Possible Causes for Hematocrit Increased Decreased Oxygen Carrying Capacity Increased Hematocrit can also cause the blood to clot which can block blood vessels leading to heart attack or stroke. [online.science.psu.edu] Causes of High Hematocrit Levels Increased size of Red Blood Cells causes an increase in Hematocrit Level. [the-healthcare.org] HCT low and high: Elevated In cases of dengue fever, a high hematocrit is a danger sign of an increased risk of dengue shock syndrome. [nurse-anesthesia.org] Stress Polycythemia Spurious polycythemia is characterized by increased hematocrit and normal or decreased red blood cell (RBC) total mass. [doctor-clinic.org] Characterized by increased hematocrit and normal or decreased red blood cell (RBC) total mass, spurious polycythemia results from decreasing plasma volume and subsequent hemoconcentration [nursekey.com] Even modest increases in the hemoglobin/hematocrit level can have a major impact on whole blood viscosity. [mhmedical.com] Secondary Polycythemia increase in blood volume, and only severe increases in hematocrit are detrimental. [ncbi.nlm.nih.gov] Diagnostic tests Laboratory results for secondary polycythemia include: increased RBC mass, with increased hematocrit, hemoglobin levels, mean corpuscular volume, and mean [doctor-clinic.org] […] hemoglobin and an alteration of the overall ratio of blood cells to blood fluids, an increased hematocrit. [symptoma.com] Polycythemia […] in hemoglobin or hematocrit). [aoporphan.com] Polycythemia is an abnormal increase in red blood cell mass, defined in neonates as a venous hematocrit ≥ 65%; this increase can lead to hyperviscosity with sludging of blood [merckmanuals.com] Blood analysis The number of erythrocytes, together with the hemoglobin and hematocrit results, are elevated (hemoglobin: blood pigment, hematocrit: cellular components of [aoporphan.com] Polycythemia Neonatorum The abnormal increase in hematocrit increases the risk of hyperviscosity, microcirculatory hypoperfusion, and multisystem organ dysfunction [3]. [itmedicalteam.pl] Hemoglobin and hematocrit appear increased but other CBC parameters such as white blood cell and platelet counts are normal. [openeducationalberta.ca] However, in case <strong>of</strong> increased hematocrite values <strong>the</strong> diagnostic test has to be confirmed using venous sample. Delete template? [yumpu.com] Erythrocytosis […] of blood increases exponentially with an increase in hematocrit. [haematologica.org] Erythrocytosis results when there is an increased red cell mass in the circulation and thus also hemoglobin and hematocrit are increased. [worldcat.org] […] with no increase in serum erythropoietin (Epo) level at the time of RCC relapse. [ncbi.nlm.nih.gov] Polycythemia Vera Patients are often asymptomatic, and it is detected only when routine blood work shows increased hematocrit or hemoglobin. [clinicaladvisor.com] Symptoms develop from an enlarged blood volume and increased hematocrit level; venous thrombotic episodes may occur. 2. Complications of severe arterial disease [jamanetwork.com] […] in hemoglobin or hematocrit). [aoporphan.com] Familial Polycythemia […] red blood cell mass,Increased hematocrit,Increased hemoglobin,Normal oxygen affinity of hemoglobin,Hypersensitivity of erythroid colony-forming units to erythropoietin,(EPO [datapunk.net] A similar increase in hematocrit can be achieved with erythropoietin injections, which can increase maximal exercise capacity. [what-when-how.com] […] red blood cell mass; Increased hematocrit; Increased hemoglobin; Normal oxygen affinity of hemoglobin; Hypersensitivity of erythroid colony-forming units to erythropoietin [genome.jp] Hemoconcentration Hemoglobin concentration and hematocrit increased reaching 16.4 ± 0.9 g/dL and 48.8% ± 1.6%, respectively, at 100 W and were maintained until recovery. [liebertpub.com] There may be an elevation of the hemoglobin and hematocrit indicating hemoconcentration. [diki.pl] Hemoconcentration, characterized by increased hematocrit (Hct) and hemoglobin (Hgb) levels, describes the decrease in the ratio between plasma volume and the cellular components [oatext.com] Carboxyhemoglobinemia A similar increase in hematocrit can be achieved with erythropoietin injections, which can increase maximal exercise capacity. [what-when-how.com] In erythrocythemia, DLco is increased because hematocrit is increased and because of the vascular recruitment that occurs with increased pulmonary pressures due to increased [merckmanuals.com] Over several days, serum erythropoietin levels return to normal, but the increase in hematocrit is sustained. [what-when-how.com] Eisenmenger Syndrome […] in red blood cell mass, defined in neonates as a venous hematocrit ≥ 65%; this increase can lead to hyperviscosity with sludging of blood within vessels... read more, hyperviscosity [msdmanuals.com] With shunt reversal, patients become cyanotic and gradually there is a compensatory increase in hematocrit (erythrocytosis). [radiopaedia.org] Laboratory testing shows polycythemia with hematocrit > 55%. [msdmanuals.com] Cyanotic Congenital Heart Disease However, at highly increased hematocrit levels patients may experience hyperviscosity symptoms. [ncbi.nlm.nih.gov] Mean systemic arterial oxygen saturation was 77% (range 71-81%) and mean hematocrit was 64.5% (range 53.7-69.5%). [ncbi.nlm.nih.gov] In addition, high hematocrit increases the risk of cerebro-vascular accidents. Polycythemia should be treated by erythropheresis instead of instead of phlebotomy. [omicsonline.org] Polycythemia Type Chuvash Even modest increases in the hemoglobin/hematocrit level can have a major impact on whole blood viscosity. [mhmedical.com] A similar increase in hematocrit can be achieved with erythropoietin injections, which can increase maximal exercise capacity. [what-when-how.com] Oxygen was then increased to 2 L/min. After 2 months hematocrit was reduced to 51% and hemoglobin was reduced to 17 g/dL. [mrmjournal.biomedcentral.com] Myeloproliferative Disease Erythroid-specific expression of heterozygous or homozygous Jak2V617F resulted in a polycythemia-like phenotype characterized by increase in hematocrit and hemoglobin, increased [ncbi.nlm.nih.gov] […] incidence of peptic ulcer disease The CBC of a person with PV looks like: Increased Hg: 12-28 Increased Hematocrit: >60% Elevated platelets WBC normal What are potential [quizlet.com] Exclusion Criteria: Subjects who have a known acquired cause of polycythemia (increased hemoglobin/hematocrit), such as people living in high altitudes (in excess of 14,000 [clinicaltrials.gov] Thrombocytosis […] in hematocrit and an increase in the JAK2V617F allele burden. [merckmanuals.com] As thrombocyte count increases, so decreases the hematocrit and hemaglobin concentration and erythrocyte count. [dspace.lu.lv] An increase in hematocrit or leukocyte count suggests myeloproliferative neoplasms, whereas presence of macrocytosis or leukoerythroblastic blood smear, or abnormal platelet [ascopost.com] Sleep Apnea In this study, although hematocrit levels were not increased in patients with OSAS, hematocrit was positively correlated with AHI, the severity of index of OSAS. [omicsonline.org] […] blood pressure variability, diabetes and insulin resistance Hematologic and biochemical findings Elevated hematocrit Hyperuricemia Reduced renin levels during sleep Increased [aafp.org] Choi JB, Loredo JS, Norman D, Mills PJ, Ancoli-Israel S, Ziegler MG, Dimsdale JE (2006) Does obstructive sleep apnea increase hematocrit? [link.springer.com] Dehydration In patients with unprovoked VTE (n = 269), levels of BUN and hematocrit were significantly increased in the peak incidence group compared to lowest incidence group (19.5 ± [ncbi.nlm.nih.gov] Blood serum studies reveal increased sodium, protein, hematocrit, and serum osmolality. [medical-dictionary.thefreedictionary.com] Urinary findings include a decrease in urine volume (oliguria), specific gravity higher than 1.030, and an increase in urine osmolality. [medical-dictionary.thefreedictionary.com] Uterine Leiomyoma Overall, serum levels of hemoglobin, hematocrit and ferritin increased among LNG-IUD users in studies that assessed these outcomes. [ncbi.nlm.nih.gov] Her hematocrit was 19%, and total white cell count was 6.0 × 10 9 /L. The neutrophils were increased. [archms.org] Ovarian Hyperstimulation Syndrome Hematologic findings include increased hematocrit (secondary to increased capillary permeability and fluid loss) and elevated white blood cell count, a multifactorial finding [asja.eg.net] Any increase in the hematocrit as it approaches 45% does not accurately reflect the magnitude of plasma volume depletion and thus the seriousness of the patient’s condition [ivf-worldwide.com] > 45%), thrombosis, and disseminated intravascular coagulation from the increased viscosity of the blood. [mdedge.com] Recurrent Pulmonary Embolism Suggested Baseline Laboratory Studies for Patients with Venous Thromboembolism Test Finding Associated condition Complete blood count Increased hematocrit or platelet count [aafp.org] Accidental Hypothermia • CBC: Hematocrit increases as the plasma volume decreases. [ahcmedia.com] For each 1°C drop in core temperature, the hematocrit increases approximately 2%. • Serum electrolytes: Hypokalemia or hyperkalemia may occur and should be monitored closely [ahcmedia.com] Renal Cell Carcinoma On admission, he was found to have increased hemoglobin and hematocrit. [ncbi.nlm.nih.gov] His hemoglobin and hematocrit remained elevated throughout his hospital course, and his erythropoietin level was found to be elevated as well. [ncbi.nlm.nih.gov] CONCLUSIONS High blood viscosity is associated with increased incidence of cardiovascular complications, including reduced cerebral blood flow. [ncbi.nlm.nih.gov] Ayerza Syndrome Erythrocytosis refers to an increase in the concentration of erythrocytes, however, whether measured as number of cells, hemoglobin, or packed cell volume (hematocrit). [enotes.tripod.com] Satisfactory control of hematocrit can be obtained in at least two-thirds of patients by reduction of excess weight, improved hypertension control, avoidance of diuretics, [enotes.tripod.com] As noted previously, phlebotomy increases cerebral blood flow even in patients with relative polycythemia; whether it is of symptomatic benefit is less clear. [enotes.tripod.com] Gestational Diabetes hematocrit. [emedicine.medscape.com] […] accompanied by surges in adrenal catecholamines, which, in turn, cause hypertension, cardiac remodeling and hypertrophy, stimulation of erythropoietin, red cell hyperplasia, and increased [emedicine.medscape.com] Pyruvate Kinase Deficiency […] density of mature erythrocytes, increased hematocrit, as well as decreased iron overload in kidney and liver and decreased serum iron. [ncbi.nlm.nih.gov] Thus, for a comparative hemoglobin and Hematocrit level, an individual with PKD has an enhanced exercise capacity and fewer symptoms. [namrata.co] Hematocrit W.&C.. Neutrophils. [kundoc.com] Pickwickian Syndrome This results in polycythemia, abnormally increased numbers of circulating red blood cells and an elevated hematocrit. [en.wikipedia.org] […] leads to accumulation of fluid in the skin (edema), and in more severe cases the liver and the abdominal cavity.The chronically low oxygen levels in the blood also lead to increased [en.wikipedia.org] Pheochromocytoma Her polycythemia symptoms and hematocrit levels continued to worsen from 2007 to 2011, with an increased frequency of phlebotomies. [ncbi.nlm.nih.gov] Postoperatively, until early 2013, her hematocrit levels remained normalized. Following this, the hematocrit levels ranged between 46.4 and 48.9% [35-45%]. [ncbi.nlm.nih.gov] POEMS Syndrome Lab investigations revealed hemoglobin of 16.7 g/dl, hematocrit 49%, platelet counts of 560,000/ul. [austinpublishinggroup.com] Bone marrow aspiration and trephine biopsy showed 6% plasma cells which were CD38 and CD138 positive with increased megakaryocytes. PCR for JAK-2 mutation was negative. [austinpublishinggroup.com] Transposition of the Great Vessels Hematocrit can be assessed at this time and corrected if it falls below acceptable levels (25% to 30%). [tele.med.ru] Respiratory acidosis is corrected by increasing the gas sweep through the oxygenator, and metabolic acidosis is corrected with sodium bicarbonate. [tele.med.ru] Acute Mountain Sickness However, increases in erythrocyte count, hematocrit and hemoglobin associated with EPO therapy have been shown to decrease fatigue and increase work capacity and exercise [clinicaltrials.gov] Cardiac output increases through an increase in heart rate. [13] The body's response to high altitude includes the following: [13] ↑ Erythropoietin → ↑ hematocrit and hemoglobin [en.wikipedia.org] Institute of Environmental Medicine (USARIEM) reported that autologous erythrocyte infusion did not ameliorate the decrement in maximal oxygen uptake at 4,300m altitude despite increasing [clinicaltrials.gov]
