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17 Possible Causes for Hepatocellular Carcinoma, Liver Biopsy showing Periportal Necrosis

  • Viral Hepatitis

    PURPOSE: Liver cancer (hepatocellular carcinoma (HCC)) incidence and mortality rates are increasing in the United States.[ncbi.nlm.nih.gov] INTRODUCTION: Hepatitis B (HBV) and C viruses (HCV) are important causes of hepatocellular carcinoma (HCC).[ncbi.nlm.nih.gov] The occurrence of hepatocellular carcinoma (HCC) in renal transplant recipients has typically been associated with hepatitis B or C infection.[ncbi.nlm.nih.gov]

  • Hepatitis B

    KEYWORDS: AX800134; Hepatitis B virus; Hepatocellular carcinoma; Long non-coding RNA[ncbi.nlm.nih.gov] Dermatomyositis or polymyositis as a paraneoplastic syndrome of hepatocellular carcinoma (HCC) is an uncommon event. Few cases have been reported in the literature.[ncbi.nlm.nih.gov] BACKGROUND: Hepatitis B virus (HBV) accounts for more than 60% of hepatocellular carcinoma (HCC) cases.[ncbi.nlm.nih.gov]

  • Aflatoxicosis

    Indeed, long-term aflatoxin exposure is linked to the development of hepatocellular carcinoma (HCC).[ncbi.nlm.nih.gov] There is a positive association between dietary aflatoxins and hepatocellular carcinoma.[visualdx.com]

  • Primary Sclerosing Cholangitis

    The patient's explanted liver showed changes of PSC affecting only the small- and medium-sized bile ducts in addition to three incidental nodules of hepatocellular carcinoma[ncbi.nlm.nih.gov] Surveillance for GBCa is recommended, but the clinical utility of surveillance for other hepatobiliary cancers (HBCa) in PSC, namely CCA and hepatocellular carcinoma (HCC)[ncbi.nlm.nih.gov] KEYWORDS: cancer surveillance; cholangiocarcinoma; cirrhosis; colorectal cancer; gallbladder cancer; hepatocellular carcinoma; primary sclerosing cholangitis[ncbi.nlm.nih.gov]

  • Massive Hepatic Necrosis

    A, intraoperative (POD 0) wedge biopsy of the native liver showed massive hepatic necrosis and periportal ductular structure (HE, 200 ).[nature.com] Hepatic necrosis after ethanol ablation for hepatocellular carcinoma (HCC), although rare, is well known and described, particularly in patients with chronic liver disease[ncbi.nlm.nih.gov] More than half of hepatocellular carcinoma and a part of cholangiocarcinoma derive from liver cirrhosis.[w2.umm.de]

  • Isoniazid Hepatitis

    Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa. ‎[books.google.com]

  • Primary Biliary Cirrhosis

    Liver biopsy showed lymphocytic and plasmacytic infiltration in the portal and periportal areas, with numerous areas of bridging centrilobular necrosis, indicating AIH.[ncbi.nlm.nih.gov] carcinoma-cholangiocellular carcinoma and hepatocellular carcinoma, World Journal of Hepatology, 9, 36, (1378), (2017).[doi.org] The incidence of hepatocellular carcinoma (HCC) complicating primary biliary cirrhosis (PBC) is between 0.7% and 16%.[ncbi.nlm.nih.gov]

  • Hepatitis A

    KEYWORDS: Focal liver injury; Focal liver reaction; Hepatocellular carcinoma; Pathology; Radiation-induced liver disease; Threshold dose[ncbi.nlm.nih.gov] HBV and HCV can persist as chronic infections and represent a leading cause of chronic liver disease and hepatocellular carcinoma in the United States.[ncbi.nlm.nih.gov] High serum hepatitis B viral levels are associated with an increased risk of progression to cirrhosis and hepatocellular carcinoma; experts and guidelines have endorsed maximal[depts.washington.edu]

  • Chronic Active Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] We report data on decompensation, detection of hepatocellular carcinoma, and mortality rates.[ncbi.nlm.nih.gov] Nine of 63 (14.2%) and 6/63 (9.5%) developed cirrhosis and hepatocellular carcinoma, respectively.[ncbi.nlm.nih.gov]

  • Chronic Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] Chronic hepatitis B virus (HBV) infection increases the risk of developing cirrhosis and hepatocellular carcinoma (HCC) with suspected interactions between virus replication[ncbi.nlm.nih.gov] Ito K, Mitchell DG, Gabata T, et al: Hepatocellular carcinoma: Association with increased iron deposition in the cirrhotic liver at MR imaging.[doi.org]

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