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2,645 Possible Causes for Hepatomegaly, Leukemia

  • Leukemia

    Five features were present in 50% of children: hepatomegaly (64%), splenomegaly (61%), pallor (54%), fever (53%) and bruising (52%).[ncbi.nlm.nih.gov] There are basically 4 types of leukemia, namely: Acute lymphocytic leukemia, acute myelogenous leukemia, chronic lymphocytic leukemia and chronic myeloid leukemia.[symptoma.com] Stage II Stage II CLL is characterized by absolute lymphocytosis with either hepatomegaly or splenomegaly with or without lymphadenopathy.[web.archive.org]

  • Primary Myelofibrosis

    The patient, a 62-year-old female, having had primary myelofibrosis for 13 years and a splenectomy 4 years before, was admitted because of high fever, hepatomegaly, thrombocythemia[ncbi.nlm.nih.gov] The molecular pathogenesis underlying the primary myelofibrosis (PMF) progression to acute myeloid leukemia (AML) is still not well defined.[ncbi.nlm.nih.gov] […] manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy, hepatomegaly[orpha.net]

  • Non-Hodgkin Lymphoma

    Hepatomegaly. Intermediate- and high-grade lymphomas: Most patients present with rapidly growing and bulky lymphadenopathy.[patient.info] Further studies are required to clarify the pathogenetic relationship between chronic myeloid leukemia and non-Hodgkin lymphomas.[ncbi.nlm.nih.gov] Slow growing or indolent lymphomas usually present with lymphadenopathy, hepatomegaly, splenomegaly or different types of cytopenias.[symptoma.com]

  • Myeloproliferative Disease

    Splenomegaly, hepatomegaly as well as fatigue, malaise or weight loss may appear in advanced stages.[orpha.net] There are two big categories of leukemias: acute leukemias and chronic leukemias.[pathologystudent.com] […] mice from two independent transgenic lines and from backcrosses into either the FVB or the C57BL/6 strains succumbed to a similar disease characterized by splenomegaly, hepatomegaly[ncbi.nlm.nih.gov]

  • Hemolytic Anemia

    Following this, a physical examination may reveal hepatomegaly or tenderness in the abdominal region.[symptoma.com] Autoimmune hemolytic anemia can occur in patients who have chronic lymphocytic leukemia (cll).[icd9data.com] H1N1 influenza–associated AIHA in children may respond to treatment with oseltamivir and intravenous immunoglobulin. [6] Fetal splenomegaly and associated hepatomegaly could[emedicine.com]

  • Paroxysmal Nocturnal Hemoglobinuria

    Pathological findings include systemic venous or portal thrombosis, normoblastic bone marrow hyperplasia, hepatomegaly with necrosis, hemosiderosis, and massive iron deposits[whonamedit.com] It may be associated with aplastic anemia, myelodysplastic syndrome, or acute myelogenous leukemia. Risk factors, except for prior aplastic anemia, are not known.[nlm.nih.gov] […] characterized by episodes of hemolytic anemia, hemoglobinuria (chiefly at night), pallor, icterus or bronzing of the skin, a moderate degree of splenomegaly, and sometimes hepatomegaly[medical-dictionary.thefreedictionary.com]

  • Chronic Myeloid Leukemia

    Hepatomegaly also occurs, although less commonly than splenomegaly. Hepatomegaly is usually part of the extramedullary hematopoiesis occurring in the spleen.[emedicine.medscape.com] What You Should Know Chronic myeloid leukemia (CML) is also called chronic myelogenous leukemia, chronic granulocytic leukemia and chronic myelocytic leukemia.[lls.org] Low-grade fever and excessive sweating Elevated white blood cell (WBC) count Splenomegaly Decreased appetite and food intake Left upper quadrant abdominal pain from splenomegaly Hepatomegaly[symptoma.com]

  • Familial Myelofibrosis

    In case of hepatomegaly, the liver extends to more than 3 cm below the right costal margin of the newborn.[symptoma.com] Cladribine This purine analogue, previously known as 2‐chlorodeoxyadenosine, has been shown to reduce clinically significant post‐splenectomy hepatomegaly and post‐splenectomy[onlinelibrary.wiley.com] […] abnormal cellular proliferation of megakaryocytes and granulocytes, increasing reticulin fibrosis progressing to collagen fibrosis and osteosclerosis May transform to acute leukemia[pathologyoutlines.com]

  • Polycythemia Vera

    […] neurological symptoms : dizziness, headache, visual disturbances, tinnitus Hypertension Splenomegaly : associated with early satiety and abdominal discomfort; less commonly hepatomegaly[amboss.com] A case with 17-year detailed illness history including evolution of polycythemia vera (PV) to myelofibrosis (MF) and then biphenotype acute leukemia (BAL) was reported.[ncbi.nlm.nih.gov] Symptoms of Budd-Chiari syndrome include pain in the upper right part of the abdomen, an abnormally enlarged liver (hepatomegaly), yellowing of the skin and the whites of[rarediseases.org]

  • Chronic Phase of Chronic Myeloid Leukemia

    Hepatomegaly. Enlarged lymph nodes are also a possibility. Anaemia can produce a hyperdynamic circulation. Easy bruising. Fever. Gout due to rapid cell turnover.[patient.info] Chronic myelogenous leukemia (CML) is a myeloproliferative disease also referred to as chronic myeloid leukemia.[symptoma.com] Poor-prognosis characteristics include the following clinical and laboratory factors: Older age Symptomatic presentation Poor performance status African-American descent Hepatomegaly[emedicine.medscape.com]

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