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1,494 Possible Causes for Hepatomegaly, No Retinopathy

  • Diabetes Mellitus

    Abstract Glycogenic hepatopathy is a rare condition that causes significant hepatomegaly and elevated liver enzyme levels in uncontrolled type 1 diabetic patients.[ncbi.nlm.nih.gov] […] overall extent of retinopathy in both eyes.[doi.org] Children with diabetic dwarfism syndrome, which was also known as Mauriac's syndrome, suffered from stunted growth, hepatomegaly, and delayed puberty. 4 In 1936, the first[dx.doi.org]

  • Diabetes Mellitus Type 1

    Hepatomegaly and elevated liver enzymes in patients with diabetes are commonly associated with fatty liver disease.[ncbi.nlm.nih.gov] Author information 1 Dept of Ophthalmology, Academic Medical Center, Amsterdam, The Netherlands. h.w.vandijk@amc.nl Abstract Diabetic retinopathy (DR) classically presents[ncbi.nlm.nih.gov] In type 2 diabetes, PAD risk was associated with microalbuminuria (OR 2.1), macroalbuminuria (OR 3.3), background retinopathy (OR 1.9), proliferative retinopathy (OR 2.8),[ncbi.nlm.nih.gov]

  • Mauriac's Syndrome

    Mauriac's syndrome should be considered in subjects with brittle type 1 diabetes and hepatomegaly.[ncbi.nlm.nih.gov] We conclude that substantial elevation of serum IGF-1 may be another risk factor for the progression of mild diabetic retinopathy to the proliferative state.[ncbi.nlm.nih.gov] Paradoxically, with improved control, retinopathy progressed rapidly.[journals.lww.com]

  • Congenital Rubella Syndrome

    The infant may be small for gestational age and exhibit hyperbilirubinemia, thrombocytopenia, and hepatomegaly.[medical-dictionary.thefreedictionary.com] […] scar, uveitis may require treatment to preserve or restore vision Retinopathy rarely requires treatment and typically remains stationary[kellogg.umich.edu] ., isolated valve defects, pulmonary artery stenosis, ventricular septal defect, tetralogy of Fallot or patent ductus arteriosus Interstitial pneumonia Hepatitis, hepatomegaly[symptoma.com]

  • Cockayne Syndrome

    It also showed hepatomegaly and altered vertebral bodies. The ribs and clavicles were thinned with sclerosis at the margins.[elsevier.es] Other clinical findings were cataract, pigmentary retinopathy, and peripheral neuropathy. The onset of the disease was between 3 and 6 months of age.[ncbi.nlm.nih.gov] […] characterized by a variety of clinical features including cachectic dwarfism, severe neurological manifestations including microcephaly and cognitive deficits, pigmentary retinopathy[ncbi.nlm.nih.gov]

  • Long Chain Hydroxyacyl-CoA Dehydrogenase Deficiency

    Clinical considerations: Poor feeding, vomiting, lethargy Hypoglycemia Metabolic acidosis Hepatomegaly Cardiac insufficiency History of sudden unexpected death in a sibling[archildrens.org] […] hydroxyacyl-CoA dehydrogenase deficiency Symptoms and clinical features may include: 2 Clinical Features of Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency : Pigmentary retinopathy[familydiagnosis.com] An association between retinopathy and DHA deficiency has been demonstrated.[emedicine.medscape.com]

  • Sickle Cell Disease

    Additional autopsy findings included cardiomegaly with a heart weight of 450 gm (312 78), right atrial and right ventricular chamber dilatation, and hepatomegaly with a liver[ncbi.nlm.nih.gov] Proliferative sickle retinopathy Proliferative sickle retinopathy (PSR) is the most severe ocular change in SCD.[emedicine.com] Hepatomegaly was seen in 28.6% of the subjects.[doi.org]

  • Mitochondrial Trifunctional Protein Deficiency

    Patients with long-chain 3-hydroxyacyl coenzyme A dehydrogenase (LCHAD) deficiency manifest hypoketotic hypoglycemia, hepatomegaly, hypotonia, lactic acidemia, acute renal[ncbi.nlm.nih.gov] Mitochondrial trifunctional protein deficiency, a recently identified disorder of fatty-acid oxidation, may show characteristic features such as peripheral neuropathy, pigmentary retinopathy[ncbi.nlm.nih.gov] Finally, the overall examination is also notable for hepatomegaly and jaundice.[symptoma.com]

  • Toxoplasmosis

    […] common encephalomyelitis, retinochoroiditis, intracranial calcification and hydrocephalus to the non-specific symptoms of acute infection such as convulsion, splenomegaly, hepatomegaly[fao.org] Unilateral pigmentary retinopathy mimicking retinitis pigmentosa [37] Recurrence Recurrent lesions tend to occur at the margins of old scars, but they also can occur elsewhere[eyewiki.aao.org] There may be ventriculomegaly, CNS calcifications, placental changes, hepatomegaly, splenomegaly, ascites and pericardial or pleural effusion [ 3 ].[patient.info]

  • Hemochromatosis

    […] transferrin saturation (TS); ALT; AST; GGT; elevated C-reactive protein; ß-thalassemia; neutrophils; lymphocytes; monocytes; platelets; metacarpophalangeal joint hypertrophy; hepatomegaly[ncbi.nlm.nih.gov] The authors hypothesize that the retinopathy could be linked to hemochromatosis because of the pathophysiology of iron homeostasis and the toxicity of iron overload for the[ncbi.nlm.nih.gov] Eight of the 16 homozygous subjects had clinical findings that were consistent with the presence of hereditary hemochromatosis, such as hepatomegaly, skin pigmentation, and[ncbi.nlm.nih.gov]

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