[jmedsoc.org] Dactylitis was diagnosed when typical findings of sausage fingers or toes due to inflammation had been present.[academic.oup.com]

  • Deafness-Small Bowel Diverticulosis-Neuropathy Syndrome

    The NINDS, Guillain-Barre Information Sheet H Hanot Syndrome see Primary biliary Cirrhosis Hashimoto’s thyroiditis also called autoimmune thyroiditis and chronic lymphocytic[equilibrium-health.com] Signs: Sausage fingers: Swelling of the tendon sheath of the hands. DIP joints may be inflamed unilaterally.[kumc.edu] B27 associated spondyloarthropathy, iritis, oligoarthritis Approved adalimumab HLA B27 associated spondyloarthropathy, iritis, oligoarthritis Approved renewal adalimumab[pharmac.govt.nz]

  • Transient Sarcoidosis

    Other associations of sarcoid and the thyroid include goitre, sarcoid thyroiditis, Hashimotos thyroiditis, de Quervains thyroiditis, painful thyroid enlargement, Hurthle cell[academic.oup.com] In approximately12%, osseous granulomas are present, most commonly in the phalanges of the fingers and toes.[dermaamin.com] Etiology Speculative Familial cases – positive association with HLA-1, -B8, -B13, -DR3 and –B27.[slideshare.net]

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