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134 Possible Causes for Hematocrit Decreased, Hepatomegaly, Reticulocytes Increased

  • Primary Myelofibrosis

    The patient, a 62-year-old female, having had primary myelofibrosis for 13 years and a splenectomy 4 years before, was admitted because of high fever, hepatomegaly, thrombocythemia[ncbi.nlm.nih.gov] The percentage of reticulocytes is mildly increased but may vary widely in a given case.[patient-help.com] […] the hematocrit, but not the WBC count.[clevelandclinicmeded.com]

  • Autoimmune Hemolytic Anemia

    […] hepatitis B virus, drug usage or cholestatic syndrome and in around 40% of cases its etiology will be defined as autoimmune. 22 One patient from the present sample developed hepatomegaly[scielo.br] Over the course of the next 5 days, the Hb and Hct decreased to 4.1 g/dL and 12%, respectively, direct bili increased to 12.3 mg/day, reticulocytes slightly increased to 0.9%[ncbi.nlm.nih.gov] The differential white blood count shows a decrease in most types of cells but not lymphocytes .[labtestsonline.org]

  • Cooley's Anemia

    Abdominal imaging such as ultrasound scanning, MRI, or CT may show gallstones, liver cirrhosis, and hepatomegaly.[symptoma.com] Children may develop dramatic, often life threatening drops in hematocrit with reticulocyte counts of nearly zero.[de.slideshare.net] The differential white blood count shows a decrease in most types of cells but not lymphocytes .[labtestsonline.org]

  • Sickle Cell Disease

    Additional autopsy findings included cardiomegaly with a heart weight of 450 gm (312 78), right atrial and right ventricular chamber dilatation, and hepatomegaly with a liver[ncbi.nlm.nih.gov] With each course, fetal reticulocytes increased within 48-72 h, peaked in 7-11 d, and fell by 18-21 d.[doi.org] (p 0.001), while hemoglobin and hematocrit remained stable.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    Pathological findings include systemic venous or portal thrombosis, normoblastic bone marrow hyperplasia, hepatomegaly with necrosis, hemosiderosis, and massive iron deposits[whonamedit.com] Erythrocytes fractionated by centrifugation revealed increased glycolytic enzyme activities of hexokinase, G3PD, PGK, TPI, PK, LDH, G6PD, and 6PGD in the reticulocyte-rich[pediatrics.aappublications.org] […] characterized by episodes of hemolytic anemia, hemoglobinuria (chiefly at night), pallor, icterus or bronzing of the skin, a moderate degree of splenomegaly, and sometimes hepatomegaly[medical-dictionary.thefreedictionary.com]

  • Gaucher Disease

    A physical examination revealed obvious hypoevolutism and hepatomegaly, and laboratory tests and imaging examinations showed severe pulmonary interstitial fibrosis, infection[ncbi.nlm.nih.gov] After 4years of ERT, therapeutic goals for thrombocytopenia and splenomegaly had been achieved in 100% of patients; goals for anemia and hepatomegaly had been achieved in[ncbi.nlm.nih.gov] Radiographically, hepatomegaly and splenomegaly respond more rapidly than skeletal changes.[radiopaedia.org]

  • Familial Myelofibrosis

    In case of hepatomegaly, the liver extends to more than 3 cm below the right costal margin of the newborn.[symptoma.com] Cladribine This purine analogue, previously known as 2‐chlorodeoxyadenosine, has been shown to reduce clinically significant post‐splenectomy hepatomegaly and post‐splenectomy[onlinelibrary.wiley.com] At the same time, the number of immature cells in peripheral blood is increased.[symptoma.com]

  • Glycogen Storage Disease Type 1

    The syndrome results in hepatomegaly secondary to glycogen accumulation, glucose and galactose intolerance, fasting hypoglycaemia, a characteristic proximal tubular nephropathy[en.wikipedia.org] Abstract A male child presented at 5 months of age with vomiting, diarrhoea, hypoglycaemia and hepatomegaly.[ncbi.nlm.nih.gov] The molecular pathways involved in liver pathologies, including steatosis, hepatomegaly (glycogenic hepatopathy) and the development of liver tumours are also compared.[ncbi.nlm.nih.gov]

  • Hodgkin Lymphoma

    The presenting feature common in all cases was superficial lymphadenopathy followed by hepatomegaly in 17 (20%) cases and splenomegaly in 16 (19%).[ncbi.nlm.nih.gov] Abdomen: Abdominal enlargement may be noted with splenomegaly or hepatomegaly.[symptoma.com] The nodes may also feel rubbery and swollen when examined Splenomegaly: enlargement of the spleen occurs in about 30% of people with Hodgkin's lymphoma Hepatomegaly: enlargement[slideshare.net]

  • Chronic Myeloid Leukemia

    Hepatomegaly also occurs, although less commonly than splenomegaly. Hepatomegaly is usually part of the extramedullary hematopoiesis occurring in the spleen.[emedicine.medscape.com] Low-grade fever and excessive sweating Elevated white blood cell (WBC) count Splenomegaly Decreased appetite and food intake Left upper quadrant abdominal pain from splenomegaly Hepatomegaly[symptoma.com] Poor-prognosis characteristics include the following clinical and laboratory factors: Older age Symptomatic presentation Poor performance status African-American descent Hepatomegaly[emedicine.medscape.com]

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