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717 Possible Causes for Hepatomegaly, Pancytopenia

  • Pernicious Anemia

    Some people with Pernicious Anemia may have an abnormally enlarged liver (hepatomegaly) or spleen (splenomegaly).[rarediseases.org] The outcome was rapidly marked by febrile pancytopenia and ataxia leading to the diagnosis of pernicious anemia.[ncbi.nlm.nih.gov] Hepatomegaly and splenomegaly may be present.[patient.info]

  • Primary Myelofibrosis

    The patient, a 62-year-old female, having had primary myelofibrosis for 13 years and a splenectomy 4 years before, was admitted because of high fever, hepatomegaly, thrombocythemia[ncbi.nlm.nih.gov] This is then followed by pancytopenia (a reduction in the number of red and white blood cells, as well as platelets).[aoporphan.com] […] manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy, hepatomegaly[orpha.net]

  • Leukemia

    Five features were present in 50% of children: hepatomegaly (64%), splenomegaly (61%), pallor (54%), fever (53%) and bruising (52%).[ncbi.nlm.nih.gov] This fact sheet discusses the theory that intermittent fasting may reduce the risk of cancer or improve outcomes with anticancer treatments. more » A 47-Year-Old Woman with Pancytopenia[cancertherapyadvisor.com] Stage II Stage II CLL is characterized by absolute lymphocytosis with either hepatomegaly or splenomegaly with or without lymphadenopathy.[web.archive.org]

  • Paroxysmal Nocturnal Hemoglobinuria

    Pathological findings include systemic venous or portal thrombosis, normoblastic bone marrow hyperplasia, hepatomegaly with necrosis, hemosiderosis, and massive iron deposits[whonamedit.com] We report a 19-year-old female patient admitted to the hospital with pancytopenia. Workout of pancytopenia disclosed paroxysmal nocturnal hemoglobinuria.[ncbi.nlm.nih.gov] […] characterized by episodes of hemolytic anemia, hemoglobinuria (chiefly at night), pallor, icterus or bronzing of the skin, a moderate degree of splenomegaly, and sometimes hepatomegaly[medical-dictionary.thefreedictionary.com]

  • Familial Myelofibrosis

    In case of hepatomegaly, the liver extends to more than 3 cm below the right costal margin of the newborn.[symptoma.com] The illness presented with pallor, haemorrhagic symptoms, and hepatosplenomegaly, and the blood picture was that of pancytopenia and leucoerythroblastosis.[ncbi.nlm.nih.gov] Pancytopenia and leukoerythroblastosis require further clarification and should prompt a bone marrow biopsy.[symptoma.com]

  • Chronic Lymphocytic Leukemia

    Patients may sometimes present with hepatomegaly , splenomegaly or both and/or a hemolytic anemia .[radiopaedia.org] The symptoms of this infection range from a silent infection to fever, enlargement of the liver and spleen, weight loss, and pancytopenia.[ncbi.nlm.nih.gov] Brentuximab vedotin had a transient effect, but the patient died of sepsis due to residual PTCL and pancytopenia.[ncbi.nlm.nih.gov]

  • Myeloproliferative Disease

    […] mice from two independent transgenic lines and from backcrosses into either the FVB or the C57BL/6 strains succumbed to a similar disease characterized by splenomegaly, hepatomegaly[ncbi.nlm.nih.gov] Four years later, at the age of 16, her brother was diagnosed as having acute myelofibrosis, and some months afterwards he died from fulminant pneumonia coincidently with pancytopenia[ncbi.nlm.nih.gov] Splenomegaly, hepatomegaly as well as fatigue, malaise or weight loss may appear in advanced stages.[orpha.net]

  • Systemic Lupus Erythematosus

    Other signs are: Pancreatitis, Lupus Enteropathy, Hepatitis and Hepatomegaly 5. Systemic Fever, Malaise/Fatigue, Lymphadenopathy, Weight loss 6.[fidanoski.ca] Laboratory data revealed pancytopenia and immunological abnormalities.[ncbi.nlm.nih.gov] Evaluation revealed pancytopenia with normocellular marrow, hypocomplementaemia and Coomb's positive haemolytic anaemia.[ncbi.nlm.nih.gov]

  • Mantle Cell Lymphoma

    Characteristics at diagnosis involved lymphadenopathy (82%), splenomegaly (44%), B-symptoms (39%), and hepatomegaly (10%).[ncbi.nlm.nih.gov] Splenomegaly is often massive, while aberrant WBC count may be seen, either as markedly high leukocytosis or pancytopenia.[symptoma.com] Signs and symptoms of MCL may include fever, night sweats, enlarged lymph nodes, fatigue, splenomegaly ( enlarged spleen ), hepatomegaly ( enlarged liver ), and weight loss[rxlist.com]

  • Hairy Cell Leukemia

    No hepatomegaly or lymphadenopathy was detected.[ncbi.nlm.nih.gov] We should keep in mind other reasons for vasculitis such as lymphoproliferative disease, especially whose who have hematological abnormalities such as pancytopenia. 2014 Asia[ncbi.nlm.nih.gov] Hepatomegaly and liver dysfunction may be found in 20% of patients.[symptoma.com]

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