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311 Possible Causes for Hepatomegaly, Periorbital Edema

  • Infectious Mononucleosis

    The patient showed severe hepatomegaly incidentally, and dual positivity of Immunoglobulin (Ig) M to Epstein-Barr virus (EBV) viral capsid antigen (VCA) and cytomegalovirus[ncbi.nlm.nih.gov] edema, and lymphadenopathy (which often involves the posterior cervical chain). 2 It may also be associated with hepatomegaly and splenomegaly.[journals.lww.com] Although the complaints at admission did not differ between these two patient groups, the incidence of clinical signs (tonsillopharyngitis, lymphadenopathy, hepatomegaly,[ncbi.nlm.nih.gov]

  • Trichinellosis

    Typical clinical features of Trichinella infection such as periorbital edema and severe myalgia were either minimal or absent.[ncbi.nlm.nih.gov] Hepatomegaly was noticed in 34.4% of cases, hypoalbuminemia in 40.6%, and hypoproteinemia in 34.4%.[ncbi.nlm.nih.gov] We hereby discuss an atypical case of trichinellosis, which presented with myositis of the thigh muscles but had no eosinophilia and no facial or periorbital edema and was[ncbi.nlm.nih.gov]

  • Tularemia

    […] typhoidal nausea vomiting Physical exam high fever ulceroglandular tender maculopapular rash initially lesion may ulcerate with a raised border tender lymphadenopathy typhoidal hepatomegaly[medbullets.com] In addition, involvement of larynx, oropharynx, and retropharynx; presence of periorbital edema; and neck abscess formation were evaluated using CECT.[ncbi.nlm.nih.gov] In the oculoglandular form, fever, lymphadenopathy, periorbital edema, conjunctival injection, and chemosis were found.[ncbi.nlm.nih.gov]

  • Congestive Heart Failure

    Cardiac examination at the age of 6 years revealed constrictive pericarditis with significant elevation of atrial filling pressures, consecutive hepatomegaly, and protein[ncbi.nlm.nih.gov] Right upper quadrant sonogram revealed hepatomegaly of 15 cm, trace amount of perihepatic ascites, pericholecystic fluid, and also thickened edematous gallbladder wall with[ncbi.nlm.nih.gov] On examination, the findings include raised jugular pressure and positive hepatojugular reflex, tender hepatomegaly and features of heart disease.[symptoma.com]

  • Adult-Onset Still Disease

    RHS can be considered when an AOSD patient shows at least 2 of the following 3 findings: low platelet count, anemia, and hepatomegaly.[ncbi.nlm.nih.gov] Periorbital edema/erythema and nonlinear urticarial lesions were also seen.[ncbi.nlm.nih.gov] Liver involvement was observed in all cases, with hepatomegaly in 81.3%, increased liver enzymes in 50.0%, and hypergammaglobulinemia in 68.8%.[ncbi.nlm.nih.gov]

  • Chagas Disease

    […] local lymphadenopathy and fever over several weeks More general symptoms include: headache pallor myalgia dyspnoea oedema in inferior limbs or face abdominal pain cough hepatomegaly[gov.uk] Symptoms after a Triatominae bite typically begin with a skin lesion or unilateral periorbital edema, then progress to fever, malaise, generalized lymphadenopathy, and hepatosplenomegaly[merckmanuals.com]

  • Liver Cirrhosis

    Cardinal symptoms include fasting hypoglycemia, lactic acidosis and hepatomegaly as well as neutropenia.[ncbi.nlm.nih.gov] Liver enlargement is usually an indicator of liver disease, although there are usually no symptoms associated with a slightly enlarged liver (hepatomegaly).[stanfordchildrens.org] Patients may be asymptomatic or have fatigue, pruritus , and non-jaundice skin hyperpigmentation with hepatomegaly.[en.wikipedia.org]

  • Lipodystrophy

    Severe dyslipideaemia, hepatomegaly and non-alcoholic steatoheaptitis are almost always noted.[dnatesting.uchicago.edu] Children can also develop periorbital edema (swelling around the eye sockets), and edema (clubbing) of finger and/or toes, and gradual enlargement of the liver, along with[autoinflammatory.org] An enlarged liver (hepatomegaly) is also common. Hepatomegaly is caused by the accumulation of fat in the liver (fatty liver or steatosis).[rarediseases.org]

  • Hodgkin's Disease

    The presenting feature common in all cases was superficial lymphadenopathy followed by hepatomegaly in 17 (20%) cases and splenomegaly in 16 (19%).[ncbi.nlm.nih.gov] Abdomen: Abdominal enlargement may be noted with splenomegaly or hepatomegaly.[symptoma.com] The nodes may also feel rubbery and swollen when examined Splenomegaly: enlargement of the spleen occurs in about 30% of people with Hodgkin's lymphoma Hepatomegaly: enlargement[slideshare.net]

  • Chronic Myeloid Leukemia

    Cutaneous hyperpigmentation and periorbital edema are common long-term adverse effects of imatinib in Indian patients.[ncbi.nlm.nih.gov] Low-grade fever and excessive sweating Elevated white blood cell (WBC) count Splenomegaly Decreased appetite and food intake Left upper quadrant abdominal pain from splenomegaly Hepatomegaly[symptoma.com] Hepatomegaly also occurs, although less commonly than splenomegaly. Hepatomegaly is usually part of the extramedullary hematopoiesis occurring in the spleen.[emedicine.medscape.com]

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