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62 Possible Causes for Hemoglobin Electrophoresis Abnormal, Mild Anemia, Pulmonary Hypertension

  • Thalassemia

    Thalassemia is usually diagnosed through the use of blood tests showing small abnormally shaped red blood cells and/or a hemoglobin electrophoresis showing abnormal hemoglobin[helpthals.org] Mild anemia can make you feel tired. Mild anemia caused by alpha thalassemia trait might be mistaken for iron-deficiency anemia.[web.archive.org] The latter are linked to a high prevalence of thromboembolic and cerebrovascular events, as well as leg ulcers and pulmonary hypertension.[ncbi.nlm.nih.gov]

  • Sickle Cell Disease

    A blood test called hemoglobin electrophoresis confirms the diagnosis, by identifying the abnormal form of hemoglobin that is produced in people with the disease.[drugs.com] Partial exchange transfusion should be reserved for children with only mild anemia (Hb 9 g/dL) but deteriorating respiratory status.[ncbi.nlm.nih.gov] Steady-state mild pulmonary hypertension is a risk factor for death in adults with sickle cell disease.[ncbi.nlm.nih.gov]

  • Hemoglobin SC Disease

    However, in such cases, acid electrophoresis demonstrates no abnormal hemoglobin in the HbC position.[path.upmc.edu] Too much hemoglobin C can reduce the number and size of red blood cells in your body, causing mild anemia.[stjude.org] DMCA Pulmonary Hypertension and Cor Pulmonale during Severe Acute Chest Syndrome in Sickle Cell Disease by Mekontso Dessap, Rusel Leon, Anoosha Habibi, Ruben Nzouakou, Francxoise[citeseerx.ist.psu.edu]

  • Hemoglobinopathy

    It is estimated that approximately 2 percent of African-Americans possess one gene for C hemoglobin. This is usually demonstrated on hemoglobin electrophoresis.[ncbi.nlm.nih.gov] A 52-year-old African-American man had a mild anemia (hemoglobin of 103 g/L) and target cells on the peripheral blood smear as shown.[bloodjournal.org] Abstract A Hungarian-American kindred with familial primary pulmonary hypertension (PPH) and a new, low-oxygen affinity beta-chain variant hemoglobin, Hb Washtenaw, is described[ncbi.nlm.nih.gov]

  • Alpha-Thalassemia

    […] in Alkaline Electrophoresis Normal Hemoglobin Electrophoresis Sample Alkaline Hemoglobin Electrophoresis Densitometer Tracings In what order do normal and abnormal hemoglobins[medialabinc.net] The heterozygous form may be asymptomatic or marked by mild anemia. β-thalassemia ( beta-thalassemia ) that caused by diminished synthesis of beta chains of hemoglobin.[medical-dictionary.thefreedictionary.com] A newborn with homozygous alpha-thalassemia presented with intrauterine growth retardation and presumed persistent pulmonary hypertension.[ncbi.nlm.nih.gov]

  • Hemoglobin C Disease

    Laboratory studies The following laboratory studies should be done when Hemoglobin C disease is suspected: Hemoglobin electrophoresis: To further evaluate the abnormality,[symptoma.com] All patients without tricuspid regurgitation had a measurable pulmonary regurgitation velocity or pulmonary acceleration time; none of these patients had pulmonary hypertension[haematologica.org] In electrophoresis, an electrical current is used to separate the different types of hemoglobin and thus detect abnormal hemoglobin.[msdmanuals.com]

  • Cooley's Anemia

    An additional test called a hemoglobin electrophoresis helps to further identify the abnormal hemoglobin that is typical of this type of thalassemia .[medigoo.com] People with Cooley's anemia make less hemoglobin and fewer circulating red blood cells than normal, which results in mild or severe anemia.[blood.emedtv.com] hypertension, and infertility) and promising progress towards the ultimate magic bullet—a cure in the form of bone marrow and cord blood transplants, or gene therapy.[wiley.com]

  • Haemoglobin E Disease

    Hemoglobin S and hemoglobin C are the most common types of abnormal hemoglobin that may be found by an electrophoresis test.[northshore.org] Homozygotes display mild hemolytic anemia and splenomegaly (enlarged spleen). The HbCSpr trait is asymptomatic.[wikilectures.eu] Studies indicated that hypercoagulation to pulmonary hypertension, non-healing ulcers to paravertebral haematopoietic islands are complications, very commonly detected in[omicsonline.org]

  • Hemoglobin E-Thalassemia

    Usually the diagnosis is confirmed by a blood test called a hemoglobin electrophoresis and/or a DNA test for abnormal hemoglobin genes.[kidshealth.org] Homozygous HbE is common in Southeast Asia and presents with very mild anemia, seldom requiring transfusion.[labce.com] […] artery systolic pressure (PASP) and 6-minute walk distance after 1 year of follow-up in hemoglobin E/β thalassemia (E/β-Thal) with pulmonary arterial hypertension (PAH) patients[dovepress.com]

  • Sickle Cell-Hemoglobin E Disease Syndrome

    Hemoglobin electrophoresis — Determines the specific type of abnormal hemoglobin present and at what levels it exists in the blood stream.[upmc.com] In Hgb E trait (Hgb AE) the anemia is mild with microcytosis (Hgbª12; MCV ª75) and occasional targets.[med-ed.virginia.edu] Prevalence and Severity of Pulmonary Hypertension Figure 1. Figure 1.[nejm.org]

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