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17 Possible Causes for Heart Murmur, Small Hand, Wide Space Between the First and Second Toe

  • Down Syndrome

    […] nasal bridge, slightly smaller ears, small mouth, decreased muscle tone, loose ligaments, and small hands and feet.[thearc.org] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] The doctor may hear a heart murmur when listening to the baby's chest with a stethoscope.[nlm.nih.gov]

  • Seckel Syndrome

    […] bones, with considerable similarity of the metacarpophalangeal pattern between the two children; (5) relatively small carpals, which have an angular configuration; and (6[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] murmur Heart murmurs 0030148 High palate Elevated palate Increased palatal height [ more ] 0000218 Hip dislocation Dislocated hips Dislocation of hip [ more ] 0002827 Hyperactivity[rarediseases.info.nih.gov]

  • Kenny-Caffey Syndrome Type 1

    hands and feet, hypocalcaemia, hypoparathyroidism, radiologic evidence of cortical thickening of long bones with medullary stenosis, and absent diploic space in the skull[medical-dictionary.thefreedictionary.com] space between the first and second toes.[medcraveonline.com] hands * Small feet * Hypoparathyroidism Causes - Kenny-Caffey syndrome- Type 1 Not supplied.[checkorphan.org]

  • Seckel Syndrome Type 2

    Cerebellar vermis hypoplasia 0001320 Cleft palate Cleft roof of mouth 0000175 Clitoral hypertrophy Enlarged clitoris 0008665 Cone-shaped epiphyses of the phalanges of the hand[rarediseases.info.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] murmur Heart murmurs 0030148 High palate Elevated palate Increased palatal height [ more ] 0000218 Hip dislocation Dislocated hips Dislocation of hip [ more ] 0002827 Hyperactivity[rarediseases.info.nih.gov]

  • Dubowitz Syndrome

    […] feet [ more ] 0001773 Sloping forehead Inclined forehead Receding forehead [ more ] 0000340 Small hand Disproportionately small hands 0200055 Sparse lateral eyebrow Limited[rarediseases.info.nih.gov] The doctors had identified a heart murmur and they told Imogen and husband Ken to keep a close eye on her.[belfasttelegraph.co.uk] Congenital heart defects have been found in 13 cases [ 5 , 23 ].[ncbi.nlm.nih.gov]

  • Atelosteogenesis Type 2

    Note moderate short stature, flat facial profile (fetal face–like appearance), short forearms, and small hands.[thehealthscience.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] murmur 82.[tawnymullins77.blogspot.com]

  • Cutis Laxa

    […] nails, and large hands and feet with deep creases on the palms and soles (fig 11 ).[jmg.bmj.com] Other reported osteoarticular features are: a wide space between the first and second toes; talipes equinovarus; metatarsus adductus; genu recurvatum or genu valgum; flat[scielo.br] First and 2 nd heart sounds were normal in intensity but here was a pansystolic murmur 2-3/6 heard all over the precardium.[ispub.com]

  • Familial Congenital Nasolacrimal Duct Obstruction

    […] and Puffy Hands and Feet, and Eczema OMIM:601138 Guanylate Cyclase 2e, Pseudogene; GUCY2EP OMIM:139290 Guanylate Kinase 3; GUK3 OMIM:139393 Guillain-Barre Syndrome, Familial[informatics.jax.org] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org] murmurs reflect underlying heart disease.[quizlet.com]

  • Adactyly of Foot

    , Hypoplasia of the corpus callosum, Microcephaly, Strabismus, Impaired use of nonverbal behaviors, Short foot , Profound global developmental delay, Small hand ...see more[ncbi.nlm.nih.gov] Synonyms:Anterior Polydactyly Replaces: Anterior Duplication of the Limb, Tibial Polydactyly Foot, Preaxial Polydactyly of Subjective: A widely spaced gap between the first[quizlet.com] Congenital heart disease is something you are born with, such as a murmur. If her artery is becoming slowly blocked, she does not have congenital disease.[lookfordiagnosis.com]

  • Trisomy 10p

    Some of the characteristics of Edward syndrome may include: defects of the kidneys, ureters, heart, lungs and diaphragm cleft lip or cleft palate small skull (microcephaly[betterhealth.vic.gov.au] spaced, inverted nipples, mild pectus excavatum; and a sandal gap between the first and second toes.[jmg.bmj.com] murmur Renal defect Genital defect Cryptorchidism Limb defects Clinodactyly Syndactyly Club foot Wide sandal gap Nail dysplasia Anemia Extra / single palmar creases Narrow[e-sciencecentral.org]

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