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1,456 Possible Causes for Hemolytic Anemia, Hepatosplenomegaly

  • Infectious Mononucleosis

    Both cases involved young adults presenting with fever, pharyngitis, lymphadenopathy, hepatosplenomegaly, and atypical lymphocytosis confirmed by serologic tests, liver biopsy[ncbi.nlm.nih.gov] To our knowledge, this is the first case report in the literature of this specific constellation of findings, with infectious mononucleosis, warm antibody hemolytic anemia[ncbi.nlm.nih.gov] A 17-year-old boy with Epstein-Barr virus related infectious mononucleosis and cold antibody-mediated autoimmune hemolytic anemia with incidentally noted multiple pulmonary[ncbi.nlm.nih.gov]

  • Otitis Media

    Bowel sounds present in all 4 quadrants, no hepatosplenomegaly MSK: Full range of motion in all extremeties Comparing the left and right sides of the ear helps in pinpointing[npstudent.com] Rare, but serious reactions, including hemolytic anemia, crystalluria, Stevens-Johnson Syndrome. Most common side effects are nausea, vomiting, rash.[emedexpert.com]

  • Castleman Disease

    For multicentric disease: multi-region CT bilateral hilar and mediastinal lymphadenopathy centrilobular nodules diffuse abdominal lymphadenopathy hepatosplenomegaly ascites[radiopaedia.org] anemia, bone marrow insufficiency, pulmonary, renal, hepatic, and gastrointestinal involvement, emphasizing the difficulty in diagnosis and treatment approach.[ncbi.nlm.nih.gov] […] in the groin , neck , or armpit Unintentional loss of weight In some cases fever and weakness Easy fatigue Appetite loss or extremely poor appetite Lymph node enlargement Hepatosplenomegaly[epainassist.com]

  • Multicentric Castleman's Disease

    Multicentric Castleman's disease (MCD) typically presents with constitutional symptoms, generalized peripheral lymphadenopathy, hepatosplenomegaly, and laboratory markers[ncbi.nlm.nih.gov] anemia , and immune thrombocytopenic purpura (ITP). [4] Last updated: 6/25/2015 In about half of people with multicentric Castleman disease (MCD), it is caused by human herpesvirus[rarediseases.info.nih.gov] It manifests by fever, diffuse lymphadenopathy, hepatosplenomegaly, Involvement of the respiratory system and increased C-reactive protein.[orpha.net]

  • Pyruvate Kinase Deficiency

    A case of congenital pyruvate kinase deficiency manifested at antenatal ultrasound as isolated hepatosplenomegaly is reported and the differential diagnosis is discussed.[ncbi.nlm.nih.gov] Hemolytic anemia due to deficiency of erythrocytic pyruvate kinase is a rare autosomal recessive disorder.[ncbi.nlm.nih.gov] The patients presented with severe haemolysis, progressive cholestasis, and hepatosplenomegaly, and both patients ultimately developed liver failure at a very young age.[ncbi.nlm.nih.gov]

  • Q Fever

    The patient had a new onset of Melody valve dysfunction associated with the combination of hepatosplenomegaly and pancytopenia but was afebrile.[ncbi.nlm.nih.gov] Meningoencephalitis, thyroiditis, pericarditis, myocarditis, mesenteric lymphadenopathy, hemolytic anemia, and nephritis are rare manifestations.[ncbi.nlm.nih.gov] CBC may show hemolytic anemia WBC Liver function may show mild elevation of transaminase ESR may be elevated Blood cultures are usually negative Lumbar puncture to sample[symptoma.com]

  • Niemann-Pick Disease

    Hepatosplenomegaly is a hallmark of both types of NPD and lymphadenopathy may occur in patients with type B.[symptoma.com] anemias attributable to enzyme disorders ( D55.- ) Marfan's syndrome ( Q87.4 ) 5-alpha-reductase deficiency ( E29.1 ) Metabolic disorders E75 ICD-10-CM Diagnosis Code E75[icd10data.com] These patients may have mild hepatosplenomegaly, but the central nervous system is profoundly affected.[ncbi.nlm.nih.gov]

  • Familial Hemophagocytic Lymphohistiocytosis

    Reported here is the case of a 12-year-old boy, from a poor family, with a 6-year history of visual loss and fever for 5 months, and transient hemiparesis with hepatosplenomegaly[ncbi.nlm.nih.gov] This case report highlights the difficulty in managing posttransplant autoimmune hemolytic anemia.[ncbi.nlm.nih.gov] Examination revealed fever, lymphadenopathy, and hepatosplenomegaly. Ultrasound examination revealed hepatosplenomegaly and free intra-abdominal fluid.[ncbi.nlm.nih.gov]

  • Thalassemia

    They have severe anemia and hepatosplenomegaly. Untreated children have severe failure to thrive and shortened life expectancy.[meddean.luc.edu] Though hypertriglyceridemia has been reported with hemolytic anemias, the mechanism is unclear.[ncbi.nlm.nih.gov] Here, we report a novel mutation in a patient from Thailand who presented with chronic hemolytic anemia.[ncbi.nlm.nih.gov]

  • Wilson Disease

    He was deeply icteric with ascites, hepatosplenomegaly, hyperbilirubinemia, raised transaminases, and coagulopathy.[ncbi.nlm.nih.gov] Although fulminant hepatitis with nonimmune hemolytic anemia is frequently reported, chronic mild hepatitis can occur with bouts of transient hemolytic anemia.[ncbi.nlm.nih.gov] Chronic liver disease with portal hypertension, hepatosplenomegaly, ascites, low serum albumin concentration, and coagulopathy Fatty liver of mild to moderate degree with[ncbi.nlm.nih.gov]

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