Create issue ticket

76 Possible Causes for Hematocrit Decreased, Hypercellular Bone Marrow, Reticulocytes Increased

  • Hereditary Spherocytosis

    Reticulocyte count: Increased Treatment: Splenectomy is indicated for moderate to severe cases, but not mild cases.[medical-labs.net] A complete blood count (CBC) may show increased reticulocytes, a sign of increased red blood cell production, and decreased hemoglobin and hematocrit.[en.wikipedia.org] Reticulocytes decreased to 0%. Spherocytosis was present on the peripheral blood smear.[bmcresnotes.biomedcentral.com]

  • Autoimmune Hemolytic Anemia

    Over the course of the next 5 days, the Hb and Hct decreased to 4.1 g/dL and 12%, respectively, direct bili increased to 12.3 mg/day, reticulocytes slightly increased to 0.9%[ncbi.nlm.nih.gov] Subsequently, the patient underwent a bone marrow biopsy that showed a hypercellular marrow with erythroid hyperplasia, but no evidence of dysplasia or lymphoma.[jmedicalcasereports.com] The differential white blood count shows a decrease in most types of cells but not lymphocytes .[labtestsonline.org]

  • Paroxysmal Nocturnal Hemoglobinuria

    Erythrocytes fractionated by centrifugation revealed increased glycolytic enzyme activities of hexokinase, G3PD, PGK, TPI, PK, LDH, G6PD, and 6PGD in the reticulocyte-rich[pediatrics.aappublications.org] These patients tend to have a normocellular to hypercellular bone marrow with erythroid hyperplasia, an elevated reticulocyte count, a large population of PNH cells (usually[bloodjournal.hematologylibrary.org] Blockade of terminal complement components presumably prolongs the survival of type III erythrocytes (since there was no simultaneous increase in reticulocytes), which are[nejm.org]

  • Cooley's Anemia

    Children may develop dramatic, often life threatening drops in hematocrit with reticulocyte counts of nearly zero.[de.slideshare.net] The differential white blood count shows a decrease in most types of cells but not lymphocytes .[labtestsonline.org] This "aplastic crisis" often requires emergent transfusion support The effectiveness of present effective strategies has increased the life spans of patients with thalassaemia[de.slideshare.net]

  • Sickle Cell Disease

    With each course, fetal reticulocytes increased within 48-72 h, peaked in 7-11 d, and fell by 18-21 d.[doi.org] (p 0.001), while hemoglobin and hematocrit remained stable.[ncbi.nlm.nih.gov] On her third day of admission, due to hemoglobin (Hb) value of 6.9 g/dL with increase in reticulocytes, the patient was transfused with one unit of compatible leukodepleted[ncbi.nlm.nih.gov]

  • Congenital Hemolytic Anemia

    After partial splenectomy, children overall had decreased transfusion requirements, increased hematocrits, decreased bilirubin levels, decreased reticulocyte counts, and elimination[ncbi.nlm.nih.gov] As a result of splenectomy, reticulocyte counts often increase and transfusion needs are reduced.[orpha.net] Laboratory studies show evidence not only of many spherocytes but also increased numbers of reticulocytes (young red blood cells), hyperbilirubinemia (increased blood levels[medicinenet.com]

  • Chronic Myeloid Leukemia

    marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] Because of such abnormal shapes, these cells are destroyed before releasing into the peripheral blood circulation, leading to cytopenias and hypercellular bone marrow.[lecturio.com] marrow hypercellularity, granulocyte proliferation, and decrease in erythroid precursors.[doi.org]

  • Chronic Phase of Chronic Myeloid Leukemia

    marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] A bone marrow biopsy and aspiration demonstrated a hypercellular marrow with no other significant morphologic abnormalities.[hematologyandoncology.net] marrow Early myeloid cells (eg, myeloblasts, myelocytes, metamyelocytes, nucleated red blood cells) Bone marrow findings Ph chromosome (a reciprocal translocation of chromosomal[emedicine.medscape.com]

  • Pyruvate Kinase Deficiency

    Char10C mice also display a reduction in anemia phenotypes associated with the PklrG338D mutation including decreased splenomegaly, decreased circulating reticulocytes, increased[ncbi.nlm.nih.gov] As a result of splenectomy, reticulocyte counts often increase and transfusion needs are reduced.[orpha.net] Hemoglobin measurement also shows a decrease to 6–12g/dL where normal ranges from 12–16.5g/dL.[themedicalbiochemistrypage.org]

  • Primary Myelofibrosis

    The percentage of reticulocytes is mildly increased but may vary widely in a given case.[patient-help.com] A biopsy of the lytic lesion was done, revealing hypercellular bone marrow with hyperplastic granulopoiesis associated with megakaryocytic proliferation and atypia, accompanied[ncbi.nlm.nih.gov] […] the hematocrit, but not the WBC count.[clevelandclinicmeded.com]

Similar symptoms