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10 Possible Causes for Hematocrit Decreased, Intermittent Jaundice, Uric Acid Increased

  • Hereditary Spherocytosis

    A complete blood count (CBC) may show increased reticulocytes, a sign of increased red blood cell production, and decreased hemoglobin and hematocrit.[] Abstract Hereditary spherocytosis is an autosomal dominant congenital hemolytic anemia due to defect in RBC membrane protein that commonly presents with intermittent jaundice[] Reticulocytes decreased to 0%. Spherocytosis was present on the peripheral blood smear.[]

  • Sickle Cell Disease

    (p 0.001), while hemoglobin and hematocrit remained stable.[] Jaundice Fatigue Swollen hands and feet The severity of these symptoms can vary significantly for each individual with the disease, according to the specific characteristics[] Each individual with SCD is unique, but the most common features are: Anemia (may cause fatigue and decreased endurance), reticulocytosis, and jaundice Intermittent acute[]

  • Hepatorenal Syndrome

    Hemoglobin, hematocrit, and plasma protein concentrations decreased by 18% during HWI.[] Wui-Chiang Lee, Han-Chieh Lin, Ming-Chih Hou, Hsiao-Yi Lin, Fa-Yauh Lee, Sun-Sang Wang, Full-Young Chang and Shou-Dong Lee , Serum Uric Acid Levels in Patients With Cirrhosis[] Severe circulatory dysfunction (mean arterial pressure usually is 70 mm Hg) and very low systemic vascular resistance. • Severe liver disease, with jaundice, coagulopathy,[]

  • Primary Biliary Cirrhosis

    Twenty four hour urine demonstrated a low renal fractional tubular reabsorption of phosphate, increased fractional excretion of uric acid and generalized aminoaciduria.[] Jaundice (30 -70 %) -Acute cholangitis - relatively rare (5-25%) symptoms secondary to biliary cirrhosis: -portal HTN -liver failure Advanced liver disease -ascites, variceal[] Reddy AN, Grosberg SJ, Wapnick S: Intermittent cholestatic jaundice and nonmetastatic prostatic carcinoma. Arch Intern Med 1977;137:1616–1618.[]

  • Propionic Acidemia

    […] elevated Ketotic hyperglycinemia Ketotic hypoglycemia Hypoketotic hypoglycemia Serum ammonia Increased creatinine kinase Increased serum uric acid Decreased serum uric acid[] […] or hepatomegalyLethargyComa (particularly intermittent)Unexplained hemorrhageFamily history of neonatal deaths, or of similar illness, especially in siblingsParental consanguinitySepsis[] […] or hepatomegaly Lethargy Coma (particularly intermittent) Unexplained hemorrhage Family history of neonatal deaths, or of simila r illness, especially in siblings Parental[]

  • Wilson Disease

    acid levels Tissue sample through surgical biopsy of the liver show increased levels of copper (greater than 250 mcg/g dry weight) Physical examination may show signs of[] A 15 year old girl presented to an internal medicine ward with a two day history of jaundice and intermittent, high grade fever.[] Wilson disease levels may be normal) Serum copper levels of less than 80 mcg/dL (in spite of copper deposits in tissue) Urine copper levels of greater than 100 mg Low serum uric[]

  • Renal Impairment

    There were no reports of anemia, and no patients were discontinued due to decreased hematocrit.[] Abstract Benign recurrent intrahepatic cholestasis (BRIC) is a rare autosomal recessive condition characterized by intermittent episodes of pruritus and jaundice that may[] […] in gut motility; hematocrit of CR , medical history, physical examination, vital signs, clinical laboratory testing, and an electrocardiogram (ECG).[]

  • Hexokinase Deficiency

    Maintain normal hematocrit (40 to 45 mL/100 mL) and platelet counts. Studies demonstrate that cerebral blood flow is decreased even if the hematocrit is mildly elevated.[] Uric Acid), and the patient presents Hyperuricemia.[] Intermittent jaundice and premature pigment gallstones are common. Splenomegaly is characteristic (palpable in 75% to 80% of cases).[]

  • Hemolytic Anemia due to a Disorder of Glycolytic Enzymes

    As shown in Table 1, hemolytic crisis in WD patients was evident from increased plasma Hb levels, decreased hematocrit, and anemia.[] jaundice and episodes of red/ dark urine Venous thrombosis in unusual locations (e.g., hepatic, cerebral, abdominal veins) Vasoconstriction : headache, pulmonary hypertension[] However, inosine, which is a naturally occurring substance, increases plasma uric acid levels ( 38 ).[]

  • Familial Pseudohyperkalemia

    […] in plasma volume without change in red blood cell mass so that the erythrocytes become more concentrated (elevated hematocrit), which may be an acute transient or a chronic[] Microalbuminuria Increased WBC count Increased C-reactive protein Increased fibrinogen Increased pro inflammatory cytokines Increased uric acid Type 2 DM Fatty Liver HTN and[] Patients with HC1 may present later in life with macrocytosis, anemia, reticulocytosis, intermittent jaundice, gallstones, a palpable spleen tip, stomatocytosis, or because[]

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