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510 Possible Causes for Hematuria, Pallor, Splenomegaly

  • Infective Endocarditis

    Blood or blood cells may be present in the urine (hematuria). Small red or purple spots composed of blood (petechiae) may cover the skin of the upper trunk.[rarediseases.org] This score includes clinical, epidemiological (male, fever, splenomegaly, clubbing, vascular disease and stroke) and biological criteria (Leucocytes 10,000/mm3, sedimentation[ncbi.nlm.nih.gov] Additional findings may include splenomegaly, gallop or arrhythmia, pericardial or pleural rubs, rales, pallor, acute septic monoarticular arthritis or delirium.[symptoma.com]

  • Primary Myelofibrosis

    The condition may result in GI tract hemorrhage, spinal cord compression, focal seizures, symptoms related to brain tumors, ascites, hematuria, pericardial effusion, pleural[emedicine.medscape.com] We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[ncbi.nlm.nih.gov] Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy[orpha.net]

  • Leukemia

    On the seventh day after the completion of chemotherapy, the patient was diagnosed with rhabdomyolysis because he complained of perianal pain and hematuria, and his creatine[ncbi.nlm.nih.gov] Five features were present in 50% of children: hepatomegaly (64%), splenomegaly (61%), pallor (54%), fever (53%) and bruising (52%).[ncbi.nlm.nih.gov] […] leukemia (T-PLL) is the most common type of mature T-cell leukemia and is characterized by a rapidly rising peripheral blood lymphocyte count, bone marrow involvement, and splenomegaly[web.archive.org]

  • Nephroblastoma

    The mass may be discovered incidentally or during a workup following trauma, hematuria, or hypertension.[symptoma.com] It is also important to investigate “B” symptoms associated with any lymphadenopathy or splenomegaly. Laboratory tests can often be helpful in ambiguous cases.[aafp.org] Non-specific symptoms are present in less than 1/3 children: subfebrility, weakness, pallor, loss of appetite constipation, abdominal pain 10–30 % patients develop micro or[telemedicina.med.muni.cz]

  • Myelodysplasia

    Therapy with granulocyte-colony stimulating factor (G-CSF) and granulocyte-monocyte-colony stimulating factor (GM-CSF) caused splenomegaly and severe thrombocytopenia, which[ncbi.nlm.nih.gov] Some patients may develop hemoptysis, hematuria or have blood in stools. Severe cases of anemia may manifest as tachycardia and congestive heart failure.[symptoma.com] Symptoms are referable to the specific cell line most affected and may include fatigue, weakness, pallor (secondary to anemia), increased infections and fever (secondary to[msdmanuals.com]

  • Bacterial Endocarditis

    The condition is characterized by heart murmur, prolonged fever, bacteremia, splenomegaly, and embolic phenomena.[medical-dictionary.thefreedictionary.com] Also, urinalysis typically shows microscopic hematuria and may also depict red blood cell (RBC) casts.[symptoma.com] Physical examination may be normal or include pallor, fever, change in a preexisting murmur or development of a new regurgitant murmur, and tachycardia.[merckmanuals.com]

  • Systemic Lupus Erythematosus

    […] relapsing illness, with a variety of different presentations. [ 5 , 6 ] Symptoms and signs are often nonspecific - eg, fatigue (can be severe and debilitating), malaise, fever, splenomegaly[patient.info] At present, the level of complement restored to normal, hematuria and proteinuria disappeared, and liver function returned to normal.[ncbi.nlm.nih.gov] Fever, arthralgia and pallor are the most frequent clinical manifestations among the children.[ncbi.nlm.nih.gov]

  • Acute Myelocytic Leukemia

    Patients may claim a propensity for epistaxis, bleeding gums, melena and hematochezia, and hematuria.[symptoma.com] Typical symptoms are spongy and bleeding gums, anemia, fatigue, fever, dyspnea, moderate splenomegaly, joint and bone pain, and repeated infections.[medical-dictionary.thefreedictionary.com] The main clinical picture consists of a short time period with pallor, fatigue, fever, infections and hemorrhages. Presence of all these features is not compulsory.[orpha.net]

  • Myeloproliferative Disease

    CML: demonstrates increased production of neutrophils and marked splenomegaly.[ncbi.nlm.nih.gov] […] stupor from leukostasis Left upper quadrant and left shoulder pain as a consequence of splenic infarction and perisplenitis Clinical symptoms can include the following: Pallor[emedicine.com] The unusual case of myeloproliferative disease described here is characterized by the following features: (1) a clinically completely silent course for 11 years without splenomegaly[ncbi.nlm.nih.gov]

  • B-Precursor Acute Lymphoblastic Leukemia

    […] are also nonspecific and may include any of the following: Pallor, fatigue and weakness, caused by anemia Recurring infections due to leukocytopenia Petechiae, epistaxis, hematuria[symptoma.com] 64.0%) 66 (66%) 62 (%) 0.556 Bleeding 96 (48.0%) 45 (45%) 51 (51%) 0.396 Lymphadenopathy 112 (56.0%) 53 (53%) 59 (59%) 0.393 Hepatomegaly 84 (42.0%) 46 (46%) 38 (38%) 0.252 Splenomegaly[omicsonline.org] Lymphadenopathy, hepatomegaly, splenomegaly, arthralgia and bone pain are signs and symptoms also reported (1, 3, 6).[jbpml.org.br]

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