Hepatocellular Carcinoma: Causes & Reasons

Possible Causes for Hepatocellular Carcinoma

It is very rare to see hepatocellular carcinoma in the absence of evidence of liver injury. [ncbi.nlm.nih.gov]

The current histological, computed tomography, and magnetic resonance imaging findings revealed hepatocellular carcinoma (HCC) and non-cirrhotic liver hemochromatosis. [ncbi.nlm.nih.gov]

Hepatocellular carcinoma (HCC) is a long-term complication of HH, which contributes to increased mortality.We evaluated the risk factors of HCC in a prospective cohort of [ncbi.nlm.nih.gov]

Portal Cirrhosis

It also addressed the efficiency of splenectomy in reducing hepatocellular carcinoma risk. [clinicaltrials.gov]

One of the key roles of diagnostic radiology is detection of hepatocellular carcinoma. [radiopaedia.org]

Hepatocellular carcinoma Cirrhosis is a major risk factor for hepatocellular carcinoma. See the separate Hepatocellular Carcinoma article [ 3 ]. [patient.info]

Neoplasm of the Liver

Hepatocellular, Hepatocellular Carcinoma, Hepatocellular Carcinomas, Hepatoma, Hepatomas, HEPATOCELLULAR CARCINOMA, LCC, LIVER CELL CARCINOMA, HCC, HEPATOMA, Hepatocellular [fpnotebook.com]

Adult Liver Cancer, Neoplasms, Hepatic, Cancer of the Liver, Hepatocellular Carcinomas, Liver Cancers, Adult, Hepatocellular Cancer, Carcinomas, Hepatocellular, Carcinoma [ebi.ac.uk]

What is hepatocellular carcinoma? [stjude.org]

Macronodular Cirrhosis

Hepatocellular carcinoma is rare in infancy. [ncbi.nlm.nih.gov]

OBJECTIVE: Patients with hepatocellular carcinoma (HCC) presenting with nonmicronodular or micronodular cirrhosis are usually treated by hepatectomy. [ncbi.nlm.nih.gov]

Hepatocellular carcinoma: pathobiology. [emedicine.medscape.com]

Cryptogenic Cirrhosis

Our aim was to assess survival and the occurrence of hepatocellular carcinoma and complications of hepatic insufficiency in obesity-related cryptogenic cirrhosis compared [ncbi.nlm.nih.gov]

carcinoma (HCC), although the clinical characteristics of HCC in these patients have not been completely defined. [ncbi.nlm.nih.gov]

Management of hepatocellular carcinoma: an update. Hepatology. 2011;53:1020–2. Asia Pacific Working Party on Prevention of Hepatocellular Carcinoma. [dx.doi.org]

Viral Hepatitis

Keywords Hepatocellular carcinoma Hepatitis B Hepatitis C Viral hepatitis Background Hepatocellular Carcinoma (HCC) is the third leading cause of cancer related mortality [bmcgastroenterol.biomedcentral.com]

PURPOSE: Liver cancer (hepatocellular carcinoma (HCC)) incidence and mortality rates are increasing in the United States. [ncbi.nlm.nih.gov]

INTRODUCTION: Hepatitis B (HBV) and C viruses (HCV) are important causes of hepatocellular carcinoma (HCC). [ncbi.nlm.nih.gov]

Chronic Hepatitis C

A 55 year old gentleman was diagnosed with hepatocellular carcinoma and concomitant chronic hepatitis C viral infection. [ncbi.nlm.nih.gov]

We report on a 62-year-old man with chronic hepatitis C who developed rapidly growing hepatocellular carcinoma (HCC) after achieving sustained virological response at post-treatment [ncbi.nlm.nih.gov]

We herein report the case of a woman in her 80s with a recurrent hepatocellular carcinoma (HCC) tumor that rapidly increased in size during direct-acting antiviral (DAA) treatment [ncbi.nlm.nih.gov]

Acute Hepatic Porphyria

carcinoma (HCC). [ajmc.com]

carcinoma, and psychological problems. [thinkporphyria.eu]

Ann Intern Med 2005; 142: 439–450 Innala E, Anderson C: Screening for hepatocellular carcinoma in acute intermittent porphyria: a 15-year follow-up in northern Sweden. [econtent.hogrefe.com]

Hepatopathy

After the patient expired due to hepatic failure, an autopsy revealed poorly differentiated hepatocellular carcinoma (HCC) surrounded by multiple hepatic cysts. [ncbi.nlm.nih.gov]

Mutational and epimutational pathway representation in hepatocellular carcinoma. [doi.org]

Hepatocellular carcinoma is cancer that starts in the liver. Hepatocellular carcinoma accounts for most liver cancers. [nlm.nih.gov]

Hepatitis B

KEYWORDS: AX800134; Hepatitis B virus; Hepatocellular carcinoma; Long non-coding RNA [ncbi.nlm.nih.gov]

BACKGROUND: Hepatitis B virus (HBV) accounts for more than 60% of hepatocellular carcinoma (HCC) cases. [ncbi.nlm.nih.gov]

BACKGROUND: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide. [ncbi.nlm.nih.gov]

Primary Biliary Cirrhosis

carcinoma-cholangiocellular carcinoma and hepatocellular carcinoma, World Journal of Hepatology, 9, 36, (1378), (2017). [doi.org]

The incidence of hepatocellular carcinoma (HCC) complicating primary biliary cirrhosis (PBC) is between 0.7% and 16%. [ncbi.nlm.nih.gov]

In this study we have determined the incidence of hepatocellular carcinoma (HCC) development in primary biliary cirrhosis (PBC) and its effects on patient survival. [ncbi.nlm.nih.gov]

Chronic Active Hepatitis B

Transforming growth factor alpha was expressed in 26 (68.4%) of 38 chronic active hepatitis B, 18 (56.3%) of 32 cirrhosis and 16 (51.6%) of 31 hepatocellular carcinoma tissue [ncbi.nlm.nih.gov]

We assumed that only patients with active viral replication would be treated and that alpha-interferon would prevent cirrhosis and hepatocellular carcinoma in a portion of [ncbi.nlm.nih.gov]

carcinoma. [library.med.utah.edu]

Hepatitis C

The presentation of primary hepatocellular carcinoma with spinal cord compression is very rare. [ncbi.nlm.nih.gov]

An 82-year-old man presented with hepatocellular carcinomas (HCCs) 24 years after achieving a sustained virological response (SVR) to an interferon for hepatitis C. [ncbi.nlm.nih.gov]

Lin HH, Liew CT, Liaw YF: Hepatocellular carcinoma presenting as acute spontaneous hemothorax. [wjso.biomedcentral.com]

Congenital Liver Cirrhosis

Hepatocellular carcinoma (HCC) is a rare complication of CHF with only a few previous cases reported. [jmedicalcasereports.biomedcentral.com]

Screening for Hepatocellular Carcinoma Also important to consider is screening for hepatocellular carcinoma. [acc.org]

One of the key roles of diagnostic radiology is detection of hepatocellular carcinoma. [radiopaedia.org]

Hepatocellular Adenoma

Telangiectatic hepatocellular adenoma is a rare, recently recognized subtype of benign liver tumor that may very rarely undergo transformation into hepatocellular carcinoma [ncbi.nlm.nih.gov]

[…] adenoma and hepatocellular carcinoma. [ncbi.nlm.nih.gov]

hepatocellular carcinoma. [link.springer.com]

Chronic Persistent Hepatitis

Furthermore, HB AG is detected in a high rate among cases with hepatocellular carcinoma suggesting the intimate causal relationship between hepatitis b virus and hepatocellular [ncbi.nlm.nih.gov]

Cost-effectiveness of sorafenib treatment in field practice for patients with hepatocellular carcinoma. Hepatology. 2013;57(3):1046–54. [doi.org]

carcinoma caused by Hepatitis C Hepatocellular carcinoma caused by Hepatitis C- higher magnification Hepatocellular carcinoma caused by Hepatitis C: gross anatomy Hepatitis-E [commons.wikimedia.org]

Chronic Active Hepatitis

We report data on decompensation, detection of hepatocellular carcinoma, and mortality rates. [ncbi.nlm.nih.gov]

Nine of 63 (14.2%) and 6/63 (9.5%) developed cirrhosis and hepatocellular carcinoma, respectively. [ncbi.nlm.nih.gov]

A 57 year old man with auto-immune chronic active hepatitis, regularly treated with immunosuppressive therapy, had hepatocellular carcinoma (HCC) 10 years after diagnosis [ncbi.nlm.nih.gov]

Alpha-1 Antitrypsin Deficiency

Cirrhosis and hepatocellular carcinoma then result in some patients. [ncbi.nlm.nih.gov]

With cirrhosis there is a risk of hepatocellular carcinoma. Investigations Serum levels of A1AT can be measured. [patient.info]

Due to increased risk of hepatocellular carcinoma, surveillance imaging and/or α-fetoprotein levels should be considered. [unboundmedicine.com]

Porphyria Cutanea Tarda

Liver fibrosis and cirrhosis are predisposing factors for the development of hepatocellular carcinoma (HCC). [ncbi.nlm.nih.gov]

Patients with severe hepatic pathology or longstanding untreated PCT need to be monitored for the development of hepatocellular carcinoma in the long term. [ncbi.nlm.nih.gov]

In the literature, concomitant presentation of porphyria with hepatocellular carcinoma is common; however, no case of porphyria cutanea tarda associated with cholangiocarcinoma [ncbi.nlm.nih.gov]

Tyrosinemia

Comprehensive proteomic profiling identifies serum proteomic signatures for detection of Hepatocellular Carcinoma and Its Subtypes. [journals.lww.com]

Hepatocellular carcinoma can usually be suspected when there are increased α 1 -fetoprotein levels and characteristic imaging features. [pediatrics.aappublications.org]

Hepatocellular carcinoma (HCC) was found either preoperatively or incidentally in five patients, all older than 2 years at the time of their transplant. [ncbi.nlm.nih.gov]

Chronic Hepatic Schistosomiasis

carcinoma, particularly secondary to the S.Mansoni subtype Promoted articles (advertising) [radiopaedia.org]

Risk factors for hepatocellular carcinoma in Egypt: the role of hepatitis-B viral infection and schistosomiasis. Anticancer Res 1999;19:4565–4569. [link.springer.com]

Transforming growth factor-alpha and epidermal growth factor receptor in chronic liver disease and hepatocellular carcinoma. [pacificejournals.com]

Hereditary Coproporphyria

In these studies, etiological factors for hepatocellular carcinoma were not completely sought. [ncbi.nlm.nih.gov]

People with repeated attacks are at risk for developing chronic renal disease and liver cancer (hepatocellular carcinoma) How is Hereditary Coproporphyria diagnosed? [porphyriafoundation.blogspot.com]

The increased predisposition for hepatocellular carcinoma is seen in various types of porphyria. [clinicaladvisor.com]

Chronic Alcoholism

Mutations, decreased promoter activity, and decreased expression in PTEN are frequently identified in patients with hepatocellular carcinoma. [ncbi.nlm.nih.gov]

Hepatocellular carcinoma was present at the time of diagnosis in 15.4% of cases. [ncbi.nlm.nih.gov]

ONCOLOGY – alcohol predisposes to multiple cancers, most notably Hepatocellular carcinoma (secondary to cirrhosis), also ENT and esophageal cancers (synergistic with smoking [errolozdalga.com]

Wilson Disease

Here, we describe a 45-year-old woman who presented with an incidental hepatocellular carcinoma at the time of transplant. [ncbi.nlm.nih.gov]

LT is also used to treat hepatocellular carcinoma when it develops in patients with WD when tumor resection is not feasible. [ncbi.nlm.nih.gov]

Our team works side by side with oncologists to care for patients with hepatocellular carcinoma (HCC) to increase treatment options and optimize survival. [northwell.edu]

Aflatoxicosis

Indeed, long-term aflatoxin exposure is linked to the development of hepatocellular carcinoma (HCC). [ncbi.nlm.nih.gov]

There is a positive association between dietary aflatoxins and hepatocellular carcinoma. [visualdx.com]

Gaucher Disease

Gaucher's disease has been correlated with cases of myeloma, leukemia, glioblastoma, lung cancer, and hepatocellular carcinoma, although the reasons for the correlation are [ncbi.nlm.nih.gov]

Arthur Zimmermann, Etiology and Pathogenesis of Hepatocellular Carcinoma: Hepatocellular Carcinoma Associated with Inborn Errors of Metabolism and Hepatobiliary Malformations [doi.org]

In addition, an increased risk has been reported for hepatocellular carcinoma and renal cell carcinoma. [doi.org]

Thalassemia

KEYWORDS: Hepatitis B virus (HBV); hepatitis C virus (HCV); hepatocellular carcinoma (HCC); iron overload; liver iron concentration (LIC); thalassemia [ncbi.nlm.nih.gov]

More aggressive approaches to the treatment of hepatitis C may be particularly valuable because of the additive risks for cirrhosis and hepatocellular carcinoma that are posed [ncbi.nlm.nih.gov]

Hepatocellular carcinoma in the thalassaemia syndromes. [ncbi.nlm.nih.gov]

Beta Thalassaemia Major

Iron overload (IO) in the liver results in liver fibrosis, cirrhosis, and eventually hepatocellular carcinoma. [ncbi.nlm.nih.gov]

Carcinoma in Thalassemia. [nyas.org]

25 PM Renal Aspects of Thalassemia Sunil Bhandari, MBChB, MRCP, FRCP, PhD, M Clin Ed, FHEA, Hull & East Yorkshire Hospitals NHS Trust & Hull York Medical School 3:50 PM Hepatocellular [nyas.org]

Anabolic Steroid

A 35-year-old male bodybuilder was found to have a hepatocellular carcinoma (HCC) arising in a pre-existing hepatic adenoma following recreational anabolic steroid use. [ncbi.nlm.nih.gov]

The histopathological findings were compatible with those of multiple hepatocellular carcinoma without liver cirrhosis. [ncbi.nlm.nih.gov]

For instance, relevant concern has been raised by the AAS hepatotoxicity including adenoma, hepatocellular carcinoma, cholestasis, and peliosis hepatis. [ncbi.nlm.nih.gov]

Beckwith-Wiedemann Syndrome

A patient with Simpson-Golabi-Behmel syndrome and hepatocellular carcinoma. J Med Genet 1998; 35 (2) 153-156 33 Morris MR, Astuti D, Maher ER. [doi.org]