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345 Possible Causes for Hepatomegaly, Immunodeficiency Is Progressive, Leukocytosis

  • Infectious Mononucleosis

    The patient showed severe hepatomegaly incidentally, and dual positivity of Immunoglobulin (Ig) M to Epstein-Barr virus (EBV) viral capsid antigen (VCA) and cytomegalovirus[ncbi.nlm.nih.gov] A major obstacle to understanding these sequelae has been the lack of an efficient animal model for EBV infection, although progress in primate and mouse models has recently[ncbi.nlm.nih.gov] Sprunt, Frank Alexander Evans (1889-1956): Mononuclear leukocytosis in reaction to acute infection (infectious mononucleosis).[whonamedit.com]

  • Toxoplasmosis

    […] common encephalomyelitis, retinochoroiditis, intracranial calcification and hydrocephalus to the non-specific symptoms of acute infection such as convulsion, splenomegaly, hepatomegaly[fao.org] In immunodeficient individuals and in some apparently immunologically healthy patients, the acute infection progresses, resulting in potentially lethal consequences such as[emedicine.medscape.com] There may be ventriculomegaly, CNS calcifications, placental changes, hepatomegaly, splenomegaly, ascites and pericardial or pleural effusion [ 3 ] .[patient.info]

  • Adult-Onset Still Disease

    Liver involvement was observed in all cases, with hepatomegaly in 81.3%, increased liver enzymes in 50.0%, and hypergammaglobulinemia in 68.8%.[ncbi.nlm.nih.gov] Collapsing glomerulopathy is a new pattern of renal disease that emerged with the human immunodeficiency virus (HIV) epidemic in the 1970s—HIV-associated nephropathy.[rheumatology.oxfordjournals.org] AOSD) is a systemic inflammatory disease characterized by high-fevers, articular involvement, maculopapular rash, hepatosplenomegaly, lymphadenopathy, and a neutrophilic leukocytosis[ncbi.nlm.nih.gov]

  • Chronic Myeloid Leukemia

    Hepatomegaly also occurs, although less commonly than splenomegaly. Hepatomegaly is usually part of the extramedullary hematopoiesis occurring in the spleen.[emedicine.medscape.com] According to some investigators there is a reservoir of primitive progenitors that are capable of self-renewal or progression in vitro or in vivo in immunodeficient mice.[intechopen.com] Her disease was managed during pregnancy using interferon-α alone despite persistent leukocytosis.[ncbi.nlm.nih.gov]

  • Familial Myelofibrosis

    In case of hepatomegaly, the liver extends to more than 3 cm below the right costal margin of the newborn.[symptoma.com] A correlation between leukocytosis and risk of acute leukemia has been recently reported in patients with PV. 24 These data indicate that PV patients with leukocytosis are[bloodjournal.org] Cladribine This purine analogue, previously known as 2‐chlorodeoxyadenosine, has been shown to reduce clinically significant post‐splenectomy hepatomegaly and post‐splenectomy[onlinelibrary.wiley.com]

  • Chronic Phase of Chronic Myeloid Leukemia

    CP-CML patients are generally asymptomatic and diagnosis of the disease is based on the incidental detection of hematological alterations: While leukocytosis 50*10 9/l is[symptoma.com] Hepatomegaly. Enlarged lymph nodes are also a possibility. Anaemia can produce a hyperdynamic circulation. Easy bruising. Fever. Gout due to rapid cell turnover.[patient.info] According to some investigators there is a reservoir of primitive progenitors that are capable of self-renewal or progression in vitro or in vivo in immunodeficient mice.[intechopen.com]

  • Hairy Cell Leukemia

    Hepatomegaly and liver dysfunction may be found in 20% of patients.[symptoma.com] It usually develops In patients with an underlying immunodeficiency.[ncbi.nlm.nih.gov] The 3 HCL-v patients had leukocytosis and received chemotherapy with variable outcome.[ncbi.nlm.nih.gov]

  • Amebiasis

    Amebiasis should be considered in the differential diagnosis of infants and children with hematochezia or hepatomegaly, especially in endemic areas.[ncbi.nlm.nih.gov] Coinfection with other pathogens increases the likelihood of progression of HIV/acquired immunodeficiency syndrome (AIDS), and the immunosuppressive consequences of the disease[ncbi.nlm.nih.gov] High fever, leukocytosis and high CRP were associated with extraluminal amebic diseases.[ncbi.nlm.nih.gov]

  • Systemic Amyloidosis

    Examination and tests in this patient also revealed anemia, hepatomegaly, infiltrative cardiomyopathy, polyneuropathy and immunoglobulin l deposition, favoring a diagnosis[ncbi.nlm.nih.gov] Guy Pratt, Oliver Goodyear and Paul Moss, Immunodeficiency and immunotherapy in multiple myeloma, British Journal of Haematology, 138, 5, (563-579), (2007). O.[doi.org] Key words: AL Amyloidosis, Proteinuria, Hepatomegaly Advertisement Journal of Contemporary Medical Education SUBMIT YOUR ARTICLE NOW[scopemed.org]

  • Pediatric Chronic Granulomatous Disease

    […] nitro blue tetrazolium test (almost always positive) Clinically, patients have recurrent lymphadenitis, hepatosplenomegaly, skin rash, pulmonary edema Laboratory Anemia, leukocytosis[pathologyoutlines.com] […] pneumonias aspergillosis skin abscesses pulmonary abscesses chronic diarrhea ear infections osteomyelitis failure to thrive Physical exam short stature eczematoid dermatitis hepatomegaly[medbullets.com] Failure of adequate therapy for acute community-acquired pneumonia and rapid progression to respiratory failure should lead to the possibility of fungal etiology.[ncbi.nlm.nih.gov]

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