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620 Possible Causes for Hepatomegaly, Petechiae

  • Infectious Mononucleosis

    The patient showed severe hepatomegaly incidentally, and dual positivity of Immunoglobulin (Ig) M to Epstein-Barr virus (EBV) viral capsid antigen (VCA) and cytomegalovirus[ncbi.nlm.nih.gov] Conclusions and Relevance In adolescent and adult patients presenting with sore throat, the presence of posterior cervical, inguinal or axillary adenopathy, palatine petechiae[doi.org] […] splenomegaly possible splenic rupture splenic infarction has been reported 3 generalized lymphadenopathy, including cervical lymphadenopathy tonsillar enlargement possible hepatomegaly[radiopaedia.org]

  • Leukemia

    Five features were present in 50% of children: hepatomegaly (64%), splenomegaly (61%), pallor (54%), fever (53%) and bruising (52%).[ncbi.nlm.nih.gov] These were petechiae/purpura (category derived from ‘petechiae’, ‘purpura’ and ‘petechiae/purpura’), mucosal bleeding (including ‘mucosal bleeding’ and ‘bleeding gums’), anorexia[doi.org] Stage II Stage II CLL is characterized by absolute lymphocytosis with either hepatomegaly or splenomegaly with or without lymphadenopathy.[web.archive.org]

  • Childhood Acute Lymphoblastic Leukemia

    RESULTS: Among 130 children receiving PEG-asparaginase biweekly, 29 developed SOS ( 2 criteria: hyperbilirubinemia, hepatomegaly, ascites, weight gain 2.5%, unexplained thrombocytopenia[ncbi.nlm.nih.gov] Thrombocytopenia manifests itself as bleeding, bruising and, in severe cases, petechiae.[symptoma.com] Hepatomegaly and/or splenomegaly due to leukemic infiltration are present in many patients at diagnosis but are often overlooked.[clinicaladvisor.com]

  • Primary Myelofibrosis

    The patient, a 62-year-old female, having had primary myelofibrosis for 13 years and a splenectomy 4 years before, was admitted because of high fever, hepatomegaly, thrombocythemia[ncbi.nlm.nih.gov] Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy[orpha.net] Petechiae (flat, red, pinpoint spots under the skin that are caused by bleeding). Fever. Night sweats. Weight loss.[navigatingcare.com]

  • Pernicious Anemia

    Some people with Pernicious Anemia may have an abnormally enlarged liver (hepatomegaly) or spleen (splenomegaly).[rarediseases.org] Petechiae in the mammillary bodies. WKS, acute lesion. Periaqueductal lesions. WKS, acute lesion. Periaqueductal lesions. WKS, burned out lesion. WKS, burned out lesion.[neuropathology-web.org] Hepatomegaly and splenomegaly may be present.[patient.info]

  • Chronic Lymphocytic Leukemia

    […] of the left zygomatic region; anterior nasal bleeding; pustulous non-itching lesions at the cervical region and posterior thorax; enlarged bilateral axillary lymph nodes; hepatomegaly[ncbi.nlm.nih.gov] The most common treatment-related AEs (reported in at least 5 percent of patients) were headache (20 percent), an increased tendency to bruise (12 percent) and petechiae ([curetoday.com] Patients may sometimes present with hepatomegaly , splenomegaly or both and/or a hemolytic anemia .[radiopaedia.org]

  • Myeloproliferative Disease

    […] mice from two independent transgenic lines and from backcrosses into either the FVB or the C57BL/6 strains succumbed to a similar disease characterized by splenomegaly, hepatomegaly[ncbi.nlm.nih.gov] […] of splenic infarction and perisplenitis Clinical symptoms can include the following: Pallor (except in patients with polycythemia vera) Plethora secondary to polycythemia Petechiae[emedicine.com] Splenomegaly, hepatomegaly as well as fatigue, malaise or weight loss may appear in advanced stages.[orpha.net]

  • Acute Myelocytic Leukemia

    Multivariate analysis showed that grades 1 or 2 GVHD (P .008) and no hepatomegaly at diagnosis (P .014) were associated with improved relapse-free survival (RFS).[ncbi.nlm.nih.gov] Thrombocytopenia often causes petechiae on the lower limbs. DIC may aggravate the situation and cause larger lesions.[patient.info] […] infection because there are a decreased number of healthy white blood cells , known as neutropenia Bruising or bleeding from decreased platelets, known as thrombocytopenia Petechiae[curesearch.org]

  • Amyloidosis

    Hepatic involvement is common, but the clinical manifestations are usually mild with hepatomegaly and an elevated alkaline phosphatase level.[ncbi.nlm.nih.gov] Although rare, cutaneous manifestations may be the first clinical sign of the disease and usually present as hemorrhagic lesions, such as purpura, petechiae, and ecchymosis[ncbi.nlm.nih.gov] […] that presents to a cancer care provider with nephrotic range proteinuria, heart failure with preserved ejection fraction, non-diabetic peripheral neuropathy, unexplained hepatomegaly[ncbi.nlm.nih.gov]

  • Chronic Myeloid Leukemia

    Low-grade fever and excessive sweating Elevated white blood cell (WBC) count Splenomegaly Decreased appetite and food intake Left upper quadrant abdominal pain from splenomegaly Hepatomegaly[symptoma.com] […] include: Bruising Excessive sweating (night sweats) Fatigue Fever Pressure under the lower left ribs from a swollen spleen Rash -- small pinpoint red marks on the skin ( petechiae[medlineplus.gov] Hepatomegaly also occurs, although less commonly than splenomegaly. Hepatomegaly is usually part of the extramedullary hematopoiesis occurring in the spleen.[emedicine.medscape.com]

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