Create issue ticket

61 Possible Causes for Hemoglobin Electrophoresis Abnormal, Hypersplenism, Mild Anemia

  • Thalassemia

    Thalassemia is usually diagnosed through the use of blood tests showing small abnormally shaped red blood cells and/or a hemoglobin electrophoresis showing abnormal hemoglobin[] Mild anemia can make you feel tired. Mild anemia caused by alpha thalassemia trait might be mistaken for iron-deficiency anemia.[] Hypersplenism, cholelithiasis, extramedullary hematopoiesis, thrombotic complications and progressive iron overload are the main clinical features that may complicate the[]

  • Haemoglobin E Disease

    Hemoglobin S and hemoglobin C are the most common types of abnormal hemoglobin that may be found by an electrophoresis test.[] Homozygotes display mild hemolytic anemia and splenomegaly (enlarged spleen). The HbCSpr trait is asymptomatic.[] Extramedullary hematopoiesis and hemolysis causes splenomegaly, which produces hypersplenism, and more hemolysis.[]

  • Alpha-Thalassemia

    […] in Alkaline Electrophoresis Normal Hemoglobin Electrophoresis Sample Alkaline Hemoglobin Electrophoresis Densitometer Tracings In what order do normal and abnormal hemoglobins[] The heterozygous form may be asymptomatic or marked by mild anemia. β-thalassemia ( beta-thalassemia ) that caused by diminished synthesis of beta chains of hemoglobin.[] Hypersplenism and gallstones are also found, as well as acute episodes of hemolysis in response to oxidant drugs and infections.[]

  • Congenital Heinz Body Hemolytic Anemia

    For more information see HAEVP / Hemolytic Anemia Evaluation; or HBELC / Hemoglobin Electrophoresis Cascade, Blood; or THEVP / Thalassemia and Hemoglobinopathy Evaluation;[] Resolves with aging as adult hemoglobin replaces fetal hemoglobin Other presentations Congenital anemia, splenomegaly, pigmented gallstones Mild or minimal anemia with reticulocytosis[] Nonimmune Causes Microangiopathic Hemolytic Anemia Hypersplenism Toxic Causes Drugs (e.g., vitamin K, phenacetin, sulfones, benzenes, phenylhydralazine) Lead Venoms Infectious[]

  • Hemoglobinopathy

    It is estimated that approximately 2 percent of African-Americans possess one gene for C hemoglobin. This is usually demonstrated on hemoglobin electrophoresis.[] A 52-year-old African-American man had a mild anemia (hemoglobin of 103 g/L) and target cells on the peripheral blood smear as shown.[] Also, Splenectomy reduces transfusion requirements in the first year after surgery in patients with thalassemia major and hypersplenism [ 30 ].[]

  • Hemoglobin E-Thalassemia

    Usually the diagnosis is confirmed by a blood test called a hemoglobin electrophoresis and/or a DNA test for abnormal hemoglobin genes.[] Homozygous HbE is common in Southeast Asia and presents with very mild anemia, seldom requiring transfusion.[] Splenomegaly may be associated with an overactive spleen (hypersplenism), a condition that can develops because too many blood cells build up and are destroyed within the[]

  • Hemolytic Anemia

    Cation exchange HPLC, capillary electrophoresis, and hemoglobin stability studies will always be performed.[] All the children presented with neonatal hemolytic anemia. Beyond the neonatal period, they did not have jaundice or hemolysis, but continued to have mild anemia.[] The condition is termed, somewhat vaguely, hypersplenism.[]

  • Beta Thalassemia

    A small sample of blood is checked under a microscope to see if they look abnormal. Hemoglobin electrophoresis. This test measures the types and amount of hemoglobin.[] The heterozygous form may be asymptomatic or marked by mild anemia. β-thalassemia ( beta-thalassemia ) that caused by diminished synthesis of beta chains of hemoglobin.[] Anaesthetic management of beta thalassemia major with hypersplenism for splenectomy in pediatric age group: Report of four cases.[]

  • Anemia

    Hemoglobin electrophoresis : This identifies any abnormal types of hemoglobin and helps diagnose sickle cell disease, thalassemia, and other inherited forms of anemia.[] There are many types and causes of anemia. Mild anemia is a common and treatable condition that can occur in anyone.[] […] etiologies of hemolysis include: Autoimmune hemolytic anemias Drug, or toxin induced hemolysis Sepsis and burns with multifactorial shortening of RBC survival Cirrhosis, and hypersplenism[]

  • Normocytic Normochromic Anemia

    Electrophoresis will confirm the diagnosis, depending upon the precise hemoglobin variant discovered. (See Table 4.)[] The mild anemias associated with deficiencies of anterior pituitary, thyroid, adrenocortical, or testicular hormones usually are normocytic.[] […] committed erythroid stem cell. 12 Other causes of Normocytic Normochromic Anemia Myelopthesic anemia – replacement of bone marrow by fibrotic, granulomatous, or neoplastic cells Hypersplenism[]

Similar symptoms