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1,107 Possible Causes for Hepatomegaly, Portal Hypertension

  • Alcoholic Liver Disease

    This diagnosis was based on marked hepatomegaly, caudate lobe hypertrophy and failure to visualize hepatic veins by Doppler-ultrasound examination.[ncbi.nlm.nih.gov] Its blood level predicts portal hypertension and long-term mortality in AC patients.[ncbi.nlm.nih.gov] Initial stages of ALD may be asymptomatic apart from hepatomegaly and slightly elevated liver function tests.[symptoma.com]

  • Gaucher Disease

    hypertension.[ncbi.nlm.nih.gov] After 4years of ERT, therapeutic goals for thrombocytopenia and splenomegaly had been achieved in 100% of patients; goals for anemia and hepatomegaly had been achieved in[ncbi.nlm.nih.gov] Hematologic changes, bone pain, hepatomegaly, splenomegaly, and fatigue were the most recurrent signs and symptoms.[ncbi.nlm.nih.gov]

  • Schistosomiasis Japonica

    Hepatomegaly was found in 76.3% (1082/1419); hepatic fibrosis was found in 73.3% (1040/1419); and splenomegaly was found in 18.6% (264/1419).[ncbi.nlm.nih.gov] […] of various portal hypertensive dis orders, has clearly been achieved by these excellent contributions.[books.google.de] We discuss the role of sICAM-1 and TNFR-I and -II as candidate markers for schistosome-induced hepatomegaly and fibrosis, and their potential for assessing disease stage and[ncbi.nlm.nih.gov]

  • Progressive Familial Intrahepatic Cholestasis

    All four patients were presented with jaundice, pruritus, hepatomegaly, sleep disturbance. They fulfilled the criteria for PFIC. The surgery was uneventful.[ncbi.nlm.nih.gov] Gastrointestinal bleeding due to portal hypertension might be the presenting symptom in adolescents or young adults.[orpha.net] Clinical signs of cholestasis (discolored stools, dark urine) usually appear in the first months of life with recurrent or permanent jaundice associated with hepatomegaly[orpha.net]

  • Hepatic Sarcoidosis

    Clinical presentation was with weight loss, hepatomegaly and abnormal liver function tests.[ncbi.nlm.nih.gov] In most of the other patients, portal hypertension was the predominant and often the presenting symptom of hepatic sarcoidosis; in these patients portal hypertension was due[ncbi.nlm.nih.gov] Hepatomegaly was observed in all patients as well as abnormal serum liver function test reflected by anicteric cholestasis.[ncbi.nlm.nih.gov]

  • Hepatic Veno-Occlusive Disease

    […] veno-occlusive disease (VOD) , also known as sinusoidal obstruction syndrome (SOS) , is a condition arising from occlusion of hepatic venules. right upper quadrant pain painful hepatomegaly[radiopaedia.org] The congestion also causes increased pressure in the portal vein ( portal hypertension ).[msdmanuals.com] The presence of reversed flow in portal vein, increased peak systolic velocity of hepatic artery, monophasicity of hepatic vein, hepatomegaly, gallbladder wall thickness,[ncbi.nlm.nih.gov]

  • Congenital Hepatic Fibrosis

    The age at presentation ranged from 1.8-14 years (mean: 7.5 years); clinical manifestations at diagnosis were splenomegaly (12), hepatomegaly (11), failure to thrive (10),[ncbi.nlm.nih.gov] Abstract CONGENITAL hepatic fibrosis is a rare but important cause of portal hypertension in children; 1–6 it is even more rare as a cause of portal hypertension in adults[mdedge.com] Hepatomegaly was present in all patients and splenomegaly in all but one.[ncbi.nlm.nih.gov]

  • Aggressive Systemic Mastocytosis

    Hepatic and splenic mast cell infiltration cause palpable hepatomegaly and splenomegaly and may ensue loss of appetite, aszites, and portal hypertension as well as hypersplenism[symptoma.com] However, loss of appetite due to hepatomegaly is not the only condition that causes ASM patients to lose weight: Mast cells also infiltrate the intestinal walls, which causes[symptoma.com] hypertension or ascites Palpable splenomegaly is detected and is associated with hypersplenism Patients suffer pathological fractures or diagnostic imaging reveals large[symptoma.com]

  • Alcoholic Hepatitis

    In AH patients, ductular cell expansion correlated with portal hypertension and collagen expression.[ncbi.nlm.nih.gov] Jaundice was present in all patients with fever and tender hepatomegaly also being common.[ncbi.nlm.nih.gov] AH is characterized by an abrupt development of jaundice and complications related to liver insufficiency and portal hypertension in patients with heavy alcohol intake.[ncbi.nlm.nih.gov]

  • Primary Sclerosing Cholangitis

    Liver disease other than PSC was defined as autoimmune hepatitis, hepatitis, hepatomegaly, liver failure, cirrhosis, portal hypertension, cholangiocarcinoma, or hepatobiliary[ncbi.nlm.nih.gov] Patients with thrombocytopenia may have esophageal or gastric varices secondary to portal hypertension, leading to variceal bleeding which exposes the liver to further damage[ncbi.nlm.nih.gov] Primary Sclerosing Cholangitis (PSC) is characterized by progressive inflammatory fibrotic destruction of the biliary ducts and patients with PSC often have chronic jaundice, hepatomegaly[sancilio.com]

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