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1,279 Possible Causes for Hepatomegaly, Pancytopenia

  • Malignant Neoplasm

    After 15 months a diagnosis of urothelial carcinoma of the bladder was made; after a further 6 months pneumonitis and pancytopenia developed.[ncbi.nlm.nih.gov] She was discharged one month later in poor condition with the principal diagnosis of hemorrhage/ pancytopenia, and a secondary diagnosis of metastatic head and neck cancer[ncbi.nlm.nih.gov]

  • Niemann-Pick Disease

    Although neurodegeneration defines the disease's severity, in most patients it is preceded by hepatic complications such as cholestatic jaundice or hepatomegaly.[ncbi.nlm.nih.gov] Patients with type B NPD have minimal neurologic involvement but pancytopenia is common.[symptoma.com] He was first admitted to the hospital at 2 months because of vomiting, refusal to feed, lethargy, hepatomegaly and mild transaminasaemia.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    […] characterized by episodes of hemolytic anemia, hemoglobinuria (chiefly at night), pallor, icterus or bronzing of the skin, a moderate degree of splenomegaly, and sometimes hepatomegaly[medical-dictionary.thefreedictionary.com] We report a 19-year-old female patient admitted to the hospital with pancytopenia. Workout of pancytopenia disclosed paroxysmal nocturnal hemoglobinuria.[ncbi.nlm.nih.gov] The major causes of associated morbidity and mortality are chronic intravascular hemolysis, pancytopenia, and venous thrombosis.[ncbi.nlm.nih.gov]

  • Brucellosis

    Physical examination of the patient revealed massive hepatomegaly.[ncbi.nlm.nih.gov] Pancytopenia improved with treatment of brucellosis on all patients.[ncbi.nlm.nih.gov] Brucellosis is a multisystem infection found worldwide that has a broad range of characteristics, which range from acute fever and hepatomegaly to chronic infections that[ncbi.nlm.nih.gov]

  • Mantle Cell Lymphoma

    Characteristics at diagnosis involved lymphadenopathy (82%), splenomegaly (44%), B-symptoms (39%), and hepatomegaly (10%).[ncbi.nlm.nih.gov] Splenomegaly is often massive, while aberrant WBC count may be seen, either as markedly high leukocytosis or pancytopenia.[symptoma.com] Signs and symptoms of MCL may include fever , night sweats , enlarged lymph nodes , fatigue , splenomegaly ( enlarged spleen ), hepatomegaly ( enlarged liver ), and weight[rxlist.com]

  • Chronic Lymphocytic Leukemia

    […] of the left zygomatic region; anterior nasal bleeding; pustulous non-itching lesions at the cervical region and posterior thorax; enlarged bilateral axillary lymph nodes; hepatomegaly[ncbi.nlm.nih.gov] The symptoms of this infection range from a silent infection to fever, enlargement of the liver and spleen, weight loss, and pancytopenia.[ncbi.nlm.nih.gov] Stage II: Lymphocytosis along with either splenomegaly or hepatomegaly is present. Lymphadenopathy may or may not be present.[symptoma.com]

  • Visceral Leishmaniasis

    The features of VL may be different in immunosuppressed patients, with more fever and less hepatomegaly and leukopenia than in HIV-infected patients.[ncbi.nlm.nih.gov] We present an unusual case of febrile pancytopenia in a nonagenarian who was diagnosed with visceral leishmaniasis.[ncbi.nlm.nih.gov] […] was admitted to Imam Reza teaching hospital in Mashhad, Iran in 2010 with fever, sweating, abdominal distention, massive hematemesis, weight loss, huge splenomegaly and hepatomegaly[ncbi.nlm.nih.gov]

  • Aggressive Systemic Mastocytosis

    However, loss of appetite due to hepatomegaly is not the only condition that causes ASM patients to lose weight: Mast cells also infiltrate the intestinal walls, which causes[symptoma.com] […] organomegaly and organ dysfunction, impairment of hematopoietic function (which may result in disruption of the blood count ranging from isolated cytopenia to more or less marked pancytopenia[orpha.net] Hepatic and splenic mast cell infiltration cause palpable hepatomegaly and splenomegaly and may ensue loss of appetite, aszites, and portal hypertension as well as hypersplenism[symptoma.com]

  • Leukemia

    […] tiredness and fatigue Pain in bone Fever accompanied by chills Excessive sweating especially during night hours Easy prone to infections Bleeding or bruising very easily Hepatomegaly[symptoma.com] Bone marrow examination Histochemical studies, cytogenetics, immunophenotyping, and molecular biology studies Imaging CBC and peripheral smear are the first tests done; pancytopenia[merckmanuals.com] […] patient has enlarged lymph nodes Splenomegaly, which is an enlarged spleen Anemia, meaning low levels of red blood cells Thrombocytopenia, meaning low levels of platelets Hepatomegaly[cancer.net]

  • Primary Myelofibrosis

    The patient, a 62-year-old female, having had primary myelofibrosis for 13 years and a splenectomy 4 years before, was admitted because of high fever, hepatomegaly, thrombocythemia[ncbi.nlm.nih.gov] Primary myelofibrosis is a unique entity among BCR-ABL-negative myeloproliferative diseases, manifesting as bone marrow fibrosis and pancytopenia.[ncbi.nlm.nih.gov] […] manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy, hepatomegaly[orpha.net]

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