Create issue ticket

1,189 Possible Causes for Hepatomegaly, Leukopenia

  • Infectious Mononucleosis

    The patient showed severe hepatomegaly incidentally, and dual positivity of Immunoglobulin (Ig) M to Epstein-Barr virus (EBV) viral capsid antigen (VCA) and cytomegalovirus[ncbi.nlm.nih.gov] Leukopenia and thrombocytopenia are not uncommon.[ncbi.nlm.nih.gov] Although the complaints at admission did not differ between these two patient groups, the incidence of clinical signs (tonsillopharyngitis, lymphadenopathy, hepatomegaly,[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    […] characterized by episodes of hemolytic anemia, hemoglobinuria (chiefly at night), pallor, icterus or bronzing of the skin, a moderate degree of splenomegaly, and sometimes hepatomegaly[medical-dictionary.thefreedictionary.com] CBC showed leukopenia (WBC 2.9 x 103 /µL) with neutropenia (segmented neutrophils 48%), macrocytic anemia (Hgb 6.1 g/dL, hematocrit 20%, MCV,113 fL) and thrombocytopenia ([ncbi.nlm.nih.gov] Leukopenia, thrombocytopenia, arterial and venous thromboses, and episodic crises are common. Diagnosis requires flow cytometry.[merckmanuals.com]

  • Typhus

    The most common CT finding was hepatomegaly (74.4%), followed by splenomegaly (66.7%).[ncbi.nlm.nih.gov] Some of the common abnormalities noted include proteinuria, leukopenia, thrombocytopenia, higher levels of transaminase, and hypoalbuminemia.[symptoma.com] One enlarged lymph node in the right axilla and hepatomegaly were elicited. Weil-Felix reaction Ox-K was positive with 1:360 dilution.[ncbi.nlm.nih.gov]

  • Brucellosis

    Physical examination of the patient revealed massive hepatomegaly.[ncbi.nlm.nih.gov] Leukopenias associated with thrombocytopenia were observed. BMA showed to be normal.[ncbi.nlm.nih.gov] Brucellosis is a multisystem infection found worldwide that has a broad range of characteristics, which range from acute fever and hepatomegaly to chronic infections that[ncbi.nlm.nih.gov]

  • Malaria

    Patients with heavy hepatocyte load may present with hepatomegaly.[symptoma.com] Anemia, Leukopenia, and thrombocytopenia are commonly observed hematological abnormalities in malaria and typhoid patients.[ncbi.nlm.nih.gov] Enlargement of the liver (hepatomegaly) and spleen (splenomegaly) may be found during a physical examination.[betterhealth.vic.gov.au]

  • Primary Myelofibrosis

    The patient, a 62-year-old female, having had primary myelofibrosis for 13 years and a splenectomy 4 years before, was admitted because of high fever, hepatomegaly, thrombocythemia[ncbi.nlm.nih.gov] We found that fibrosis grade 2 and greater on a 0-3 scale was associated with clinical characteristics indicative of a more advanced disease, such as anemia, leukopenia, thrombocytopenia[ncbi.nlm.nih.gov] […] manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy, hepatomegaly[orpha.net]

  • Hairy Cell Leukemia

    Hepatomegaly and liver dysfunction may be found in 20% of patients.[symptoma.com] Later he developed leukopenia and pancytopenia. Bone marrow biopsies showed fibrosis.[ncbi.nlm.nih.gov] The HCL patients had a significantly higher frequency of leukopenia (p 0.024) and monocytopenia (p 0.008) and a lower frequency of leukocytosis (p 0.018) than HCL-v patients[ncbi.nlm.nih.gov]

  • Aggressive Systemic Mastocytosis

    However, loss of appetite due to hepatomegaly is not the only condition that causes ASM patients to lose weight: Mast cells also infiltrate the intestinal walls, which causes[symptoma.com] In fact, bone marrow failure is associated with cytopenias and patients suffering from anemia, leukopenia, or thrombocytopenia may present with pallor, weakness, and fatigue[symptoma.com] Hepatic and splenic mast cell infiltration cause palpable hepatomegaly and splenomegaly and may ensue loss of appetite, aszites, and portal hypertension as well as hypersplenism[symptoma.com]

  • Familial Myelofibrosis

    In case of hepatomegaly, the liver extends to more than 3 cm below the right costal margin of the newborn.[symptoma.com] Blood counts generally reveal normocytic, normochromic anemia, leukopenia, and thrombocytopenia.[symptoma.com] Thus, patients suffering from myelofibrosis eventually develop anemia, leukopenia, and thrombocytopenia.[symptoma.com]

  • Malignant Histiocytosis

    Most patients presented with systemic symptoms and lymphadenopathy (92%), splenomegaly (100%) and hepatomegaly (67%).[ncbi.nlm.nih.gov] Two years later, he manifested persistent fever, leukopenia, effusions and hypoproteinemia, and his general condition worsened progressively.[ncbi.nlm.nih.gov] Lymphadenopathy, splenomegaly, hepatomegaly, skin conditions such as rashes and multiple tumors, as well as gastrointestinal and other problems, are also encountered.[symptoma.com]

Further symptoms

Similar symptoms