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197 Possible Causes for Hematochezia, Pallor, Splenomegaly

  • Gastrointestinal Hemorrhage

    This is often due to pre-existing liver disease and splenomegaly.[geekymedics.com] Seek immediate medical care (call 911) for serious symptoms, pale skin or pallor and difficulty breathing, severe abdominal pain , vomiting blood or black material, or change[healthgrades.com] The most common symptom is abdominal pain, while the incidence of hematochezia is relatively low.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[ncbi.nlm.nih.gov] Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy[orpha.net] Gastrointestinal hemorrhages, hematochezia and melena, are commonly reported. Hepatosplenomegaly may cause upper abdominal pain, portal hypertension and ascites.[symptoma.com]

  • Acute Myelocytic Leukemia

    Typical symptoms are spongy and bleeding gums, anemia, fatigue, fever, dyspnea, moderate splenomegaly, joint and bone pain, and repeated infections.[medical-dictionary.thefreedictionary.com] The main clinical picture consists of a short time period with pallor, fatigue, fever, infections and hemorrhages. Presence of all these features is not compulsory.[orpha.net] Patients may claim a propensity for epistaxis, bleeding gums, melena and hematochezia, and hematuria.[symptoma.com]

  • Myeloproliferative Disease

    CML: demonstrates increased production of neutrophils and marked splenomegaly.[ncbi.nlm.nih.gov] […] stupor from leukostasis Left upper quadrant and left shoulder pain as a consequence of splenic infarction and perisplenitis Clinical symptoms can include the following: Pallor[emedicine.com] The unusual case of myeloproliferative disease described here is characterized by the following features: (1) a clinically completely silent course for 11 years without splenomegaly[ncbi.nlm.nih.gov]

  • Myelodysplasia

    Therapy with granulocyte-colony stimulating factor (G-CSF) and granulocyte-monocyte-colony stimulating factor (GM-CSF) caused splenomegaly and severe thrombocytopenia, which[ncbi.nlm.nih.gov] Symptoms are referable to the specific cell line most affected and may include fatigue, weakness, pallor (secondary to anemia), increased infections and fever (secondary to[msdmanuals.com] We present a 2-year-old boy with splenomegaly, leukocytosis, thrombocytopenia, anemia, and excess myeloblasts with easily seen Auer rods, and marked dysgranulopoiesis and[ncbi.nlm.nih.gov]

  • Familial Myelofibrosis

    Treatment Splenomegaly and extramedullary haemopoiesis Medical treatment remains the treatment of choice for most patients with symptomatic splenomegaly.[onlinelibrary.wiley.com] The illness presented with pallor, haemorrhagic symptoms, and hepatosplenomegaly, and the blood picture was that of pancytopenia and leucoerythroblastosis.[ncbi.nlm.nih.gov] Anemia is one of the hallmarks of pancytopenia and is associated with fatigue, pallor, and cyanosis. Children may also be tachypneic due to hypoxia.[symptoma.com]

  • Acute Myeloid Leukemia with Myelodysplasia-related Changes

    On the one hand, anemia accounts for pallor, fatigue, and limited resistance to exercise.[symptoma.com] These conditions manifest in: Pallor, fatigue, reduced resistance to exercise, and dyspnea as symptoms of anemia Increased susceptibility to infections as a sign of leukopenia[symptoma.com]

  • Sickle Cell Disease

    In two mouse SCD models, Berkeley and SAD, inhibition of red blood cell dehydration and sickling was achieved with correction of hematological parameters, splenomegaly, and[ncbi.nlm.nih.gov] ASS: Inquire about noticeable increase in weakness or pallor, syncope, and sudden abdominal distention.[web.archive.org] A quick rectal exam reveals normal stool with no melena or hematochezia.[emergencymedicinecases.com]

  • Adenocarcinoma of the Rectum

    Therefore, a longer duration of oxaliplatin therapy can give rise to portal hypertension, often noted on the preoperative CT scan as splenomegaly and ascites. 34 In addition[ascopubs.org] We describe a 13-year-old girl with short stature and delayed puberty who presented with hematochezia and recurrent abdominal pain for 1 year, and progressive weight loss[ncbi.nlm.nih.gov] Signs Pallor Abdominal mass PR mass Jaundice Nodular liver Ascites Rectal metastasis travel along portal drainage to liver via superior rectal vein as well as systemic drainage[de.slideshare.net]

  • Cecal Adenocarcinoma

    […] cell carcinoma印環細胞癌 sinusoid類洞 small intestine小腸 spasm of the esophagus食道痙攣 sphincter of Oddi (SO)オッジ括約筋(オッジ筋) splanchnic nerve内臓神経 splanchnic plexus内臓神経叢 splenectomy脾摘術 splenomegaly[tokyo-med.ac.jp] Case report: An 18-year-old female Egyptian patient was admitted with hematochezia and remarkable anemia.[dovepress.com] Anemia can lead to fatigue, weakness and pallor. The cecum, a pouchlike structure, lies very close to the appendix.[livestrong.com]

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