HELLP Syndrome: Causes & Reasons

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Possible Causes for HELLP Syndrome

HELLP Syndrome

HELLP syndrome. [ncbi.nlm.nih.gov]

Management of HELLP Syndrome* FIGURE 1. Suggested approach to the management of patients with HELLP syndrome. [aafp.org]

How is HELLP syndrome diagnosed?There is no specific diagnostic testing for HELLP syndrome. [symptoma.com]

Disseminated Intravascular Coagulation

[…] of the HELLP syndrome is rare. [ncbi.nlm.nih.gov]

KEYWORDS: Acute fatty liver of pregnancy; Endothelial dysfunction; HELLP syndrome; Hemorrhage; Score; Trophoblast [ncbi.nlm.nih.gov]

HELLP syndrome: HELLP syndrome: Hemolysis, Elevated Liver enzymes, Low platelet count Syndrome. [journals.plos.org]

Long Chain Hydroxyacyl-CoA Dehydrogenase Deficiency

syndrome). [emilytam.com]

HELLP syndrome. J Perinat Med 28 : 249–260. Ribes A, Riudor E, Navarro C, Boronat M, Marti M, and Hale DE (1992). [nature.com]

syndrome. [genecards.org]

Hemolytic Uremic Syndrome

A pregnancy complicated by typical hemolytic uremic syndrome (HUS) and hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome is reported. [ncbi.nlm.nih.gov]

[…] represent a treatment for severe HELLP syndrome. [doi.org]

HELLP Syndrome. Lab Med 1997; 28:500-502. Kwaan HC, Ganguly P. Introduction: Thrombotic thrombocytopenic purpura and the hemolytic uremic syndrome. Sem. [path.upmc.edu]

Thrombocytopenia

Shiga toxin-producing Escherichia coli is the most common causative organism in hemolytic uremic syndrome. 26 PREECLAMPSIA AND HELLP SYNDROME Pregnant patients beyond 20 weeks [aafp.org]

HELLP syndrome accounts for 21% of maternal thrombocytopenia in pregnancy. HELLP syndrome is a variant of severe preeclampsia, first described by Dr. [emedicine.medscape.com]

During pregnancy, preeclampsia and the HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome are associated with thrombocytopenia. [aafp.org]

Preeclampsia

Severe preeclampsia with hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome is a leading cause of maternal and neonatal morbidity and mortality worldwide [ncbi.nlm.nih.gov]

What are the symptoms of HELLP syndrome? HELLP syndrome tends to come on quickly but there may be no symptoms. [patient.info]

Successful use of Eculizumab in this case suggests that complement inhibition may be an effective treatment strategy for severe preeclampsia/HELLP syndrome. [ncbi.nlm.nih.gov]

Pregnancy-Induced Hypertension

Pregnancies complicated by HELLP syndrome are associated with poor maternal and fetal outcome. [ncbi.nlm.nih.gov]

The etiology and clinical manifestations of HELLP syndrome are discussed through a review of research findings and a case study. [ncbi.nlm.nih.gov]

In addition, 58% of PIH cases resulting in stroke were complicated by hemolysis, elevated liver enzymes and low platelet count (HELLP) syndrome. [ncbi.nlm.nih.gov]

Acute Fatty Liver of Pregnancy

Published works dealing with liver dysfunction in pregnancy, HELLP syndrome and AFLP were reviewed. [ncbi.nlm.nih.gov]

To our knowledge, this represents the first report of pancreatic panniculitis in association with HELLP syndrome and acute fatty liver of pregnancy. [ncbi.nlm.nih.gov]

How is AFLP different from HELLP syndrome? AFLP is distinguished from HELLP syndrome and other forms of preeclampsia by differences in how the two diseases develop. [preeclampsia.org]

Subcapsular Liver Hematoma

HELLP syndrome (hemolysis, elevation of liver enzymes, and low platelet count) occurs during pregnancy. [ncbi.nlm.nih.gov]

Five patients with subcapsular liver hematoma in HELLP syndrome could be identified. [ncbi.nlm.nih.gov]

Keywords : HELLP Syndrome, Hematoma, Ligation, Liver Diseases, Pre-Eclampsia. [casereports.in]

Liver Hematoma

[…] with preeclampsia and the HELLP syndrome. [ncbi.nlm.nih.gov]

Keywords : HELLP Syndrome, Hematoma, Ligation, Liver Diseases, Pre-Eclampsia. [casereports.in]

Sibai BM, HELLP syndrome; available at https://www.uptodate.com/contents/hellp-syndrome? [scielo.mec.pt]

Massive Hepatic Necrosis

We present a patient with toxemia of pregnancy and the HELLP syndrome [hemolysis (H), elevated liver enzymes (EL), and a low platelet count (LP)] resulting in massive hepatic [ncbi.nlm.nih.gov]

CLINICAL FEATURES About 2–12% of severe eclampsia cases complicated by HELLP syndrome. Both HELLP syndrome and acute fatty liver of pregnancy occur in the 3rd trimester. [demosmedical.com]

HIV-Associated Thrombocytopenia

Shiga toxin-producing Escherichia coli is the most common causative organism in hemolytic uremic syndrome. 26 PREECLAMPSIA AND HELLP SYNDROME Pregnant patients beyond 20 weeks [aafp.org]

Increased destruction: a) Microangiopathic Hemolytic Anemias (MAHA): DIC, TTP/HUS, HELLP syndrome - see Ellen Eaton's recent MR summary for more b) Immune-mediated: ITP, Heparin-induced [errolozdalga.com]

Hemol ysis (Elevated Liver Enzymes and Low Platelets (HELLP) Syndrome): HELLP is exclusive to pregnancy, and is an extreme form of pre-eclampsia. [antimicrobe.org]

Postpartum Hemorrhage of the Uterus

syndrome, sepsis or infection which should be detected immediately to avoid oxygen deprivation and organ damage in the mother. [defranciscolaw.com]

Successful use of recombinant factor VIIa for massive bleeding after caesarean section due to HELLP Syndrome. [jpmiss2.free.fr]

This be an inherited condition or one that develops during pregnancy from complications such as severe preeclampsia, or HELLP syndrome or a placental abruption. [babycenter.com]

Purtscher's Retinopathy

View Article PubMed Google Scholar Stewart MW, Brazis PW, Guier CP, Thota SH, Wilson SD: Purtscher-like retinopathy in a patient with HELLP syndrome. [jmedicalcasereports.biomedcentral.com]

Purtscher-like retinopathy in a patient with HELLP syndrome. Am J Ophthalmol 2007;143:886-7. 5. Agrawal A, McKibbin MA. [meajo.org]

Purtscher-like retinopathy in a patient with HELLP syndrome. Am J Ophthalmol. 2007 May. 143(5):886-7. [Medline]. Holak HM, Holak S. [emedicine.medscape.com]

Hepatic Rupture

The causes of hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome or hepatic hemorrhage as a serious complication of HELLP are not known. [ncbi.nlm.nih.gov]

This report describes 3 cases of extensive spontaneous hepatic rupture in pregnant women with HELLP syndrome. [ncbi.nlm.nih.gov]

This patient's findings suggested HELLP syndrome, which was subsequently diagnosed. [ncbi.nlm.nih.gov]

Thrombocytopenia Due to Sequestration

Shiga toxin-producing Escherichia coli is the most common causative organism in hemolytic uremic syndrome. 26 PREECLAMPSIA AND HELLP SYNDROME Pregnant patients beyond 20 weeks [aafp.org]

HELLP syndrome accounts for 21% of maternal thrombocytopenia in pregnancy. HELLP syndrome is a variant of severe preeclampsia, first described by Dr. [emedicine.medscape.com]

Hemol ysis (Elevated Liver Enzymes and Low Platelets (HELLP) Syndrome): HELLP is exclusive to pregnancy, and is an extreme form of pre-eclampsia. [antimicrobe.org]

Cholestasis of Pregnancy

PREECLAMPSIA/ECLAMPSIA AND HELLP SYNDROME Preeclampsia is a syndrome that is unique to pregnancy. [wjgnet.com]

“HELLP” SYNDROME • Hemolysis, Elevated Liver enzymes,and Low Platelet count (HELLP) syndrome. • Multi-system disease variant of severe preeclampsia that is characterized by [slideshare.net]

syndrome. 26, 27 Notable hepatic abnormalities in the HELLP syndrome include hemolysis (with elevated bilirubin levels and lactate dehydrogenase levels greater than 600 IU [aafp.org]

Eclampsia

syndrome. [ncbi.nlm.nih.gov]

Three patients had evidence of worsening severity of disease characterized by acute renal failure with oliguria, HELLP Syndrome, Intrauterine Growth Restriction and adverse [ncbi.nlm.nih.gov]

Severe hypertension (SBP ≥ 160 mm Hg and/or DBP ≥ 110 mmHg), thrombocytopenia < 100.000/μL, liver transaminases above twice the normal values, HELLP syndrome, renal failure [ncbi.nlm.nih.gov]

Mitochondrial Trifunctional Protein Deficiency

Maternal HELLP syndrome occurred in two mothers independently of the fetal phenotype. [ncbi.nlm.nih.gov]

syndrome. [ghr.nlm.nih.gov]

Pre-eclampsia, eclampsia and HELLP syndrome accounted for 5 (11.6%). [science.gov]

Acquired Hemolytic Anemia

LEVEL MOST SENSITIVE 64 HELLP SYNDROME - TX PROMPT DELIVERY OF INFANT SUPPORTIVE CARE FOR SEIZURES AND HTN CRISIS STEROIDS MAY HELP FETAL LUNGS, BUT NO BENEFIT TO HELLP SYNDROME [slideplayer.com]

syndrome) Infections (Note: Direct Coombs test is sometimes positive in hemolytic anemia due to infection) Malaria Babesiosis Sepsis Membrane disorders Paroxysmal nocturnal [en.wikipedia.org]

syndrome) Infections (Note: Direct Coombs test is sometimes positive in hemolytic anemia due to infection) Malaria Babesiosis Septicemia Membrane disorders Paroxysmal nocturnal [ipfs.io]

Microangiopathic Hemolytic Anemia

The syndrome of hemolytic anemia, elevated liver enzymes and low platelets (HELLP) can accompany preeclampsia and eclampsia. [ncbi.nlm.nih.gov]

[…] malignant hypertension -thrombotic thrombocytopenic purpura-hemolytic uremic syndrome -Hemolytic uremic syndrome (HUS) -Disseminated intravascular coagulation (DIC) -HELLP [quizlet.com]

Disseminated intravascular coagulation HELLP syndrome Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome Cancer Malignant hypertension Scleroderma renal crisis [en.wikipedia.org]

Short Chain Acyl CoA Dehydrogenase Deficiency

SCAD deficiency may be associated with maternal HELLP syndrome. [ncbi.nlm.nih.gov]

His mother developed a hemolysis-elevated liver enzymes-low platelets (HELLP) syndrome while pregnant with the index patient. Results. [pediatrics.aappublications.org]

Mothers with an LCHADD fetus often have HELLP syndrome (hemolysis, elevated liver function tests, and low platelet count) during pregnancy. [merckmanuals.com]

Disorder of Lipid Metabolism

This article is available to subscribers. Subscribe now. Already have an account? Sign in Original Article Free Preview Archive William J. Bank, M.D., Salvatore DiMauro, M.D., Eduardo Bonilla, M.D., David M. Capuzzi, M.D., and Lewis P. Rowland, M.D. Abstract Two brothers, 29 and 33 years of age, had recurrent myoglobinuria,[…] [nejm.org]

Toxic Shock Syndrome

Toxic shock syndrome (TSS) is a condition caused by bacterial toxins. Symptoms may include fever, rash, skin peeling, and low blood pressure. There may also be symptoms related to the specific underlying infection such as mastitis, osteomyelitis, necrotising fasciitis, or pneumonia.TSS is caused by bacteria of either[…] [en.wikipedia.org]

Hepatic Infarction

HELLP syndrome is a rare disease in China, and 20% of patients with severe preeclampsia have been accompanied with HELLP syndrome, which is characterized by the presence of [ncbi.nlm.nih.gov]

We recommend that severely ill patients with HELLP syndrome having epigastric pain should undergo CT imaging of the liver. [ncbi.nlm.nih.gov]

The management of fulminant liver failure complicated with HELLP syndrome should be multidisciplinary. [ncbi.nlm.nih.gov]

Placental Insufficiency

syndrome. [ncbi.nlm.nih.gov]

syndrome, delivery RESULTS: Adverse perinatal outcomes occurred in 14 (23%) women; 3 (4.9%) losses 20 weeks, 4 (6.6%) IUGR, 7 (11.5%) severe pre-eclampsia/HELLP syndrome, [ncbi.nlm.nih.gov]

The results suggest that the vitamin B6-dependent trans-sulfuration pathway is activated in pre-eclampsia and HELLP syndrome, probably by oxidative stress. [ncbi.nlm.nih.gov]

Traumatic Hemolytic Anemia

[…] or related disorders such as the HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet count), and systemic sclerosis renal crisis Rare cases of significant [merckmanuals.com]

HELLP syndrome CT of liver to evaluate for acute fatty liver of pregnancy or hepatic rupture. [oncologynurseadvisor.com]

The HELLP syndrome can occur with minimal signs or symptoms of preeclampsia. [emjournal.net]

Subcapsular Kidney Rupture

Keywords : HELLP Syndrome, Hematoma, Ligation, Liver Diseases, Pre-Eclampsia. [casereports.in]

Ruptured subcapsular hepatic haematoma secondary to “HELLP syndrome.” Acta Chirurgica Belgica 1995; 95: 251. 3. Cozzi PJ, and Morris DL. [journals.lww.com]

SLH, a rare complication of preeclampsia and HELLP, occurs in about 1-2% of all preeclampsia cases and HELLP syndrome [ 1, 2 ]. [casereports.in]

Atypical Hemolytic Uremic Syndrome

We found that HELLP syndrome is associated with increased complement activation as assessed with the modified Ham test. [ncbi.nlm.nih.gov]

elevated liver enzymes, and low platelet count (HELLP) syndrome followed by thrombotic thrombocytopenic purpura and hemolytic uremic syndrome during her second pregnancy [ncbi.nlm.nih.gov]

In addition, three women (C.3, C.4, and C.5) were considered to have preeclampsia or HELLP syndrome before the definitive diagnosis of p-aHUS was made. [jasn.asnjournals.org]

Waters-West Syndrome

[…] use of steroids as a therapeutic maneuver in HELLP syndrome.) [clinicaladvisor.com]

245010 ALDH2 Hangover, susceptibility to, 610251 CPOX Harderoporphyria, 121300 PANK2 HARP syndrome, 607236 HPD Hawkinsinuria, 140350 HADHA HELLP syndrome, maternal, of pregnancy [gsdseq.ir]

H A D H 4q25 3-hydroxyacyl-CoA dehydrogenase deficiency 231530 Hyperinsulinemic hypoglycemia, familial, 4 609975 H A D H A 2p23.3 Fatty liver, acute, of pregnancy 609016 HELLP [institutobernabeu.com]