Create issue ticket

434 Possible Causes for Hematuria, Leukocytosis, Splenomegaly

  • Primary Myelofibrosis

    We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[ncbi.nlm.nih.gov] Leukocytosis is occasionally seen in patients with presumptive but undiagnosed myeloproliferative disorders (MPD).[ncbi.nlm.nih.gov] The condition may result in GI tract hemorrhage, spinal cord compression, focal seizures, symptoms related to brain tumors, ascites, hematuria, pericardial effusion, pleural[emedicine.medscape.com]

  • Infective Endocarditis

    Blood or blood cells may be present in the urine (hematuria). Small red or purple spots composed of blood (petechiae) may cover the skin of the upper trunk.[rarediseases.org] This score includes clinical, epidemiological (male, fever, splenomegaly, clubbing, vascular disease and stroke) and biological criteria (Leucocytes 10,000/mm3, sedimentation[ncbi.nlm.nih.gov] CASE PRESENTATION: A 57-year-old white man presented with bilateral large leg ulcers, fever, and marked leukocytosis.[ncbi.nlm.nih.gov]

  • Leukemia

    Five features were present in 50% of children: hepatomegaly (64%), splenomegaly (61%), pallor (54%), fever (53%) and bruising (52%).[ncbi.nlm.nih.gov] Evaluation Step 0: Leukocytosis ( White Blood Cell Count 11,000/mm3) Confirmed with a second Complete Blood Count with differential No other obvious cause for Leukocytosis[fpnotebook.com] On the seventh day after the completion of chemotherapy, the patient was diagnosed with rhabdomyolysis because he complained of perianal pain and hematuria, and his creatine[ncbi.nlm.nih.gov]

  • Myeloproliferative Disease

    CML: demonstrates increased production of neutrophils and marked splenomegaly.[ncbi.nlm.nih.gov] […] a Philadelphia (Ph) chromosome without DNA breakpoints in the M-bcr region; (3) the spontaneous loss of detectable Ph-positive cells, 5 years after the first finding of leukocytosis[ncbi.nlm.nih.gov] Leukocytosis is also found in patients with essential thrombocythemia (primary thrombocythemia).[medindia.net]

  • Acute Myelocytic Leukemia

    Typical symptoms are spongy and bleeding gums, anemia, fatigue, fever, dyspnea, moderate splenomegaly, joint and bone pain, and repeated infections.[medical-dictionary.thefreedictionary.com] Thus, the bone marrow and peripheral blood are characterized by leukocytosis with a predominance of immature cells, primarily blasts.[ncbi.nlm.nih.gov] Patients may claim a propensity for epistaxis, bleeding gums, melena and hematochezia, and hematuria.[symptoma.com]

  • Bacterial Endocarditis

    Also, urinalysis typically shows microscopic hematuria and may also depict red blood cell (RBC) casts.[symptoma.com] The condition is characterized by heart murmur, prolonged fever, bacteremia, splenomegaly, and embolic phenomena.[medical-dictionary.thefreedictionary.com] Microscopic hematuria is seen in about 50% of cases. Gross hematuria indicates the presence of focal or diffuse glomerulonephritis or possible embolic renal infarction.[antimicrobe.org]

  • Sickle Cell Disease

    These findings are illustrated with a case of a 9-year old girl with sickle cell disease who was referred with painless gross hematuria.[ncbi.nlm.nih.gov] In two mouse SCD models, Berkeley and SAD, inhibition of red blood cell dehydration and sickling was achieved with correction of hematological parameters, splenomegaly, and[ncbi.nlm.nih.gov] Leukocytosis or erythema does not accompany the swelling.[emedicine.medscape.com]

  • Familial Myelofibrosis

    Amelioration of splenomegaly and anaemia was also observed in mice treated with Elo and Rom than Rom alone.[jshem.or.jp]

  • Acute Myeloid Leukemia with Myelodysplasia-related Changes

    We retrospectively analyzed 449 patients with AML under the WHO classification of AML 2008 and probed implications of this classification in diagnosis and treatment of acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) among them. The clinical presentations, biological features, treatments, and[…][ncbi.nlm.nih.gov]

  • Essential Thrombocythemia

    […] essential thrombocythemia (ET) are myeloproliferative neoplasms respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly[ncbi.nlm.nih.gov] In addition, leukocytosis has been identified as an important prognostic marker in otherwise WHO-defined ET.[ncbi.nlm.nih.gov] We present the case of a 41-year-old woman with thrombocytosis and mild splenomegaly. Clinical suspicion was of chronic myeloproliferative neoplasia (CMN).[ncbi.nlm.nih.gov]

Similar symptoms