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76 Possible Causes for Hemoglobin Electrophoresis Abnormal, Jaundice, Mild Anemia

  • Thalassemia

    Diagnostic methods Diagnosis is suspected in infants younger than 2 years of age with severe microcytic anemia, mild jaundice and hepatosplenomegaly.[orpha.net] Thalassemia is usually diagnosed through the use of blood tests showing small abnormally shaped red blood cells and/or a hemoglobin electrophoresis showing abnormal hemoglobin[helpthals.org] Mild anemia can make you feel tired. Mild anemia caused by alpha thalassemia trait might be mistaken for iron-deficiency anemia.[web.archive.org]

  • Alpha-Thalassemia

    Alpha-thalassemia Alpha-thalassemia inheritance pattern Specialty Hematology Symptoms Jaundice, Fatigue Anie KA, Massaglia P (March 2014).[en.wikipedia.org] […] in Alkaline Electrophoresis Normal Hemoglobin Electrophoresis Sample Alkaline Hemoglobin Electrophoresis Densitometer Tracings In what order do normal and abnormal hemoglobins[medialabinc.net] The heterozygous form may be asymptomatic or marked by mild anemia. β-thalassemia ( beta-thalassemia ) that caused by diminished synthesis of beta chains of hemoglobin.[medical-dictionary.thefreedictionary.com]

  • Haemoglobin E Disease

    While evaluating the patients of jaundice, we came across two cases of hemoglobin E (Hb E) disorders.[ijpmonline.org] Hemoglobin S and hemoglobin C are the most common types of abnormal hemoglobin that may be found by an electrophoresis test.[northshore.org] Homozygotes display mild hemolytic anemia and splenomegaly (enlarged spleen). The HbCSpr trait is asymptomatic.[wikilectures.eu]

  • Hemoglobin C Disease

    In some cases, jaundice may occur. Some people may develop gallstones that need to be treated. In most cases, no treatment is needed.[nlm.nih.gov] Laboratory studies The following laboratory studies should be done when Hemoglobin C disease is suspected: Hemoglobin electrophoresis: To further evaluate the abnormality,[symptoma.com] There may be intermittent abdominal discomfort, splenomegaly, and slight jaundice.[connects.catalyst.harvard.edu]

  • Hemoglobin D Disease

    Two of 3 patients had fever, joint pains and jaundice. One of the patients had hepatosplenomegaly. Total hemoglobin ranged from 7.1 to 8.4 gm/dl.[nepjol.info] A hemoglobin electrophoresis will indicate if there are any abnormal types of hemoglobin caused by genetic disorders.[healthline.com] This disease causes mild anemia but none of the other symptoms that occur in sickle cell disease and hemoglobin C disease.[merckmanuals.com]

  • Hemoglobin E-Thalassemia

    Patients come to the hospital because of anemia, fever, abdominal mass, and jaundice.[journals.lww.com] Usually the diagnosis is confirmed by a blood test called a hemoglobin electrophoresis and/or a DNA test for abnormal hemoglobin genes.[kidshealth.org] Homozygous HbE is common in Southeast Asia and presents with very mild anemia, seldom requiring transfusion.[labce.com]

  • Hemoglobinopathy

    […] describe the first successful bone marrow transplant for the treatment of hemoglobinopathy Olmsted in a boy who presented with severe transfusion-dependent hemolytic anemia and jaundice[ncbi.nlm.nih.gov] It is estimated that approximately 2 percent of African-Americans possess one gene for C hemoglobin. This is usually demonstrated on hemoglobin electrophoresis.[ncbi.nlm.nih.gov] A 52-year-old African-American man had a mild anemia (hemoglobin of 103 g/L) and target cells on the peripheral blood smear as shown.[bloodjournal.org]

  • Congenital Heinz Body Hemolytic Anemia

    The first patient was a full-term infant who developed jaundice and symptoms attributable to anemia at 2 weeks of life.[pediatrics.aappublications.org] For more information see HAEVP / Hemolytic Anemia Evaluation; or HBELC / Hemoglobin Electrophoresis Cascade, Blood; or THEVP / Thalassemia and Hemoglobinopathy Evaluation;[mayomedicallaboratories.com] Resolves with aging as adult hemoglobin replaces fetal hemoglobin Other presentations Congenital anemia, splenomegaly, pigmented gallstones Mild or minimal anemia with reticulocytosis[arupconsult.com]

  • Sickle Cell Disease

    Jaundice, or yellowing of the skin, eyes, and mouth. Jaundice is a common sign and symptom of sickle disease.[hopkinsmedicine.org] A blood test called hemoglobin electrophoresis confirms the diagnosis, by identifying the abnormal form of hemoglobin that is produced in people with the disease.[drugs.com] Partial exchange transfusion should be reserved for children with only mild anemia (Hb 9 g/dL) but deteriorating respiratory status.[ncbi.nlm.nih.gov]

  • Hemoglobin SC Disease

    We present a case of fulminant ASSC in an adult with hemoglobin SC who developed high fever, intense abdominal pain, leukocytosis, and jaundice.[ncbi.nlm.nih.gov] However, in such cases, acid electrophoresis demonstrates no abnormal hemoglobin in the HbC position.[path.upmc.edu] Too much hemoglobin C can reduce the number and size of red blood cells in your body, causing mild anemia.[stjude.org]

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