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1,234 Possible Causes for hedgehog, modulator 1,, mouse, repeat containing, tetratricopeptide

Did you mean: hedgehog, modulator 1, morus, repeat containing, tetratricopeptide

  • Osteosarcoma

    BACKGROUND: Some studies have demonstrated that the collagen triple helix repeat containing 1 (CTHRC1) protein is abnormally expressed in multiple human solid tumors.[ncbi.nlm.nih.gov] In this article, we describe the development of a preclinical cancer mouse model that enables specific evaluation of the EV-mediated crosstalk between tumor and mesenchymal[ncbi.nlm.nih.gov] CONCLUSIONS: The present study showed that HIF-1 modulated Cyclin D1 expression might through shaping a positive loop with AKT proteins.[ncbi.nlm.nih.gov] Onzin (Plac8) was identified as one of the genes upregulated in p53R172H/ mouse metastatic osteosarcomas.[ncbi.nlm.nih.gov] GFRA1-induced autophagy promoted tumor growth in mouse xenograft models, suggesting a novel function of GFRA1 in osteosarcoma chemoresistance.[ncbi.nlm.nih.gov]

    Missing: tetratricopeptide
  • Nephronophthisis

    […] domain 21B tetratricopeptide repeat domain-containing protein 21B tetratricopeptide repeat-containing hedgehog modulator 1 TTC21B THM1 612014 25660 transmembrane protein[ukgtn.nhs.uk] The pcy mouse is an orthologous model of human NPHP, with a mutation in the Nphp3 gene.[ncbi.nlm.nih.gov] Mutations in NPHP genes cause defects in signaling mechanisms that involve the noncanonical Wnt signaling pathway and the sonic hedgehog signaling pathway, resulting in defects[ncbi.nlm.nih.gov] In addition, we show that a homozygous missense mutation in Nphp3 is probably responsible for the polycystic kidney disease (pcy) mouse phenotype.[ncbi.nlm.nih.gov] 609799 NPHP9 SDCCAG8 serologically defined colon cancer antigen 8 613524 NPHP10 SLSN7 BBS16 LCA 80% TMEM67 transmembrane protein 67 609884 NPHP11 JBTS6 MKS3 BBS TTC21B * tetratricopeptide[chikd.org]

  • Nephronophthisis 4

    […] domain 21B tetratricopeptide repeat domain-containing protein 21B tetratricopeptide repeat-containing hedgehog modulator 1 TTC21B THM1 612014 25660 transmembrane protein[ukgtn.nhs.uk] "Mouse PubMed Reference:" .[en.wikipedia.org] Wnt and hedgehog (Shh) signaling interfere with planar cell polarity by affecting the orientation of the centrosomes and mitotic spindles.[chikd.org] […] and ES Cells Targeting Detail Product Ordering MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry Nphp4 tm598(L1L2_Bact_P) Vector Gene[mousephenotype.org] His groups ́ research focuses on the cellular and molecular processes regulating development of these progenitor cells in the mouse and their contribution to the developing[books.google.com]

  • Epilepsy

    Leu729ThrfsTer6) in TMTC3, encoding transmembrane and tetratricopeptide repeat containing 3, in four siblings with nocturnal seizures and ID.[ncbi.nlm.nih.gov] A mouse model of lithium‑pilocarpine temporal lobe epilepsy was established and anti‑VGKC treatment was administered for 30 days.[ncbi.nlm.nih.gov] Leu729ThrfsTer6) in TMTC3, encoding transmembrane and tetratricopeptide repeat containing 3, in four siblings with nocturnal seizures and ID.[ncbi.nlm.nih.gov] Memory impairment, anxiety, visual attention, inhibitory control and neuronal loss were measured in the mouse model of lithium‑pilocarpine temporal lobe epilepsy.[ncbi.nlm.nih.gov]

    Missing: hedgehog modulator 1
  • Nephronophthisis

    Annotation score: D6RIE4 D6RIE4_HUMAN WD repeat-containing protein 19 WDR19 78 Annotation score: H0Y8K9 H0Y8K9_HUMAN WD repeat-containing protein 19 WDR19 135 Annotation[uniprot.org] The pcy mouse is an orthologous model of human NPHP, with a mutation in the Nphp3 gene.[ncbi.nlm.nih.gov] […] repeat domain 21B tetratricopeptide repeat domain-containing protein 21B tetratricopeptide repeat-containing hedgehog modulator 1 TTC21B THM1 612014 25660 transmembrane protein[ukgtn.nhs.uk] Mutations in NPHP genes cause defects in signaling mechanisms that involve the noncanonical Wnt signaling pathway and the sonic hedgehog signaling pathway, resulting in defects[ncbi.nlm.nih.gov] Two animal models with mutations in the mouse orthologs of the genes involved in the adolescent and infantile forms also exist.[ncbi.nlm.nih.gov]

  • Metastasis

    Recently, it is reported that leucine‑rich repeatcontaining 8A (LRRC8A) is a main molecular determinant of VRAC current.[ncbi.nlm.nih.gov] […] knockout (KO) mice for BMP9 (constitutive Gdf2-deficient), for BMP10 (inducible Bmp10-deficient) and double KO mice (Gdf2 and Bmp10) in a syngeneic immunocompetent orthotopic mouse[ncbi.nlm.nih.gov] […] the expression of target genes via interacting with the components of the NuRD complex including HDACs. [10] [19] [20] MTA1 suppresses transcription of breast cancer type 1[en.wikipedia.org] Moreover, Ras-related protein (Rab-14) and Hedgehog acyltransferase (Hhat) were identified as direct targets of miR-338-3p.[ncbi.nlm.nih.gov] LYVE-1 proteins and mouse myeloma cells.[ncbi.nlm.nih.gov]

    Missing: tetratricopeptide
  • Nephronophthisis

    […] domain 21B tetratricopeptide repeat domain-containing protein 21B tetratricopeptide repeat-containing hedgehog modulator 1 TTC21B THM1 612014 25660 transmembrane protein[ukgtn.nhs.uk] The jck mouse is another model of recessive cystic kidney disease, and this mouse harbors a missense mutation, G448V, in the highly conserved RCC1 domain of Nek8.[ncbi.nlm.nih.gov] Wnt and hedgehog (Shh) signaling interfere with planar cell polarity by affecting the orientation of the centrosomes and mitotic spindles.[chikd.org] Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney.[ncbi.nlm.nih.gov] Nephrocystin: Gene expression and sequence conservation between human, mouse, and Caenorhabditis elegans. J Am Soc Nephrol 2000; 11: 270-82. 35.[sjkdt.org]

  • Visceral Leishmaniasis

    KEYWORDS: Serological diagnosis; Small glutamine-rich tetratricopeptide repeat-containing protein; Vaccine; Visceral leishmaniasis[ncbi.nlm.nih.gov] We have infected different mouse strains and analyzed the development of the disease, studying the parasite's ability to visceralize and whether this ability is influenced[ncbi.nlm.nih.gov] AGMO modulates PAF production by mouse macrophages, suggesting that it may act through the PAF/PAF receptor pathway previously shown to have anti-Leishmania activity.[ncbi.nlm.nih.gov] […] crimson) virulent strain of L. donovani (Ld1S_luci_E2-crimson), favoring a wide range of both in vivo and in vitro investigations, (ii) the establishment of a non-invasive mouse[ncbi.nlm.nih.gov] KEYWORDS: Serological diagnosis; Small glutamine-rich tetratricopeptide repeat-containing protein; Vaccine; Visceral leishmaniasis[ncbi.nlm.nih.gov]

    Missing: hedgehog modulator 1
  • Intestinal Adenoma

    This “lineage tracing” analysis suggests that tumor cells expressing the intestinal crypt stem cell marker Lgr5 (leucine-rich repeat containing G protein–coupled receptor[science.sciencemag.org] Quite strikingly, we identified a core set of DMRs, which is conserved between mouse adenoma and human colon cancer, thus possibly revealing a global panel of epigenetically[ncbi.nlm.nih.gov] Follow-up of single tubular adenomas less than 1 cm is debated and patient-specific, depending primarily on comorbidities and age.[nulytely.com] Apc(Min) mice were crossed with mice in which sonic hedgehog (SHH) was overexpressed specifically in the intestinal epithelium.[ncbi.nlm.nih.gov] Although the molecular mechanism of tumor initiation is complex, several modifier genes have been identified using mouse models, including the ApcMin mouse.[agris.fao.org]

    Missing: tetratricopeptide
  • Nephronophthisis

    […] domain 21B tetratricopeptide repeat domain-containing protein 21B tetratricopeptide repeat-containing hedgehog modulator 1 TTC21B THM1 612014 25660 transmembrane protein[ukgtn.nhs.uk] Nephrocystin: Gene expression and sequence conservation between human, mouse, and Caenorhabditis elegans. J Am Soc Nephrol 2000; 11: 270-82. 35.[sjkdt.org] Genet. (2000) [ Pubmed ] Nephrocystin: gene expression and sequence conservation between human, mouse, and Caenorhabditis elegans.[wikigenes.org] Wnt and hedgehog (Shh) signaling interfere with planar cell polarity by affecting the orientation of the centrosomes and mitotic spindles.[chikd.org] Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney.[ncbi.nlm.nih.gov]