Create issue ticket

55 Possible Causes for Hemolysis, Polychromasia in Peripheral Blood Smear

  • Zieve's Syndrome

    Lab studies revealed hemolysis as the cause of anemia. The patient was diagnosed with Zieve's syndrome and managed with supportive measures.[ncbi.nlm.nih.gov] The peripheral blood smear revealed polychromasia and nucleated erythrocytes. The parents’ blood counts and smears were normal.[indianpediatrics.net] Discussion The mechanism of hemolysis in Zieve's syndrome is not entirely understood, but alterations in red cell metabolism such as pyruvate kinase instability leave erythrocytes[ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    Laboratory investigations were suggestive of intravascular hemolysis, and on immuno-hematological evaluation it was diagnosed that the patient had autoantibody with mimicking[ncbi.nlm.nih.gov] Peripheral blood smear showed polychromasia and spherocytosis. Haptoglobin level was 0.06 g/L ( N 0.16-2). Both hemoglobin electrophoresis and G6PD level were normal.[jahjournal.org] All patients had resolution or marked improvement of hemolysis after discontinuation of maintenance of CNI and initiation of sirolimus immunosuppression.[ncbi.nlm.nih.gov]

  • Congenital Dyserythropoietic Anemia Type 1

    […] endogenous carbon monoxide production as an index of total heme turnover and the erythrocyte 51 Cr survival as an index of peripheral destruction, significant erythrocyte hemolysis[annals.org] Anisopoikilocytosis with tear-drop forms, polychromasia, basophilic stippling in peripheral blood smear, erythroid hyperplasia with megaloblastoid changes, binucleated cells[unboundmedicine.com] Anemia at birth (Hb blood loss, hemolysis or impaired red cell productio n.[oncologynurseadvisor.com]

  • Paroxysmal Cold Hemoglobinuria

    2015 ICD-9-CM Diagnosis Code 283.2 Hemoglobinuria due to hemolysis from external causes 2015 Billable Thru Sept 30/2015 Non-Billable On/After Oct 1/2015 ICD-9-CM 283.2 is[icd9data.com] Tests include complete blood count (CBC) and peripheral smear.[emedicine.com] The complete blood count usually shows normocytic anemia. Reticulocytosis may be subtle in the acute phase. Peripheral blood smear may show corresponding polychromasia.[en.wikipedia.org]

  • Cold Agglutinin Disease

    Abstract Cold agglutinin disease is a form of direct, extravascular, antiglobulin-positive hemolysis.[ncbi.nlm.nih.gov] Reticulocytes and Spherocytes The results of the reticulocyte count are usually increased in patients with cold agglutinin disease, with polychromasia in the peripheral blood[web.archive.org] Other laboratory findings include reticulocytosis, positive DAT, auto agglutination and/or rouleaux on peripheral blood smear, polychromasia, and mild to moderate anisocytosis[keralamedicaljournal.com]

  • Acquired Hemolytic Anemia

    ., some drugs and other ingested substances lead to hemolysis by direct action on RBCs, e.g., ribavirin ) Toxins (e.g., snake venom; plant poisons such as aesculin) Trauma[en.wikipedia.org] blood smear : spherocytes, polychromasia Coombs test : positive Cold agglutinins titer C3 and C4 ; (due to complement activation) Prognosis: spontaneous remission within[amboss.com] After birth and after successful therapy of hemolysis, cytomegalovirus was not detected in the plasma, strongly suggesting a causal relationship between the hemolysis and[link.springer.com]

  • Atypical Hemolytic Uremic Syndrome

    Mechanical hemolysis is a frequent but usually harmless complication of aortic valve replacement. The most common reason is valvular leakage.[ncbi.nlm.nih.gov] Anisocytosis, poikilocytosis, polychromasia, helmet cells, marked schistocytes, and rare platelets were observed in the peripheral blood smear, compatible with microangiopathic[ziaristionline.ro] Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterized by hemolysis, thrombocytopenia, and renal dysfunction.[ncbi.nlm.nih.gov]

  • Nonimmune Hemolysis

    […] acquired forms of thalassemia or erythrocytic membrane disorders, and hemolysis secondary to a dysfunctioning artificial (prosthetic) cardiac valve.[ncbi.nlm.nih.gov] blood smear : spherocytes, polychromasia Coombs test : positive Cold agglutinins titer C3 and C4 ; (due to complement activation) Prognosis: spontaneous remission within[amboss.com] […] and extravascular hemolysis, and renal failure.[nature.com]

  • Microangiopathic Hemolytic Anemia

    We postulate that in this case the inability to detect schistocytes in the peripheral smear reflected a low degree of hemolysis.[ncbi.nlm.nih.gov] The peripheral blood smear revealed polychromasia, poikilocytosis, and many schistocytes. Bone marrow biopsy disclosed metastatic carcinoma.[ncbi.nlm.nih.gov] Hemosiderinuria is seen in chronic intravascular hemolysis. 4) Examination of blood smear: Careful examination of peripheral blood smear by an experienced person provides[bioline.org.br]

  • Congenital Hemolytic Anemia

    Chronic hemolysis often results in the formation of gallstones, and cholecystectomy is often indicated.[ohsu.pure.elsevier.com] Laboratory The review of the peripheral blood smear revealed no evidence of the schistocytes or fragmented red cells.[medcraveonline.com] Early phenobarbital treatment may prevent the development of cholelithiasis in patients with chronic hemolysis.[ncbi.nlm.nih.gov]

Further symptoms

Similar symptoms