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176 Possible Causes for Hematocrit Decreased, Hepatosplenomegaly, Pallor

  • Familial Myelofibrosis

    The illness presented with pallor, haemorrhagic symptoms, and hepatosplenomegaly, and the blood picture was that of pancytopenia and leucoerythroblastosis.[ncbi.nlm.nih.gov] Hepatosplenomegaly may cause irritability, feeding difficulties, loss of appetite and weight. Children may complain about abdominal pain.[symptoma.com] The illness presented with pallor, haemorrhagic symptoms, and hepatosplenomegaly, and the blood picture was that of pancytopenia and leucoerythroblastosis.[ncbi.nlm.nih.gov]

  • Leukemia

    An additional eight features were present in a third to a half of children: recurrent infections (49%), fatigue (46%), limb pain (43%), hepatosplenomegaly (42%), bruising[ncbi.nlm.nih.gov] Stage I Stage I CLL is characterized by absolute lymphocytosis with lymphadenopathy without hepatosplenomegaly, anemia, or thrombocytopenia.[web.archive.org] Physical examination reveals pallor and multiple ecchymoses on his arms, legs, and trunk.[doi.org]

  • Nephroblastoma

    Non-specific symptoms are present in less than 1/3 children: subfebrility, weakness, pallor, loss of appetite constipation, abdominal pain 10–30 % patients develop micro or[telemedicina.med.muni.cz] 41.7 %) and hematocrit (13.9 %).[ncbi.nlm.nih.gov] The most frequently decreased lymphocyte subpopulation was CD8 (15.5%).[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    The main clinical manifestations of PMF are anemia, bleeding, hepatosplenomegaly, fatigue, and fever.[ncbi.nlm.nih.gov] Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy[orpha.net] Skin pallor (caused by anemia) may also be noticeable.[aoporphan.com]

  • Multiple Myeloma

    The presenting problem was proteinuria in five patients, thyromegaly in three patients, and hepatosplenomegaly in one patient.[jamanetwork.com] A physical examination revealed generalized pallor and dehydration but no signs of abdominal peritoneal irritation.[ncbi.nlm.nih.gov] […] they reported a progression-free survival of 2, 10 and 46% for the presence of none, one or two risk factors, respectively at 5 years in MGUS. 17 The age, sex, presence of hepatosplenomegaly[doi.org]

  • Waldenstrom Macroglobulinemia

    Most commonly it presents with cytopenia, hepatosplenomegaly, lymphadenopathy, constitutional symptoms, and hyperviscosity syndrome.[ncbi.nlm.nih.gov] However, the patient also reported a one-year history of painful pallor in his digits; therefore, further rheumatologic workup for presumed Raynaud’s phenomenon was requested[the-rheumatologist.org] Median serum IgM decreased from 3670 to 1590 mg/dL (P .001), whereas median hematocrit rose from 33.0% to 37.6% (P .004) at best response.[ncbi.nlm.nih.gov]

  • Acute Myelocytic Leukemia

    In all three patients, radionuclide imaging with technetium-99m sulfur colloid showed hepatosplenomegaly, decreased liver uptake, and increased splenic activity.[ncbi.nlm.nih.gov] The main clinical picture consists of a short time period with pallor, fatigue, fever, infections and hemorrhages. Presence of all these features is not compulsory.[orpha.net] On exam, he has bilateral submandibular lymphadenopathy and hepatosplenomegaly. CBC demonstrates decreased RBCs and mature WBCs.[step1.medbullets.com]

  • Chronic Lymphocytic Leukemia

    III Lymphocytosis; lymphadenopathy; hepatosplenomegaly, anemia IV Lymphocytosis, lymphadenopathy; hepatosplenomegaly, thrombocytopenia anemia CHRONIC LYMPHOCYTIC LEUKEMIA[medical-dictionary.thefreedictionary.com] CASE PRESENTATION: We describe a case of a 77-year-old man who presented with fatigue, pallor and lower limb pain and weakness.[ncbi.nlm.nih.gov] […] examination In addition to localized or generalized lymphadenopathy, patients may manifest the following: Splenomegaly (30-54% of cases) Hepatomegaly (10-20% of cases) Petechiae Pallor[emedicine.medscape.com]

  • Thalassemia

    They have severe anemia and hepatosplenomegaly. Untreated children have severe failure to thrive and shortened life expectancy.[meddean.luc.edu] Clinical description Onset is during infancy with severe anemia, failure to thrive and progressive pallor.[orpha.net] Some infants become progressively pale (pallor).[rarediseases.org]

  • Autoimmune Hemolytic Anemia

    CASE CHARACTERISTICS: A 7-month-old boy, presented with prolonged fever, erythematous rash, severe pallor and hepatosplenomegaly.[ncbi.nlm.nih.gov] Computed tomography (CT) of the chest, abdomen and pelvis was remarkable for hepatosplenomegaly.[dx.doi.org] CASE PRESENTATION: An otherwise seemingly normal girl, who had developed limping at the age of 11 months old, referred to Namazi Hospital, Shiraz, Iran, due to pallor and[ncbi.nlm.nih.gov]

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