Create issue ticket

2 Possible Causes for Hearing Impairment May Improve with Age

  • Pelizaeus-Merzbacher Disease

    Pelizaeus Merzbacher Disease (PMD) is an X-linked developmental defect of myelination that causes childhood chronic spastic encephalopathy. Its genetic etiology can be either a duplication (or other gene dosage alterations) or a punctual mutation at the PLP1 locus. Clinically, it presents with developmental delay,[…][]

  • Cornelia De Lange Syndrome

    Since it is unusual for hearing to improve rather than worsen, it seems correct audiological assessment is difficult.[] […] at age 2 years.[] Many caretakers report that their children were diagnosed as severely hearing impaired at birth, moderately impaired at 12 months, and mildly impaired or without impairment[]

Further symptoms