Hematocrit Decreased: Causes & Reasons

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Possible Causes for Hematocrit Decreased

Congenital Hemolytic Anemia

After partial splenectomy, children overall had decreased transfusion requirements, increased hematocrits, decreased bilirubin levels, decreased reticulocyte counts, and elimination [ncbi.nlm.nih.gov]

Outcome variables included perioperative complications, transfusion requirements, hematocrits, reticulocyte counts, bilirubin levels, splenic sequestration, and splenic regrowth [ncbi.nlm.nih.gov]

Anemia

Your healthcare provider will be looking for a decrease in hematocrit or hemoglobin. [verywellhealth.com]

Throughout fetal life, erythrocytes decrease in size and increase in number: hematocrit increases from 30% to 40% during the second trimester to 50% to 63% at term. [pedsinreview.aappublications.org]

An interesting question is the fact that the decrease in hematocrit could be a marker for other factors that increase the mortality in patients with severe HF, for example [revespcardiol.org]

Plummer-Vinson Syndrome

Lab test normally expose “iron-deficiency” anemia with values of hemoglobin, hematocrit, serum iron and ferritin decreased and increased total of iron binding capacity. [syndrome.org]

Investigations Complete blood cell (CBC) counts: decreased values of hemoglobin, hematocrit, mean corpuscular volume Peripheral blood smears: hypochromic microcytic anemia [slideshare.net]

Iron studies: decreased values of serum iron and ferritin, and increased total iron binding capacity 16. [slideshare.net]

Iron Deficiency Anemia

normal unless infection is present Cells are iron deficient; as hematocrit falls below 30%, hypochromic microcytic cells appear, followed by a decrease in MCV White blood [medical-dictionary.thefreedictionary.com]

Anemia characterized by decreased or absent iron stores, low serum iron concentration, low transferrin saturation, and low hemoglobin concentration or hematocrit value. [icd9data.com]

[…] saturation, and low hemoglobin concentration or hematocrit value. [icd10data.com]

HELLP Syndrome

The laboratory investigations before death revealed evidence of hemolysis, which is decreased hematocrit, elevated lactate dehydrogenase (865 U/L), and low platelet count [ncbi.nlm.nih.gov]

[…] normal: decreased serum haptoglobin levels may be present indicating HELLP) [2] Liver Enzymes: As high as 4,000 U per L [2] Platelets: As low as 6,000 per mm 3 ( anything [physio-pedia.com]

Evidence of hemolysis is also reflected by a declining hematocrit or hemoglobin and decreased haptoglobin. [clinicaladvisor.com]

Primary Male Hypogonadism

Check hematocrit; if it increases to >54%, stop therapy until hematocrit decreases into the normal range. [clinicaladvisor.com]

Risks of Testosterone/Androgen Therapy Fluid retention GynecomastiaAcne/oily skin Increases hematocrit Decreases HDL cholesterol (cardiovascular risk?) [enotes.tripod.com]

If hematocrit is greater than 52%, stop therapy until it decreases to a safe level and re-evaluate the patient for hypoxia and sleep apnea. [bcmj.org]

Splenic Rupture

Laboratory studies include a basic biochemical panel and a complete blood count (CBC), which will often show a decreased hematocrit. [symptoma.com]

The laboratory analysis revealed a decrease in her hemoglobin from 13.8 g/dl to 9 g/dl and a significant drop in her hematocrit. [wjes.biomedcentral.com]

A complete blood count revealing a decreased hematocrit and imaging studies, mainly ultrasonography and computed tomography, are used for confirmation, whereas history taking [symptoma.com]

Toxoplasmosis

HIV infected patients required to be evaluated for neutrophil counts two times/week and platelets and hematocrit once/month ( 127 ). [antimicrobe.org]

Neutrophil count below 1000/µl or platelets 90,000/µl necessitate to escalate folinic acid dosage or withdraw when neutrophils decrease 500/µl to reverse cytopenia. [antimicrobe.org]

Chronic Kidney Insufficiency

In most patients, the hematocrit reaches about 20 to 25% by the time that ESRD develops. [meddean.luc.edu]

Progressively more severe normochromic, normocytic anemia develops as the GFR and renal erythropoietin secretion decrease. [meddean.luc.edu]

Polymyalgia Rheumatica

For the patients receiving ruxolitinib, the mean hematocrit level decreased from 45.9+/–5.6% to 41.0+/–5.0% after 6 months of treatment. [ajmc.com]

[…] in hematocrit from baseline. [clinicaltrials.gov]

The World Health Organization has diagnostic guidelines based on hemoglobin and hematocrit levels and red cell mass determination. [merckmanuals.com]

Gastrointestinal Hemorrhage

On day three, his hemoglobin and hematocrit were stable at 10 g/dL and 30%, INR 1.6, he was extubated and off vasoactive medications. [ncbi.nlm.nih.gov]

Massive LGIB is defined as follows: Note the following: Passage of a large volume of red or maroon blood through the rectum Hemodynamic instability and shock Initial decrease [emedicine.medscape.com]

Day six of hospitalization, he began having maroon stools, his hemoglobin decreased to 8.1 g/dL and his platelets to 81 × 1000/mcL. [ncbi.nlm.nih.gov]

Therapeutic Phlebotomy

Defy Medical patients who receive therapeutic phlebotomy for the treatment of high hematocrit and high blood pressure have been observed to have an immediate decrease of blood [defymedical.com]

[…] to decrease the risk of complications. [emedicine.medscape.com]

Patients can be phlebotomized once or twice a week to reduce the hematocrit to less than 45%. [emedicine.medscape.com]

Cold Agglutinin Disease

The MCHC and MCH values will be increased due to decreased hematocrit and RBC count. Other causes of invalid red cell indices have to be ruled out. [keralamedicaljournal.com]

Complete blood count (CBC) showed falsely decreased RBC count and hematocrit and falsely elevated MCV and MCHC. [jbclinpharm.org]

The RBC count will be decreased due to doublet erythrocytes being counted as a single cell, thus resulting in a falsely high MCV. Hematocrit will also be lowered. [keralamedicaljournal.com]

Thalassemia Minor

Abstract Patients with heterozygous beta-thalassemia minor have a decreased hematocrit (HCT). [ncbi.nlm.nih.gov]

[…] amount of Hb A and Hb A 2 Increased amount of Hb F (15 - 20%) If red blood cells are normochromic and normocytic, the RBC, Hb, and Hematocrit (HCT) test values follow in [labce.com]

Decreased amount of Hb A Variable amount of Hb A 2 Hb F is usually increased Severly decreased amount of Hb A Variable amount of Hb A 2 Usually an increased amount of Hb F Decreased [labce.com]

Hereditary Elliptocytosis

Post-splenectomy, patients with HE or HPP exhibit increased hematocrit, decreased reticulocyte counts, and improved clinical symptoms. [cancertherapyadvisor.com]

Complete blood count (CBC): may show following findings Decreased hemoglobin (Hb) Decreased hematocrit (Hct) Normal mean corpuscular volume (MCV) Increased mean corpuscular [stepwards.com]

Congenital Dyserythropoietic Anemia

Following delivery the infant had serial blood counts performed over a 6-week period, which noted a steady decrease in her hematocrit to 16%. [bloodjournal.org]

Hereditary Spherocytosis

A complete blood count (CBC) may show increased reticulocytes, a sign of increased red blood cell production, and decreased hemoglobin and hematocrit. [en.wikipedia.org]

Reticulocytes decreased to 0%. Spherocytosis was present on the peripheral blood smear. [bmcresnotes.biomedcentral.com]

/l (granulocytes, 35%; lymphocytes, 44%; atypical lymphocytes, 9%; and monocytes, 12%), red blood cell count was 1.68 × 10 12 /l; hemoglobin concentration was 5.4 g/dl; hematocrit [bmcresnotes.biomedcentral.com]

Waldenstrom Macroglobulinemia

Acute decreases in hematocrit were observed during first 2 weeks of lenalidomide therapy in 13/16 (81%) patients with a median hematocrit decrease of 4.4% (1.7-7.2%). [clinicaltrials.gov]

Median serum IgM decreased from 3670 to 1590 mg/dL (P < .001), whereas median hematocrit rose from 33.0% to 37.6% (P = .004) at best response. [ncbi.nlm.nih.gov]

Median serum IgM decreased from 3670 to 1590 mg/dL ( P < .001), whereas median hematocrit rose from 33.0% to 37.6% ( P = .004) at best response. [doi.org]

Pernicious Anemia

The CBC should demonstrate anemia, as shown by a decrease in hemoglobin and hematocrit (hemoglobin concentration less than 13 g/dL for men and less than 12 g/dL for women) [statpearls.com]

[…] in serum vitamin B 12 and the decline in hematocrit. [aafp.org]

Steroids were then decreased to prednisone 40 mg and patient was discharged home. [hindawi.com]

Nephroblastoma

41.7 %) and hematocrit (13.9 %). [ncbi.nlm.nih.gov]

The most frequently decreased lymphocyte subpopulation was CD8 (15.5%). [ncbi.nlm.nih.gov]

The most frequent abnormal findings were increased proportion of NK cells (38.5 %), B lymphocytes (38,52 %), decreased number of erythrocytes (25.2 %), hemoglobin levels [ncbi.nlm.nih.gov]

Hepatocellular Carcinoma

Initial laboratory results showed elevated liver enzymes and a slight decrease in the hematocrit and hemoglobin count. [scielo.br]

Inflammatory Bowel Disease Type 1

Surgical Management of Cor Pulmonale Phlebotomy is indicated in patients with chronic cor pulmonale and chronic hypoxia causing severe polycythemia, defined as hematocrit [emedicine.medscape.com]

Phlebotomy results in a decrease in mean pulmonary artery pressure, a decrease in mean pulmonary vascular resistance, [44] and an improvement in exercise performance in such [emedicine.medscape.com]

Aplastic Anemia

The differential white blood count shows a decrease in most types of cells but not lymphocytes. [labtestsonline.org]

Hemoglobin and/or hematocrit may be low. RBC and WBC counts are low. Platelet count is low. Red blood cell indices are usually normal. [labtestsonline.org]

Porphyria

Laboratory tests revealed hypokalemia, hyponatremia, low RBC count (3.35 T/L), macrocytic anemia (Hb: 10,7 g/dL; MCV: 104 fL), decreased hematocrit (31.0 %), hypoalbuminemia [journals.viamedica.pl]

(33.4 g/L), decreased APTT, increased fibrinogen, leukocytosis (13.66 G/L) and a slight rise in C Reactive Protein (CRP levels 26.6 mg/dL). [journals.viamedica.pl]

Pulmonary Tuberculosis

Laboratory Tests Hematological investigation typically reveals iron deficiency anemia with decreased values of hemoglobin, hematocrit, MCV, and serum ferritin and increased [hindawi.com]

Laboratory tests Laboratory examinations typically reveal iron deficiency anemia with decreased values of hemoglobin, hematocrit, mean corpuscular volume, serum iron and ferritin [ncbi.nlm.nih.gov]

Myelodysplasia

[…] the hematocrit, but not the WBC count. [clevelandclinicmeded.com]

Unlike the target hematocrit of under 45% for PV, a target platelet count does not exist for ET. [clevelandclinicmeded.com]

A randomized study showed that hydroxyurea decreased the risk of thrombosis in high-risk patients who have ET from 24% to less than 4% ( P =.003), compared with no treatment [clevelandclinicmeded.com]

Multiple Myeloma

[…] in serum globulin and an increase in hematocrit but no difference in survival compared with a placebo. 36 In another study, prednisone, in a single dose of 200 mg every other [doi.org]

[…] multiple myeloma. 35 Corticosteroids were first tested by Maas, who determined in a placebo-controlled double-blind trial that prednisone as a single agent produced significant decreases [doi.org]

Systemic Lupus Erythematosus

hematocrit with or without hemoptysis, with diagnosis being confirmed on bronchoalveolar lavage. [journals.lww.com]

[…] potentially severe complication occurring in 1%–5% of SLE patients and carrying a 50% mortality. 53 It should be suspected in any case of new dyspnea, ground-glass opacities, or decreasing [journals.lww.com]

[…] potentially severe complication occurring in 1%–5% of SLE patients and carrying a 50% mortality.53 It should be suspected in any case of new dyspnea, ground-glass opacities, or decreasing [journals.lww.com]

Sjögren Syndrome

Based on increased or decreased numbers in these counts, underlying medical conditions may be present; typically, autoimmune disease is represented by low white blood cell [en.wikipedia.org]

[…] count[edit] A test taking measurements on maturity levels, count, and size of blood cells.[27][36] Targeted cells include: red blood cells, white blood cells, hemoglobin, hematocrit [en.wikipedia.org]

Megaloblastic Anemia

Hematocrit – decreased3. RBC count – decreased/normal4. MCV - >100fl ( normal 82-98fl)5. MCH –increased6. MCHC – NORMAL7. Reticulocytopenia.8. [slideshare.net]

Hematocrit and hemoglobin may be decreased in cases of active bleeding. [scielo.br]

Clinical examination was significant only for pallor, and decreased air entry bilaterally consistent with bilateral pleural effusion on chest X-ray (Figure 1). [esciencecentral.org]