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97 Possible Causes for Hematocrit Decreased, Mean Corpuscular Volume Increased, Reticulocytes Increased

  • Congenital Dyserythropoietic Anemia

    On this treatment, hemoglobin and reticulocytes increased and transfusions became unnecessary.[ncbi.nlm.nih.gov] Following delivery the infant had serial blood counts performed over a 6-week period, which noted a steady decrease in her hematocrit to 16%.[bloodjournal.org] The reticulocyte count was always low, in spite of the increased erythropoietic activity. A beta-thalassemia trait inherited from the mother was demonstrated.[ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    Over the course of the next 5 days, the Hb and Hct decreased to 4.1 g/dL and 12%, respectively, direct bili increased to 12.3 mg/day, reticulocytes slightly increased to 0.9%[ncbi.nlm.nih.gov] Reticulocyte counts are usually elevated, and an increased MCV (mean corpuscular volume) (greater than 100 fl) can be seen, due to the larger size of reticulocytes in comparison[cancertherapyadvisor.com] The differential white blood count shows a decrease in most types of cells but not lymphocytes .[labtestsonline.org]

  • Cold Agglutinin Disease

    Typical bloodwork results would show: decreased hemoglobin (due to the red cell lysis) increased reticulocyte count (reflecting the marrow kicking red cell production into[transfusion.ca] The MCHC and MCH values will be increased due to decreased hematocrit and RBC count. Other causes of invalid red cell indices have to be ruled out.[keralamedicaljournal.com] The mean corpuscular volume (MCV) is elevated because of reticulocytosis, as well as agglutination of the RBCs.[web.archive.org]

  • Congenital Hemolytic Anemia

    After partial splenectomy, children overall had decreased transfusion requirements, increased hematocrits, decreased bilirubin levels, decreased reticulocyte counts, and elimination[ncbi.nlm.nih.gov] Mean corpuscular hemoglobin concentration (MCHC) is increased (35-38%) in approximately 50% of patients.[clinicaladvisor.com] As a result of splenectomy, reticulocyte counts often increase and transfusion needs are reduced.[orpha.net]

  • Primary Myelofibrosis

    The percentage of reticulocytes is mildly increased but may vary widely in a given case.[patient-help.com] […] the hematocrit, but not the WBC count.[clevelandclinicmeded.com] Unlike the target hematocrit of under 45% for PV, a target platelet count does not exist for ET.[clevelandclinicmeded.com]

  • Paroxysmal Nocturnal Hemoglobinuria

    Erythrocytes fractionated by centrifugation revealed increased glycolytic enzyme activities of hexokinase, G3PD, PGK, TPI, PK, LDH, G6PD, and 6PGD in the reticulocyte-rich[pediatrics.aappublications.org] Blockade of terminal complement components presumably prolongs the survival of type III erythrocytes (since there was no simultaneous increase in reticulocytes), which are[nejm.org] Intravascular hemolysis with moderate to severe anemia, an elevated reticulocyte count, and up to a 10-fold increase in lactate dehydrogenase (LDH) is common in classical[bloodjournal.org]

  • Familial Myelofibrosis

    At the same time, the number of immature cells in peripheral blood is increased.[symptoma.com] Immature granulocytes, reticulocytes, normoblasts, and dacrocytes can be observed under the microscope.[symptoma.com]

  • Gaucher Disease

    If you or a loved one has been diagnosed with Gaucher disease (pronounced go-SHAY), know that you are not alone. Gaucher disease affects up to 1 in 40,000 live births in the general population. What Is Gaucher Disease? Gaucher disease is one of the most common lysosomal storage disorders and results from not[…][gaucherdisease.org]

  • Malaria

    Congenital malaria is usually defined as the detection of asexual forms of Plasmodium spp. in a blood sample of a neonate during perinatal age if there is no possibility of postpartum infection by a mosquito bite. The incidence of congenital malaria is highly variable and seems related to several factors, such as[…][ncbi.nlm.nih.gov]

  • Acute Monocytic Leukemia

    Abstract Myeloid histocytes of dendritic cells (DCs), Langerhans cells (LCs), and macrophages in varied tissues, as leukemic blasts in acute monoblastic and monocytic leukemia (AML-M5a and M5b), are derived from monocyte progenitors in bone marrow. Based on DC induction from hematopoietic stem cells, myeloid[…][ncbi.nlm.nih.gov]

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