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235 Possible Causes for Hemoglobin Decreased, Hypercellular Bone Marrow

  • Leukemia

    The number of red blood cells on a blood count (and the hemoglobin) will be below normal.[childrensnational.org] Bone marrow aspirate showed hypercellularity with increased myelopoiesis and markedly suppressed megakaryopoiesis giving an impression of acute myeloid leukemia and was confirmed[ncbi.nlm.nih.gov] Another important feature of bone marrow samples is its cellularity. Normal bone marrow contains hematopoietic (blood-forming) cells and fat cells.[web.archive.org]

  • Hereditary Spherocytosis

    All experienced an increase in hemoglobin and decrease in reticulocyte count early after LPS and at last follow-up. Twenty-two were sent for genetic analysis.[ncbi.nlm.nih.gov] Post-splenectomy blood changes include an increased hemoglobin level, decreased reticulocyte count, and the appearance of specific inclusion bodies and target cells.[steadyhealth.com] However, his hemoglobin gradually decreased (less than 7 g/dl) after leaving our hospital, and erythrocyte transfusion was needed.[jhoonline.biomedcentral.com]

  • Pernicious Anemia

    LDH levels decrease and hemoglobin levels increase by about 1 g/dL/wk. A rise in LDH might indicate a relapse.[emedicine.medscape.com] Failure to consume enough iron can disrupt hemoglobin production, leading to the presence fewer active heme groups in the bloodstream, a subsequent decrease in oxygen transport[livestrong.com] KEY TERMS Anemia — A condition in which those elements of the blood responsible for oxygen delivery throughout the body (red blood cells, hemoglobin) are decreased in quantity[encyclopedia.com]

  • Paroxysmal Nocturnal Hemoglobinuria

    Blood complete picture showed decreased hemoglobin and reticulocytosis upto 30%.[ncbi.nlm.nih.gov] These patients tend to have a normocellular to hypercellular bone marrow with erythroid hyperplasia, an elevated reticulocyte count, a large population of PNH cells (usually[bloodjournal.org] Together, these results argue that the decline in hemoglobin A1c was due to decreased RBC survival secondary to PNH.[ncbi.nlm.nih.gov]

  • Chronic Myeloid Leukemia

    hemoglobin (decrease in blood cells which carry oxygen) Hemorrhage (abnormal bleeding) Nausea Fatigue Rash If you are experiencing any of the above-mentioned side effects[us.gleevec.com] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] Because of such abnormal shapes, these cells are destroyed before releasing into the peripheral blood circulation, leading to cytopenias and hypercellular bone marrow.[lecturio.com]

  • Autoimmune Hemolytic Anemia

    Laboratory data revealed progressive decrease in hemoglobin during her hospitalization due to pulmonary infection in 2016.[ncbi.nlm.nih.gov] Subsequently, the patient underwent a bone marrow biopsy that showed a hypercellular marrow with erythroid hyperplasia, but no evidence of dysplasia or lymphoma.[jmedicalcasereports.com] He presented with a markedly elevated C-reactive protein (CRP; 46 mg/L [normal, 0-5 mg/L]) before onset of a decrease in hemoglobin.[ncbi.nlm.nih.gov]

  • Chronic Phase of Chronic Myeloid Leukemia

    hemoglobin (decrease in blood cells which carry oxygen) Hemorrhage (abnormal bleeding) Nausea Fatigue Rash If you are experiencing any of the above-mentioned side effects[gleevec.com] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] A bone marrow biopsy and aspiration demonstrated a hypercellular marrow with no other significant morphologic abnormalities.[hematologyandoncology.net]

  • Cooley's Anemia

    Cooley's anemia disease causes a dramatic decrease in the production of hemoglobin, resulting in anemia. This anemia can cause people to be more tired than normal.[dshs.state.tx.us] Average size of RBCs (mean corpuscular volume, MCV)—decreased Average amount of hemoglobin in RBCs (mean corpuscular hemoglobin, MCH)—decreased Hemoglobin concentration (mean[labtestsonline.org] However, hemoglobin (Hb) levels often decrease over time, splenomegaly appears, and progressive iron overload occurs from increased gastrointestinal iron absorption.[news.weill.cornell.edu]

  • Sickle Cell Disease

    Mean decrease in sickle hemoglobin levels was higher in automated-red blood cell exchange (p 0.001) and permitted a higher sickle hemoglobin level decrease per volume removed[ncbi.nlm.nih.gov] By inhibiting sickling, increased levels of fetal hemoglobin might decrease the frequency of painful crises.[ncbi.nlm.nih.gov] Hemoglobin F predominates during gestation and gradually decreases, particularly in the first months of life; its concentration increases in certain disorders of hemoglobin[msdmanuals.com]

  • Acute Leukemia

    ALL : Hypercellular bone marrow Numerous tightly packed lymphoblasts with undetectable cytoplasm, round, irregular, cleaved nuclei, dispersed chromatin, small nucleoli B[pathologyoutlines.com] Bone marrow aspirate examination revealed hypercellularity with 70% blast cells.[ncbi.nlm.nih.gov] Bone marrow aspiration demonstrated hypercellular marrow (nucleated cell count 1.84 104/μL) and 89.0% of blast-like cells of all nucleated cells.[ncbi.nlm.nih.gov]

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