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56 Possible Causes for Hematocrit Decreased, Red Blood Cell Distribution Width Increased

  • Iron Deficiency Anemia

    […] high red blood cell distribution width, reflecting an increased variability in the size of red blood cells.A low mean corpuscular volume also appears during the course of[en.wikipedia.org] ; normal unless infection is present Cells are iron deficient; as hematocrit falls below 30%, hypochromic microcytic cells appear, followed by a decrease in MCV White blood[medical-dictionary.thefreedictionary.com] This is reflected in the red blood cell distribution width (RDW); thus, the earliest evidence of the development of an iron-deficient erythropoiesis is seen in the peripheral[emedicine.medscape.com]

  • Myelodysplasia

    […] the hematocrit, but not the WBC count.[clevelandclinicmeded.com] Response The labeled indication for the treatment of anemia related to chemotherapy is to decrease the need for transfusions in patients who will be receiving concomitant[web.archive.org] Unlike the target hematocrit of under 45% for PV, a target platelet count does not exist for ET.[clevelandclinicmeded.com]

  • Megaloblastic Anemia

    […] variation in the size of RBCs (red cell distribution width, RDW) A blood smear may reveal RBCs that are smaller and paler than normal as well as RBCs that vary in size (anisocytosis[labtestsonline.org] Hematocrit – decreased3. RBC count – decreased/normal4. MCV - 100fl ( normal 82-98fl)5. MCH –increased6. MCHC – NORMAL7. Reticulocytopenia.8.[slideshare.net] Clinical examination was significant only for pallor, and decreased air entry bilaterally consistent with bilateral pleural effusion on chest X-ray (Figure 1).[esciencecentral.org]

  • Thalassemia

    blood cell distribution width High Normal; occasionally high Normal Ferritin Low Normal Normal Mentzer index for children (MCV/red blood cell count) 13 13 13 Hb electrophoresis[aafp.org] Though some overlap with α-thalassemia carrier states exists, individuals with iron deficiency anemia show a marked increase in red blood cell distribution width (RDW), a[ncbi.nlm.nih.gov] Normal (may have reduced HbA2) Increased HbA2, reduced HbA, and probably increased HbF Adults: normal Newborns: may have HbH or Hb Bart's Table 3.[aafp.org]

  • Sickle Cell Disease

    (p 0.001), while hemoglobin and hematocrit remained stable.[ncbi.nlm.nih.gov] Ferritin levels on chronic patients decreased 54%.[ncbi.nlm.nih.gov] Mean decrease in sickle hemoglobin levels was higher in automated-red blood cell exchange (p 0.001) and permitted a higher sickle hemoglobin level decrease per volume removed[ncbi.nlm.nih.gov]

  • Iron Deficiency

    Average size of RBCs (MCV) — may be decreased Average amount of Hb in RBCs (MCH) — may be decreased Increased variation in the size of RBCs (red cell distribution width (RDW[labtestsonline.org.au] ; normal unless infection is present Cells are iron deficient; as hematocrit falls below 30%, hypochromic microcytic cells appear, followed by a decrease in MCV White blood[medical-dictionary.thefreedictionary.com] This is reflected in the red blood cell distribution width (RDW); thus, the earliest evidence of the development of an iron-deficient erythropoiesis is seen in the peripheral[emedicine.com]

  • Anemia

    […] variation in the size of RBCs (red cell distribution width, RDW) A blood smear may reveal RBCs that are smaller and paler than normal as well as RBCs that vary in size (anisocytosis[labtestsonline.org] Throughout fetal life, erythrocytes decrease in size and increase in number: hematocrit increases from 30% to 40% during the second trimester to 50% to 63% at term.[pedsinreview.aappublications.org] We observed a significant increase in hematocrit and transferrin saturation and a decrease in the percentage of hypochromic red cells and ferritin levels at the end of the[doi.org]

  • Vitamin B12 Deficiency

    […] in serum vitamin B 12 and the decline in hematocrit.[aafp.org] The mean decrease after 4 months of treatment was highly significant in each group ( P .005).[bloodjournal.org] […] pernicious anemia who had not received maintenance vitamin B 12 injections for months to years, the rise of methylmalonic acid and homocysteine levels was found to precede the decrease[aafp.org]

  • Hereditary Spherocytosis

    FBC shows raised MCHC and increased red cell distribution width.[patient.info] A complete blood count (CBC) may show increased reticulocytes, a sign of increased red blood cell production, and decreased hemoglobin and hematocrit.[en.wikipedia.org] Reticulocytes decreased to 0%. Spherocytosis was present on the peripheral blood smear.[bmcresnotes.biomedcentral.com]

  • Pernicious Anemia

    […] variation in the size of RBCs (red cell distribution width, RDW) A blood smear may reveal RBCs that are smaller and paler than normal as well as RBCs that vary in size (anisocytosis[labtestsonline.org] […] in serum vitamin B 12 and the decline in hematocrit.[aafp.org] The differential white blood count shows a decrease in most types of cells but not lymphocytes.[labtestsonline.org]

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