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4,418 Possible Causes for Hepatomegaly, Leg Ulcer, Scleromalacia Perforans

  • Diabetes Mellitus

    Abstract Glycogenic hepatopathy is a rare condition that causes significant hepatomegaly and elevated liver enzyme levels in uncontrolled type 1 diabetic patients.[ncbi.nlm.nih.gov] See Diabetic Foot, Leg Ulcers, Painful Foot. Frequent, recurrent and persistent infections.[patient.info] Children with diabetic dwarfism syndrome, which was also known as Mauriac's syndrome, suffered from stunted growth, hepatomegaly, and delayed puberty. 4 In 1936, the first[dx.doi.org]

    Missing: Scleromalacia Perforans
  • Sickle Cell Disease

    Hyperbaric Oxygen Therapy in the Treatment of Sickle Cell Leg Ulcers. J. Hyperbaric Med 1991; 6(1):1-4.[archive.rubicon-foundation.org] Additional autopsy findings included cardiomegaly with a heart weight of 450 gm (312 78), right atrial and right ventricular chamber dilatation, and hepatomegaly with a liver[ncbi.nlm.nih.gov] Hepatomegaly was seen in 28.6% of the subjects.[doi.org]

    Missing: Scleromalacia Perforans
  • Cooley's Anemia

    Abdominal imaging such as ultrasound scanning, MRI, or CT may show gallstones, liver cirrhosis, and hepatomegaly.[symptoma.com] Patients may have splenomegaly and bone deformities, recurrent leg ulcers, gallstones and infections.[myvmc.com] Common symptoms include pallor, jaundice, leg ulcers, gallstones (cholelithiasis), and abnormal enlargement of the liver and spleen.[rarediseases.org]

    Missing: Scleromalacia Perforans
  • Amyloidosis

    Hepatic involvement is common, but the clinical manifestations are usually mild with hepatomegaly and an elevated alkaline phosphatase level.[ncbi.nlm.nih.gov] […] that presents to a cancer care provider with nephrotic range proteinuria, heart failure with preserved ejection fraction, non-diabetic peripheral neuropathy, unexplained hepatomegaly[ncbi.nlm.nih.gov] […] disease produces hepatomegaly, but rarely jaundice.[patient.info]

    Missing: Scleromalacia Perforans
  • Polyarteritis Nodosa

    [Necrotic leg ulcers induced by vitamin K antagonists: five cases]. Ann Dermatol Venereol. 2011 Oct. 138(10):657-63. [Medline].[medscape.com] In June 2001, she was aware of edema and pain in both lower legs. At the same time, indurated erythemas and ulcers are seen on her lower legs.[ci.nii.ac.jp] Pain, erythemas and ulcers expanded, and she was admitted to our hospital in September, 2001. Lip biopsy revealed infiltration of lymphocytes in the salivary glands.[ci.nii.ac.jp]

    Missing: Scleromalacia Perforans
  • Porphyria Cutanea Tarda

    perforans.[nature.com] […] origin of the leg ulcerations in this young patient is not likely.[casesjournal.biomedcentral.com] Figure 1: Hyperpigmentation with blisters, ulceration, and erosions on legs Click here to view Figure 2: Scleroderma changes (atrophy) with scar on palm aspects of both the[ijhas.in]

  • Felty's Syndrome

    A 68-year-old woman with Felty's syndrome had massive hepatomegaly.[ncbi.nlm.nih.gov] This is a case report of a black woman with Felty's syndrome, who had recurrent, severe leg ulcers refractive to the usual treatment.[ncbi.nlm.nih.gov] An ultrasound scan is usually undertaken to assess splenomegaly and hepatomegaly.[gponline.com]

    Missing: Scleromalacia Perforans
  • Thalassemia

    Figure 1 Probability of OS by age and hepatomegaly. Figure 2 Probability of DFS by age and hepatomegaly.[doi.org] The latter are linked to a high prevalence of thromboembolic and cerebrovascular events, as well as leg ulcers and pulmonary hypertension.[ncbi.nlm.nih.gov] Untreated or poorly transfused patients show growth retardation, pallor, jaundice, poor musculature, genu valgum, leg ulcers, formation of masses due to extramedullary hematopoiesis[orpha.net]

    Missing: Scleromalacia Perforans
  • Chronic Right-Sided Congestive Heart Failure

    Right sided heart failure Right sided heart failure Right sided heart failure Right sided heart failure Anasarca (massive generalized body edema) Right sided heart failure Hepatomegaly[quizlet.com] We here report a case of Ebstein’s anomaly with refractory right-side heart failure and leg ulcers.[omicsonline.org] Abdominal examination elicited pain during superficial palpation on the right upper quadrant with hepatomegaly identification, with no signs of ascites.[austinpublishinggroup.com]

    Missing: Scleromalacia Perforans
  • Pyoderma Gangrenosum

    Corneal melting and scleromalacia perforans in a patient with pyoderma gangrenosum and acute myeloid leukemia. Ophthalmic Surg Lasers. 1998 Apr. 29(4):328-31. [Medline].[emedicine.com] What Are Leg Ulcers? Leg ulcers form when skin on your leg breaks open. These breaks or sores let air and bacteria travel into your skin’s tissue.[healthcare.utah.edu] Corneal melting and scleromalacia perforans in a patient with pyoderma gangrenosum and acute myeloid leukemia. Ophthalmic Surg Lasers . 1998 Apr. 29(4):328-31.[emedicine.medscape.com]

    Missing: Hepatomegaly

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