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5,137 Possible Causes for Hemoglobinuria, Malaise, Progressive or Intermittent Jaundice

  • Autoimmune Hemolytic Anemia

    March hemoglobinuria Paroxysmal cold hemoglobinuria Type 1 Excludes hemoglobinuria NOS ( R82.3 ) Use Additional code (Chapter 20) to identify external cause D59.6 ) The following[icd10data.com] […] anemia with a high ferritin level is very rare and validity of serum ferritin as an important biomarker has not been used frequently. 18-year-old girl presented with fever, malaise[ncbi.nlm.nih.gov] Classifications of AIHA include warm AIHA, cold agglutinin syndrome, paroxysmal cold hemoglobinuria, mixed-type AIHA, and drug-induced AIHA.[ncbi.nlm.nih.gov]

    Missing: Progressive or Intermittent Jaundice
  • Malaria

    Hemoglobinuria (blackwater fever), a darkening of the urine seen with severe RBC hemolysis, results from high parasitemia and is often a sign of impending renal failure and[emedicine.com] The protean and nonspecific clinical findings occurring in malaria (fever, malaise, headache, myalgias, jaundice and sometimes gastrointestinal symptoms of nausea, vomiting[ncbi.nlm.nih.gov] Malaria is a mosquito-borne parasitic infection, characterized by fever, shaking chills, headaches, muscle pains, nausea, general malaise, and vomiting (1).[ncbi.nlm.nih.gov]

    Missing: Progressive or Intermittent Jaundice
  • Plasmodium Falciparum Malaria

    In severe disease, intravascular hemolysis in the kidney can cause hemoglobinemia and hemoglobinuria and dark colored urine called blackwater fever.[atsu.edu] A 32-year-old male patient presented with fever, shivering, malaise, and loss of appetite. He had travelled to West Africa.[ncbi.nlm.nih.gov] In general, patients experience flu-like symptoms like malaise, headaches, loss of appetite, myalgia and limb pain as well as nausea and vomiting during the prodromal phase[symptoma.com]

    Missing: Progressive or Intermittent Jaundice
  • Hemolytic Uremic Syndrome

    Anemia, edema, oliguria, hemoglobinuria and hypertension were the most common manifestations.[ncbi.nlm.nih.gov] On day 15, after the beginning of plasma exchange, the patient suffered a sudden malaise with neck pain.[doi.org] Effect of eculizumab on hemolysis and transfusion requirements in patients with paroxysmal nocturnal hemoglobinuria.[dx.doi.org]

    Missing: Progressive or Intermittent Jaundice
  • Hemolytic Transfusion Reaction

    A patient with phenotype R2r and anti-C has a hemolytic transfusion reaction (HTR) with hemoglobinemia and hemoglobinuria which occurred within 2 h of receiving an R1r transfusion[ncbi.nlm.nih.gov] Each presented with fever and hemoglobinuria. All but 1 patient experienced pain initially ascribed to vaso-occlusive crisis.[ncbi.nlm.nih.gov] Pink, red, brown or yellow color of plasma suggests hemolysis and hemoglobinemia, while red urine after centrifugation signifies hemoglobinuria.[symptoma.com]

    Missing: Progressive or Intermittent Jaundice
  • Anemia

    […] thrombocytopenic purpura (TTP), hemolytic uremic syndrome, aortic valve prosthesis, disseminated intravascular coagulation (DIC), cold agglutinin disease, and paroxysmal cold hemoglobinuria[emedicine.com] Others with anemia may feel: Tired Fatigue easily Appear pale Develop palpitations (feeling of heart racing) Become short of breath Additional symptoms may include: Hair loss Malaise[medicinenet.com] Spanish Hemolytic Anemia (National Heart, Lung, and Blood Institute) Iron-Deficiency Anemia (National Heart, Lung, and Blood Institute) Also in Spanish Paroxysmal Nocturnal Hemoglobinuria[medlineplus.gov]

    Missing: Progressive or Intermittent Jaundice
  • Transfusion Reaction

    During red cell transfusion, he developed hemoglobinuria. Transfusion reaction workup was negative.[ncbi.nlm.nih.gov] Allergic TR do neither cause hemolysis nor hemoglobinuria and this also applies to anaphylactic reactions.[symptoma.com] In anesthetized or comatose patients, the onset of unexplained oozing from venipuncture sites and the appearance of hemoglobinuria may be the only signs.[enotes.tripod.com]

    Missing: Progressive or Intermittent Jaundice
  • Serum Sickness

    Symptoms included disabling joint pain, proteinuria, fever, rash, and malaise.[ncbi.nlm.nih.gov] Clinical manifestations are similar to those of serum sickness, with fever, malaise, and cutaneous eruption. However, on laboratory workup, complement levels are normal.[ncbi.nlm.nih.gov] A 62-year-old patient came to the emergency room complaining of sudden malaise, chills, fever, headache, cervical lymph node enlargement, arthromyalgia, generalized purpura[ncbi.nlm.nih.gov]

    Missing: Progressive or Intermittent Jaundice
  • Babesiosis

    Babesia are transmitted by ixodid ticks and infection of the host causes a host-mediated pathology and erythrocyte lysis, resulting in anemia, hyperbilirubinuria, hemoglobinuria[ncbi.nlm.nih.gov] Symptoms typically present 1 to 6 weeks after inoculation, with the gradual onset of fatigue, malaise, weakness, and intermittent or sustained fever as high as 40.9 C.[ncbi.nlm.nih.gov] Infection of the human host can cause a very severe host-mediated pathology including fever, and hemolysis leading to anemia, hyperbilirubinuria, hemoglobinuria and possible[ncbi.nlm.nih.gov]

    Missing: Progressive or Intermittent Jaundice
  • Acquired Hemolytic Anemia

    Paroxysmal Nocturnal Hemoglobinuria: A Chronic Rare Acquired Hemolytic Anemia in a Middle-aged Female with Thrombotic Complications and Multi-system Involvement.[banglajol.info] Warm autoimmune hemolytic anemia can present as short episodes of anemia, jaundice or may progress to an intermittent chronic pattern. Spleen may become enlarged.[ispub.com] Attacks are precipated on exposure to cold and assoc with hemoglobinemia, hemoglobinuria, chills and fever, back, leg and abdominal pain, headache and malaise. 42.[slideshare.net]

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