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54 Possible Causes for Hemochromatosis, Red Blood Cell Distribution Width Increased

  • Iron Deficiency Anemia

    […] high red blood cell distribution width, reflecting an increased variability in the size of red blood cells.A low mean corpuscular volume also appears during the course of[en.wikipedia.org] In extreme cases too much iron can lead to hemochromatosis, which can be deadly 3 . The best and safest way to keep an eye on your iron is to get a blood test.[trainingpeaks.com] It could also cause an iron overload condition called hemochromatosis , especially in people who have a genetic tendency toward storing too much iron in their bodies.[cham.org]

  • Thalassemia

    blood cell distribution width High Normal; occasionally high Normal Ferritin Low Normal Normal Mentzer index for children (MCV/red blood cell count) 13 13 13 Hb electrophoresis[aafp.org] Abstract The authors present a unique case of torsades de pointes in a β-thalassemia patient with early iron overload in the absence of any structural abnormalities as seen in hemochromatosis[ncbi.nlm.nih.gov] […] cut appearance of the skull secondary to extramedullary hematopoiesis in the skull Treatment β-thalassemia major frequent transfusions required can cause iron overload and hemochromatosis[medbullets.com]

  • Chronic Liver Disease

    One involves hemochromatosis.[gastroenterologyandhepatology.net] I was told I actually don't have hemochromatosis but I’m a cirrhotic NASH ( non-alcoholic steatohepatitis ) patient.[scopeblog.stanford.edu] Other less common disorders include Primary Biliary Cirrhosis, Fatty Liver Syndrome, Hemochromatosis and Sclerosing Cholangitis.[web.archive.org]

  • Iron Deficiency

    Average size of RBCs (MCV) — may be decreased Average amount of Hb in RBCs (MCH) — may be decreased Increased variation in the size of RBCs (red cell distribution width (RDW[labtestsonline.org.au] Hemochromatosis is the disease resulting from significant iron overload. Hemochromatosis can have genetic and non-genetic causes.[web.archive.org] This is reflected in the red blood cell distribution width (RDW); thus, the earliest evidence of the development of an iron-deficient erythropoiesis is seen in the peripheral[emedicine.com]

  • Sideroblastic Anemia

    Red cell distribution width is increased. White blood cells and platelets are normal.[encyclopedia.com] Abstract A severely anemic 3-year-old girl with refractory sideroblastic anemia and fulminant, fatal hemochromatosis is described.[ncbi.nlm.nih.gov] Thus, ALAS2 mutations might contribute to more severe iron loading in persons with primary hemochromatosis.[ncbi.nlm.nih.gov]

  • Heart Failure

    blood cell distribution width II - Prognostic implications Many studies have shown anaemia to increase mortality and morbidity in HF patients ( 1 , 5 , 8 , 9 ) and to cause[web.archive.org] Abstract BACKGROUND: Juvenile hemochromatosis is the most severe form of iron overloading phenotype.[ncbi.nlm.nih.gov] CMP in storage diseases ( amyloidosis , hemochromatosis ) Symptomatic therapy and treatment of the underlying disease, eg. chemotherapy in plasmocytoma , venesection in hemochromatosis[flexikon.doccheck.com]

  • Sickle Cell Thalassemia Disease

    But having too much iron, called hemochromatosis – or – iron overload is also a problem, creating poisonous conditions for the liver, heart and pancreas.[hbhm.tv] See also hemochromatosis , hemosiderosis .[medical-dictionary.thefreedictionary.com]

  • Myelodysplasia

    Barnes, MD Hemochromatosis Anthony S. Tavill, MD Hepatic Encephalopathy Mina Shaker, MD; William D.[clevelandclinicmeded.com] Judit Várkonyi, Miklós Molnár, Margit Kovács and Zoltán Prohászka , Iron Overload in Gaucher Cells and Bone Marrow that Is Not Associated with Hemochromatosis Gene Mutations[doi.org] […] specific therapies patients receive may alleviate the RBC transfusion need in some cases, many MDS patients may not respond to these treatments and thus may develop secondary hemochromatosis[en.wikipedia.org]

  • Folate-Deficiency Anemia

    […] kidney failure, anemia of chronic disease, or polycythemia vera. 3 Ferritin Measurement of ferritin aids in the diagnosis of diseases affecting iron metabolism, such as hemochromatosis[healthcare.siemens.com]

  • Sickle Cell Disease

    Kell , Profound Morphological Changes in the Erythrocytes and Fibrin Networks of Patients with Hemochromatosis or with Hyperferritinemia, and Their Normalization by Iron Chelators[dx.doi.org] Iron overload (transfusional hemochromatosis) occurs because the body has no mechanism to increase the "excretion" of the large amount of added iron provided by the transfused[clinicaladvisor.com]

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