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3,982 Possible Causes for Hematemesis, Hepatomegaly, Onset of Disease between 25 and 40 Years of Age

  • Wilson Disease

    CONCLUSIONS: Wilson disease can present with only significantly increased transaminases activity and hepatomegaly or liver failure, but neurological symptoms are very rare[ncbi.nlm.nih.gov] Onset is slow and begins between 11 and 25 years of age. Signs and Symptoms In about 40 to 50% of patients, the disease first affects the central nervous system (CNS).[diagnose-me.com] […] develop and can result in signs of fulminant hepatic failure, including the following: Ascites and prominent abdominal veins Spider nevi Palmar erythema Digital clubbing Hematemesis[emedicine.medscape.com]

  • Liver Cirrhosis

    Cardinal symptoms include fasting hypoglycemia, lactic acidosis and hepatomegaly as well as neutropenia.[ncbi.nlm.nih.gov] The child presented with complaints of malena, hematemesis and variceal bleed.[ncbi.nlm.nih.gov] […] aminotransferase, and prothrombin international normalized ratio; LR, 0.09; 95% CI, 0.03-0.31); a platelet count 160 x 10(3)/μL (LR, 0.29; 95% CI, 0.20-0.39); or the absence of hepatomegaly[ncbi.nlm.nih.gov]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Malignant Gastric Neoplasm

    Signs may include a palpable enlarged stomach with succussion splash; hepatomegaly; periumbilical metastasis (Sister Mary Joseph nodule); and enlarged lymph nodes such as[emedicine.medscape.com] Case 1 in an 11-year-old girl presented with hematemesis. A gastroscopic examination was performed, and a pathological diagnosis of signet ring cell carcinoma was made.[ci.nii.ac.jp] […] of difficult or painful swallowing (i.e. dysphagia, odynophagia) Heartburn Retrosternal discomfort or pain Nausea, vomiting Fever, sepsis Abdominal pain Epigastric pain Hematemesis[physio-pedia.com]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Progressive Familial Intrahepatic Cholestasis

    RESULTS: All four patients were presented with jaundice, pruritus, hepatomegaly, sleep disturbance. They fulfilled the criteria for PFIC. The surgery was uneventful.[ncbi.nlm.nih.gov] He underwent a biliary diversion at 3½ years of age but subsequently died secondary to massive hematemesis.[thieme-connect.com] Clinical signs of cholestasis (discolored stools, dark urine) usually appear in the first months of life with recurrent or permanent jaundice associated with hepatomegaly[orpha.net]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Portal Hypertension

    In POEMS syndrome, a rare multi-systemic disease, the most frequent liver manifestation is hepatomegaly(1).[ncbi.nlm.nih.gov] A 62-year-old Brazilian man who lived in endemic areas of tropical diseases had an episode of hematemesis associated with portal hypertension.[ncbi.nlm.nih.gov] Subsequent Problems That Can Develop Due to Portal Hypertension: Hepatomegaly (enlarged liver), splenomegaly (enlarged spleen due to increased pressure in the liver), esophageal[arpkdchf.org]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Budd-Chiari Syndrome

    A 10-month-old boy presented with ascites, right pleural effusion, and hepatomegaly after consumption of herbal drinks for 3 months.[ncbi.nlm.nih.gov] A 33-year-old man who presented with abdominal distension, hematemesis, shortness of breath was found to have liver cirrhosis, portal hypertension and Budd-Chiari Syndrome[ncbi.nlm.nih.gov] Classic triad includes abdominal pain, ascites, and hepatomegaly. Most patients present with RUQ abd...[5minuteconsult.com]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Congenital Hepatic Fibrosis

    Hepatomegaly was present in all patients and splenomegaly in all but one.[ncbi.nlm.nih.gov] The patient was discharged in improved condition and has no recurrent hematemesis.[jpatholtm.org] The age at presentation ranged from 1.8-14 years (mean: 7.5 years); clinical manifestations at diagnosis were splenomegaly (12), hepatomegaly (11), failure to thrive (10),[ncbi.nlm.nih.gov]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Schistosomiasis

    Physical examination is notable for hepatomegaly, most prominent in the left hepatic lobe. She also has an urticarial rash in her left foot.[medbullets.com] Particularly, we asked about death in the family if any, history of schistosomiasis, abdominal swelling, and hematemesis.[ncbi.nlm.nih.gov] Pediátrica, Hospital Universitario Vall d’Hebron, Barcelona, Spain Article An 11-year-old black girl from Equatorial Guinea was admitted to our hospital to investigate fatigue, hepatomegaly[revespcardiol.org]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Malaria

    Patients with heavy hepatocyte load may present with hepatomegaly.[symptoma.com] Enlargement of the liver (hepatomegaly) and spleen (splenomegaly) may be found during a physical examination.[betterhealth.vic.gov.au] Symptoms Fever, often recurring Chills Rigors Headache Cough Myalgia Gastrointestinal upset Signs Fever Splenomegaly Hepatomegaly Jaundice /- abdominal tenderness Signs of[patient.info]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Hepatitis C

    Additional symptoms are non-specific and may comprise hepatomegaly, upper abdominal pain, nausea, vomiting and loss of appetite.[symptoma.com] The majority of infected children have intermittent or chronically elevated aminotransferase levels [14], [20], [21], with hepatomegaly being the only common physical finding[doi.org]

    Missing: Onset of Disease between 25 and 40 Years of Age

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