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1,827 Possible Causes for Hemorrhage, Petechiae, Platelet Count Normal, Purpura

  • Glanzmann Thrombasthenia

    Symptoms include purpura, petechiae, bruising, gingival bleeding, epistaxis, and menorrhagia.[ncbi.nlm.nih.gov] Patient with Glanzmann thrombasthenia may present with normal platelet count, normal activated partial thromboplastin time and normal prothrombin time.[medicalrealm.net] […] recessive coagulopathy characterized by either qualitative or quantitative abnormalities of the membrane glycoprotein αIIbβ3 complex leading to bleeding tendencies, ranging from purpura[ncbi.nlm.nih.gov] Glanzmann thrombasthenia is a rare disorder of platelet function that may result in life-threatening hemorrhage, particularly from the nasal vaults.[ncbi.nlm.nih.gov]

  • Hemophilia

    Primary Hemostasis – Platelet aggregation forms an initial plug (immediate) – Deficiencies tend to cause superficial bleeds (i.e petechiae, ecchymosis, & purpura) Secondary[rebelem.com] A normal platelet count , normal PT, and a prolonged aPTT are characteristic of hemophilia A and hemophilia B.[medicinenet.com] Subgaleal hemorrhage is a rare but potentially fatal birth trauma.[ncbi.nlm.nih.gov] Petechiae are characteristically absent. There is massive hemorrhage following trauma.[symptoma.com]

  • Hemophilia B

    Petechiae usually do not occur in patients with hemophilia because they are manifestations of capillary blood leaking, which is typically the result of vasculitis or abnormalities[emedicine.medscape.com] Persons with hemophilia A and B have a normal platelet count and normal PT, but have a prolonged aPTT.[symptoma.com] ICD-10-CM Codes › D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism › D65-D69 Coagulation defects, purpura and other[icd10data.com] Even if bleeding occurs, it rarely becomes life-threatening, such as in intracranial hemorrhage (ICH).[ncbi.nlm.nih.gov]

  • Piperacillin

    Physical examination revealed multiple bruises over puncture sites and petechiae over bilateral lower extremities.[ncbi.nlm.nih.gov] After piperacillin was discontinued, the platelet counts became normal.[ncbi.nlm.nih.gov] The patient was diagnosed with thrombotic thrombocytopenic purpura (TTP) on the basis of thrombocytopenia, MAHA, renal dysfunction, fever, and neurological abnormalities.[ncbi.nlm.nih.gov] Clinically significant hemorrhage associated with extended spectrum anti-Pseudomonas penicillins is uncommon.[ncbi.nlm.nih.gov]

  • Hemophilia A

    Because platelets are unaffected patients with Hemophilia A do not display petechiae.[pathwaymedicine.org] Interpretation of Initial Tests Hemophilia A or B a,b VWD Platelet Defect Platelet count Normal Normal or reduced Normal or reduced PT Normal Normal Normal PTT Prolonged c[arupconsult.com] Soft tissue bruising (purpura) over trunk or extremities in an otherwise healthy person (particularly male), without accompanying systemic signs such as fever should prompt[cancertherapyadvisor.com] Subgaleal hemorrhage is a rare but potentially fatal birth trauma.[ncbi.nlm.nih.gov]

  • Meningococcemia

    Petechiae are the most common cutaneous sign, seen in one-third to one-half of affected patients.[visualdx.com] This report describes a patient with meningococcemia who presented with an atypical erythematous patch over the right hemithorax, petechial rash, and a normal platelet count[ncbi.nlm.nih.gov] To evaluate the clinical and laboratory effects of protein C concentrate as an adjunct to conventional therapy in the treatment of meningococcemia with purpura fulminans.[ncbi.nlm.nih.gov] Two cases of adrenal hemorrhage in meningococcemia detected by ultrasound are reported.[ncbi.nlm.nih.gov]

  • Vitamin K Deficiency

    Infants with vitamin K deficiency present with hemorrhagic disease of the newborn at days 1-7 of life with intracranial or retroperitoneal hemorrhage, petechiae, or mucosal[visualdx.com] Platelet counts are within the normal range, regarding function, however, neonatal platelets seem to be hyporeactive.[ncbi.nlm.nih.gov] Nodular purpura in infancy. Postgrad Med J 1982;58:274-8. [ PUBMED ] 4. Baselga E, Drolet BA, Esterly NB. Purpura in infants and children.[e-ijd.org] Hemorrhage was determined on the right adrenal gland with abdominal ultrasonography and computerized tomography.[ncbi.nlm.nih.gov]

  • Brucellosis

    An 8-year-old boy was admitted with recurrent epistaxis, petechiae and purpura on face and extremities and bleeding from the gums.[ncbi.nlm.nih.gov] Henoch-Schönlein purpura (HSP) is the most common vasculitis of childhood.[ncbi.nlm.nih.gov] Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease caused by a virus that is transmitted to humans by ixoid tick bites, contact with blood and tissue of infected[ncbi.nlm.nih.gov] Three of the 11 patients had severe thrombocytopenia, and they were admitted with complaints of epistaxis, gingival bleeding, petechiae, and purpura.[ncbi.nlm.nih.gov]

  • Von Willebrand Disease

    platelet count, normal clot retraction, partial and variable deficiency of factor VIIIR.[medical-dictionary.thefreedictionary.com] An infant with presumed maternal immune thrombocytopenic purpura had persistent thrombocytopenia with platelet clumping.[ncbi.nlm.nih.gov] The examiner should note the size, location, and distribution of any ecchymoses, hematomas, or petechiae, and should assess for evidence of risks of increased bleeding, such[emedicine.medscape.com] This is the first case reported to have intraretinal hemorrhage only as the first manifestation of VWD type 1.[ncbi.nlm.nih.gov]

  • Dengue Hemorrhagic Fever

    In the course of the co-infection, he developed fever, thrombocytopenia (13,700 cells/mm3), petechia, and hypoalbuminemia, which are compatible with the World Health Organization[ncbi.nlm.nih.gov] Day 0 indicates the date of administration of WinRho SDF. 48 hours after administration of WinRho SDF, the platelet count returned to normal ( 150,000) in all patients.[bloodjournal.org] Hemorrhagic manifestations are fairly common in Dengue hemorrhagic fever and are associated with increased mortality.[ncbi.nlm.nih.gov] We present a 51 year old male who presented with fever, petechiae and acute onset of breathlessness.[ncbi.nlm.nih.gov]

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