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14 Possible Causes for Heart Murmur, Impaired Exercise Tolerance, Peripheral T Cells Decreased

  • Patent Ductus Arteriosus

    Symptoms A heart murmur is usually the first sign of PDA newborns. A small PDA may not cause significant problems, so it is usually not treated.[preemies.about.com] Pathogenesis • Escape from regulatory control of Helper T cells directed against these antigens • Defective intraocular T cell regulation of B cellsDecreased helper to[slideshare.net] […] of breath, failure to thrive, tachycardia, heart murmur Complications Heart failure, Eisenmenger's syndrome, pulmonary hypertension Causes Idiopathic Risk factors Preterm[en.wikipedia.org]

  • Graves Disease

    The lungs were clear and the heart rhythm was regular without murmur, click, or gallop.[casesjournal.biomedcentral.com] Notably, HLA-DR14, a known risk factor for GD in Japanese individuals and the decreased regulatory T-cell numbers that were seen in the pediatric case, may affect the early[ncbi.nlm.nih.gov] Central and peripheral tolerance and Th1 cells appeared to be associated with the pathogenesis of GD in 22qDS.[ncbi.nlm.nih.gov]

  • Viral Myocarditis

    Arrhythmias, heart murmurs, third and fourth heart sound as well as mild and filiform pulse may be present and syncopes may be experienced.[symptoma.com] Helper-inducer T cells (Lyt 1 cells) decreased significantly on day 7, but there was no change in cytotoxic-suppressor T cells in the peripheral blood.[jstage.jst.go.jp] In infants, symptoms may also include bluish skin, heart murmurs, and a poor appetite.[healthcentral.com]

  • Peripartum Cardiomyopathy

    murmur Heart murmurs 0030148 Increased serum interferon -gamma level 0030356 Left atrial enlargement 0031295 Mitral regurgitation 0001653 Myocarditis Inflammation of heart[rarediseases.info.nih.gov] […] cytokine profile, decreased levels regulatory T cells and a significant reduction in the plasma levels of progesterone, estradiol and relaxin when compared with other normal[joacc.com] Cardiomyopathy is a disease that attacks the muscles of the heart and may lead to life threatening conditions such as heart failure, blood clots, heart murmurs, cardiac arrest[empowher.com]

  • Peripheral Vascular Disease

    A heart murmur can be heard with a stethoscope when the baby has a PDA.[my.clevelandclinic.org] Pathogenesis • Escape from regulatory control of Helper T cells directed against these antigens • Defective intraocular T cell regulation of B cellsDecreased helper to[slideshare.net] Symptoms in patients with a larger PDA include: Breathing difficulties soon after birth (especially in premature babies) Heart murmur: the heart sounds abnormal when a doctor[chop.edu]

  • Aplastic Anemia

    In addition to low blood cell counts, aplastic anemia is characterized by other physical symptoms of anemia such as pale skin and fingernails, rapid pulse, heart murmur and[ucsfbenioffchildrens.org] MATERIALS AND METHODS: A total of 41 patients with AA and 46 patients with hypo-MDS were collected, and the proportions of peripheral blood T lymphocyte subsets, CD3 - CD16[ncbi.nlm.nih.gov] Symptoms Symptoms and Signs of aplastic anemia include: Pale skin Fatigue Weakness Dizziness Lightheadedness Rapid pulse Heart murmur Bruising and tiny areas of bleeding in[drugs.com]

  • Pulmonary Tuberculosis

    An examination of the cardiovascular system revealed accentuated second heart sound (S2) with early diastolic (grade 1/6) and holosystolic (grade 2/6) murmurs at the pulmonic[ncbi.nlm.nih.gov] […] expression in peripheral blood Vγ2Vδ2 T cells (p   0.043, 0.026).[ncbi.nlm.nih.gov] Heart auscultation revealed regular heart rhythm, clear sounds and diastolic murmur 2/6 on the second right intercostal space.[casesjournal.biomedcentral.com]

  • Severe Aplastic Anemia

    Symptoms of Diamond-Blackfan anemia include: Fast heartbeat (tachycardia) Fatigue Heart murmur Pale skin Short height Weak bones Treatments include everything from steroids[webmd.com] Results showed that the percentage of CD4 effector T cells in peripheral blood and bone marrow lymphocytes was decreased in SAA patients.[ncbi.nlm.nih.gov] Symptoms Symptoms and Signs of aplastic anemia include: Pale skin Fatigue Weakness Dizziness Lightheadedness Rapid pulse Heart murmur Bruising and tiny areas of bleeding in[drugs.com]

  • Loeffler Endocarditis

    Aljaroudi et al. [ 32 ] found that hypertrophic cardiomyopathy patients with worse DD had impaired exercise tolerance, with an odds ratio of 3.0 and suggested that TESE should[kjim.org] There were moderate mitral regurgitation confirmed by TTE (grade 2–3/4) and the typical heart murmur at the apex on admission.[ahajournals.org] Recent studies also identified key Th1 and Th17 cytokines in the liver ( 259 ) and on blood cells ( 260 ) and a decreased T regulatory to Th17 cell balance in peripheral blood[doi.org]

  • Lupus Erythematosus

    exercise tolerance are nonspecific.[journals.lww.com] Endocarditis can damage heart valves, which can result in heart murmurs.[lupusresearch.org] Apoptosis rate increased in parallel to the drop-down of elevated CD5 CD19 cells. Peripheral T-cell subsets remained stable under low-dose MTX.[ncbi.nlm.nih.gov]

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