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2,200 Possible Causes for Hepatomegaly, Jaundice

  • Infectious Mononucleosis

    We report a case of infectious mononucleosis in a 72-year old jaundiced gentleman with ferritin level of 2438 that normalised on clinical improvement.[ncbi.nlm.nih.gov] The patient showed severe hepatomegaly incidentally, and dual positivity of Immunoglobulin (Ig) M to Epstein-Barr virus (EBV) viral capsid antigen (VCA) and cytomegalovirus[ncbi.nlm.nih.gov] […] mononucleosis due to Epstein-Barr virus (EBV) infection sometimes causes acute hepatitis, which is usually self-limiting with mildly elevated transaminases, but rarely with jaundice[ncbi.nlm.nih.gov]

  • Malignant Neoplasm

    […] spread to other parts of the body then the following symptoms may be experienced by the individual: Low back pain or pain in the pelvis to bone metastasis Abdominal pain and jaundice[epainassist.com]

  • Neonatal Hepatitis

    The ACS described here is based on 5 clinical parameters--Age, Jaundice, Colour of urine and stool and Clinical examination of liver.[ncbi.nlm.nih.gov] The hepatitis group had the highest frequencies of high-grade hepatomegaly and splenomegaly. Fifty six cases completely recovered.[ncbi.nlm.nih.gov] The common symptoms include jaundice (yellow discoloration of the skin and the whites of the eyes) and hepatomegaly (liver enlargement).[biology-online.org]

  • Hepatitis A

    […] urine, jaundice , fever, abdominal pain[en.wikipedia.org] The hepatomegaly continues for another 2-12 weeks and thereafter the liver regains its normal function. Hepatitis A is best diagnosed serologically.[symptoma.com] Common examination findings are hepatomegaly and clinical jaundice with marked elevation of serum transaminases (usually 1000 units/L).[bestpractice.bmj.com]

  • Progressive Familial Intrahepatic Cholestasis

    Six patients who underwent PBD experienced short-term resolution of jaundice and pruritus.[ncbi.nlm.nih.gov] All four patients were presented with jaundice, pruritus, hepatomegaly, sleep disturbance. They fulfilled the criteria for PFIC. The surgery was uneventful.[ncbi.nlm.nih.gov] Clinical signs of cholestasis (discolored stools, dark urine) usually appear in the first months of life with recurrent or permanent jaundice associated with hepatomegaly[orpha.net]

  • Fascioliasis

    Patient may be asymptomatic or presents with jaundice and biliary colic or right hypochondriac pain due to bile duct obstruction with gastrointestinal symptoms.[ncbi.nlm.nih.gov] Because F. hepatica has a special tropism for the liver, abdominal pain, hepatomegaly, and constitutional symptoms are among the most common manifestations of acute-stage[ncbi.nlm.nih.gov] Computed tomography of the abdomen showed hepatomegaly (N 9), track-like hypodense lesions with subcapsular location (N 8), and subcapsular hematoma (N 2).[ncbi.nlm.nih.gov]

  • Congenital Toxoplasmosis

    Because biliary atresia can coexist with either congenital infection or inborn errors of metabolism, evaluation for an obstructive etiology of jaundice in infants with a recognized[ncbi.nlm.nih.gov] During the first month of life, physical examination was normal in 34.5%, and for those with clinical signs and symptoms, the main manifestations were hepatomegaly and/or[ncbi.nlm.nih.gov] Congenital toxoplasmosis may result in non-specific consequences like abortion, intra-uterine growth restriction, jaundice, hepatosplenomegaly or even intra-uterine death.[ncbi.nlm.nih.gov]

  • Hepatitis

    Common symptoms include jaundice, nausea, chills, rigors, diaphoresis, fatigue, and abdominal pain.[ncbi.nlm.nih.gov] Findings include: hepatomegaly 15.5 cm at the midclavicular line 4 possible decreased attenuation around the portal system and at the hepatic hilum (periportal oedema) possible[radiopaedia.org] Liver enzymes normalized within 2 weeks as well as jaundice.[ncbi.nlm.nih.gov]

  • Primary Sclerosing Cholangitis

    Primary sclerosing cholangitis (PSC) is a chronic inflammatory disease of bile ducts..Patients with PSC usually presents with fatigue, jaundice and pruritus.[ncbi.nlm.nih.gov] Liver disease other than PSC was defined as autoimmune hepatitis, hepatitis, hepatomegaly, liver failure, cirrhosis, portal hypertension, cholangiocarcinoma, or hepatobiliary[ncbi.nlm.nih.gov] A 48 year old lady presented with jaundice and exertional breathlesness.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    Although the severe obstructive jaundice requiring endoscopic therapy following cholecystectomy was complicated, critical intravascular hemolysis and thrombosis were not observed[ncbi.nlm.nih.gov] […] characterized by episodes of hemolytic anemia, hemoglobinuria (chiefly at night), pallor, icterus or bronzing of the skin, a moderate degree of splenomegaly, and sometimes hepatomegaly[medical-dictionary.thefreedictionary.com] The authors report a 57-year-old male patient who presented with diarrhea, darkened urine, jaundice and increased blood urea nitrogen and creatinine.[ncbi.nlm.nih.gov]

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