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169 Possible Causes for Hematocrit Decreased, Reticulocytes Increased, Thrombocytopenia

  • HELLP Syndrome

    Despite delivery of the fetus, her condition deteriorated over 3-4 days with high-grade fever, worsening thrombocytopenia and anaemia requiring transfusion support.[ncbi.nlm.nih.gov] Blood smears have shown contracted red cells w/ spicula, polychromatic red cells, and increased reticulocyte counts.[physio-pedia.com] The laboratory investigations before death revealed evidence of hemolysis, which is decreased hematocrit, elevated lactate dehydrogenase (865 U/L), and low platelet count[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    Six weeks later, he developed grade 4 thrombocytopenia and grade 3 anemia.[ncbi.nlm.nih.gov] The percentage of reticulocytes is mildly increased but may vary widely in a given case.[patient-help.com] […] the hematocrit, but not the WBC count.[clevelandclinicmeded.com]

  • Paroxysmal Nocturnal Hemoglobinuria

    This case raises caution for heparin-induced thrombocytopenia in paroxysmal nocturnal hemoglobinuria.[ncbi.nlm.nih.gov] Erythrocytes fractionated by centrifugation revealed increased glycolytic enzyme activities of hexokinase, G3PD, PGK, TPI, PK, LDH, G6PD, and 6PGD in the reticulocyte-rich[pediatrics.aappublications.org] The combination of thrombosis, splenomegaly, and thrombocytopenia (TST) is challenging because anticoagulants are indicated but thrombocytopenia may increase the bleeding[ncbi.nlm.nih.gov]

  • Sickle Cell Disease

    Patients should be monitored for leukopenia and thrombocytopenia. Complications from long-term usage are not yet known. Efficacy in children has not been proven.[symptoma.com] With each course, fetal reticulocytes increased within 48-72 h, peaked in 7-11 d, and fell by 18-21 d.[doi.org] (p 0.001), while hemoglobin and hematocrit remained stable.[ncbi.nlm.nih.gov]

  • Gaucher Disease

    KEYWORDS: GBA gene mutation; Gaucher cells; thrombocytopenia; type 1 Gaucher disease[ncbi.nlm.nih.gov] Type 1 Gaucher disease At onset, patients with type 1 Gaucher disease commonly present with painless splenomegaly, anemia, or thrombocytopenia.[emedicine.medscape.com] Gaucher disease is a common inborn error of metabolism leading to widespread chronic inflammation and often thrombocytopenia.[ncbi.nlm.nih.gov]

  • Atypical Hemolytic Uremic Syndrome

    From Wikidata Jump to navigation Jump to search complement deficiency that is characterized by mechanical hemolytic anemia, thrombocytopenia, and renal dysfunction atypical[wikidata.org] Lactate dehydrogenase was increased to 1084 U/L ( 460 U/L), reticulocyte count was 8.9%, and haptoglobin was less than 0.4 g/L (.1-.3 g/L).[doi.org] hematocrit and hemoglobin and thrombocytopenia ; schistocytes on peripheral blood smears, elevated LDH, low haptoglobin, elevated indirect bilirrubin, elevated reticulocytes[biomed.uninet.edu]

  • Chronic Myeloid Leukemia

    […] by imatinib, it was intriguing to analyze the role of platelet-derived growth factor receptor-α in relation to imatinib treatment in the development of imatinib-induced thrombocytopenia[ncbi.nlm.nih.gov] Immune thrombocytopenia (ITP) was also diagnosed in this patient following the detection of antiplatelet autoantibodies.[ncbi.nlm.nih.gov] […] hemorrhage should be considered as a possible complication in patients with atypical chronic myeloid leukemia, even in chronic phase, if they have hyperleukocytosis and thrombocytopenia[ncbi.nlm.nih.gov]

  • Familial Myelofibrosis

    Blood counts generally reveal normocytic, normochromic anemia, leukopenia, and thrombocytopenia.[symptoma.com] , thrombocytosis, increased LDH Prognostic factors Histologic stage at diagnosis (prefibrotic versus fibrotic) Adverse factors include age 70 years, anemia (Hb 10 g/dL), thrombocytopenia[pathologyoutlines.com] Responses were also reported for anaemia (22%) and thrombocytopenia (50%).[onlinelibrary.wiley.com]

  • Chronic Phase of Chronic Myeloid Leukemia

    Transfusion of blood products is indicated to compensate for anemia and thrombocytopenia.[symptoma.com] Thrombocytopenia, hepatotoxicity, hyperbilirubinemia and hyperglycemia were the most common hematologic and non-hematologic adverse events (AEs).[haematologica.org] The accelerated phase is characterized by complications secondary to the suppression of the other cell lines ( thrombocytopenia, anemia, recurrent infections).[amboss.com]

  • Acute Monocytic Leukemia

    Awareness of this laboratory artifact in secondary acute monocytic leukemia with tumor lysis syndrome is important so that potential life-threatening thrombocytopenia is not[ncbi.nlm.nih.gov] An 86-year-old man presented with acute hepatic failure, worsening thrombocytopenia, and anemia having been diagnosed and managed expectantly with cytogenetically normal RAEB[ncbi.nlm.nih.gov] Bone marrow suppression is a common symptom of chemotherapy, which might lead to anemia, neutropenia, and thrombocytopenia.[news-medical.net]

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