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21 Possible Causes for Hepatomegaly, Intermittent Jaundice, Uric Acid Increased

  • Hereditary Spherocytosis

    Pallor (100%), icterus (67%), undocumented fever (28%), splenomegaly (96%) and hepatomegaly (73%) were the most frequent findings. Cholelithiasis was observed in 26%.[] Abstract Hereditary spherocytosis is an autosomal dominant congenital hemolytic anemia due to defect in RBC membrane protein that commonly presents with intermittent jaundice[] Hepatomegaly may be present. Cholelithiasis (pigment stones) is common and may be the presenting symptom.[]

  • Hepatorenal Syndrome

    Sixteen variables had predictive value for hepatorenal syndrome occurrence in the univariate analysis: history of ascites, hepatomegaly, nutritional status, blood urea nitrogen[] Wui-Chiang Lee, Han-Chieh Lin, Ming-Chih Hou, Hsiao-Yi Lin, Fa-Yauh Lee, Sun-Sang Wang, Full-Young Chang and Shou-Dong Lee , Serum Uric Acid Levels in Patients With Cirrhosis[] Severe circulatory dysfunction (mean arterial pressure usually is 70 mm Hg) and very low systemic vascular resistance. • Severe liver disease, with jaundice, coagulopathy,[]

  • Primary Biliary Cirrhosis

    […] ankles Diarrhea characterized by greasy stools Ascites Skin darkening Abdominal pain experienced in the upper right region Deposition of fat in areas around eyes and eyelids Hepatomegaly[] Twenty four hour urine demonstrated a low renal fractional tubular reabsorption of phosphate, increased fractional excretion of uric acid and generalized aminoaciduria.[] Reddy AN, Grosberg SJ, Wapnick S: Intermittent cholestatic jaundice and nonmetastatic prostatic carcinoma. Arch Intern Med 1977;137:1616–1618.[]

  • Hypercholesterolemia

    ( 24 seconds, arm to tongue) Hepato-jugular reflux Autopsy shows pulmonary edema, visceral congestion, cardiomegaly Ankle edema Night cough Dyspnea on ordinary exertion Hepatomegaly[] Gout or increased uric acid.[] We report the case of a male infant who had developed failure to thrive, jaundice, intermittent pruritus, and multiple diffuse symmetrical skin xanthomas at 1 year of age.[]

  • Tyrosinemia

    The tubular handling of phosphorus, uric acid, beta 2-microglobulin, and amino acids was disturbed. Low urinary osmolality was also seen.[] We present three children, two boys and one girl, who presented with rickets and hepatomegaly.[] The acute onset may be dramatic, with hepatomegaly, jaundice, epistaxis, melaena, purpuric lesions, marked oedema, and the distinctive cabbage-like odour.[]

  • Congenital Liver Cirrhosis

    Abdominal computed tomography findings revealed Caroli’s disease and hepatomegaly accompanied by multiple renal cysts ( Fig. 2 ).[] acid level elevated Maternal mortality, 1%; prematurity and fetal death, 5%-30% Beta blocker, methyldopa, magnesium sulfate; early delivery HELLP syndrome Beyond 22 wk and[] He had intermittent high grade fever with dry cough and respiratory distress for 4 days duration.[]

  • Pericholangitis

    PH YS IC AL EX AM IN AT IO N Abnormal physical findings • Jaundice • Hepatomegaly • Splenomegaly • Ascites and edema • Spider angiomata • Leukonychia • Muscle wasting • Gynecomastia[] acid stones Migratory arthritis Sacroiliitis and ankylosing spondylitis Erythema nodosum and uveitis Complications Toxic megacolon Adenocarcinoma of the colon (1-16%) Increased[] Clinically, this condition usually manifests with chronic intermittent obstructive jaundice. Abdominal pain, pruritus, fatiguability and fever are variably present.[]

  • Refractory Megaloblastic Anemia

    . - Hepatomegaly, splenomegaly - Cirrhosis. - Diabetes.[] He has a fever and you note jaundice. You order an ultrasound of his abdomen and find multiple gallstones. Lab results: Hct .36 L/L; Hgb 120 g/L. PBS at right.[] […] degree of in effective erythropoiesis · Haptoglobins, Uric acid and alkaline phosphatase levels – Decreased. · Serum methylmalonate and homocystein levels - Vitamin B-12[]

  • Hemolytic Anemia due to a Disorder of Glycolytic Enzymes

    However, inosine, which is a naturally occurring substance, increases plasma uric acid levels ( 38 ).[] In early childhood, patients will present with hepatomegaly, hypoglycemia and ketotosis.[] jaundice and episodes of red/ dark urine Venous thrombosis in unusual locations (e.g., hepatic, cerebral, abdominal veins) Vasoconstriction : headache, pulmonary hypertension[]

  • Progressive Retinal Dystrophy due to Retinol Transport Defect

    Intellectual disability Nystagmus Thrombocytopenia Reduced visual acuity Ptosis Dilatation Myopathy Myopia Sinusitis Sepsis Downslanted palpebral fissures Tics Nyctalopia Hepatomegaly[] […] serum uric acid levels. ( 27151312 ) Solak B....Solak Y. 2016 15 Relationship between acne vulgaris and attention-deficit/hyperactivity disorder symptoms in a clinical sample[] […] sinusitis Abnormality of the cerebral vasculature Thyroiditis Vitamin E deficiency Antinuclear antibody positivity Abnormality of the thyroid gland Prostatitis Macular atrophy Intermittent[]

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