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2,003 Possible Causes for Hepatomegaly, Splenomegaly

  • Infectious Mononucleosis

    The patient showed severe hepatomegaly incidentally, and dual positivity of Immunoglobulin (Ig) M to Epstein-Barr virus (EBV) viral capsid antigen (VCA) and cytomegalovirus[ncbi.nlm.nih.gov] Clinical estimates of splenomegaly are fallible.[ncbi.nlm.nih.gov] Although the complaints at admission did not differ between these two patient groups, the incidence of clinical signs (tonsillopharyngitis, lymphadenopathy, hepatomegaly,[ncbi.nlm.nih.gov]

  • Malignant Neoplasm

    Following improvements in therapy for childhood malignancies, the striking increase in survival rate over the past 30 years has led to the increase risk of developing second malignant neoplasms (SMNs). We report a case of colorectal carcinoma as a SMN, following treatment for rhabdomyosarcoma. The patient was[…][ncbi.nlm.nih.gov]

  • Gaucher Disease

    After 4years of ERT, therapeutic goals for thrombocytopenia and splenomegaly had been achieved in 100% of patients; goals for anemia and hepatomegaly had been achieved in[ncbi.nlm.nih.gov] HALS for GD patients with refractory hypersplenism and massive splenomegaly is safe and feasible in experienced hands.[ncbi.nlm.nih.gov] Hematologic changes, bone pain, hepatomegaly, splenomegaly, and fatigue were the most recurrent signs and symptoms.[ncbi.nlm.nih.gov]

  • Niemann-Pick Disease

    Although neurodegeneration defines the disease's severity, in most patients it is preceded by hepatic complications such as cholestatic jaundice or hepatomegaly.[ncbi.nlm.nih.gov] Common disease-related morbidities included splenomegaly (96.6%), hepatomegaly (91.4%), liver dysfunction (82.6%), and pulmonary disease (75.0%).[ncbi.nlm.nih.gov] He was first admitted to the hospital at 2 months because of vomiting, refusal to feed, lethargy, hepatomegaly and mild transaminasaemia.[ncbi.nlm.nih.gov]

  • Brucellosis

    Physical examination of the patient revealed massive hepatomegaly.[ncbi.nlm.nih.gov] The most frequent admission symptoms and findings of the patients with pancytopenia were fever (75%), fatigue (50%), splenomegaly (75%), and hepatomegaly (41%).[ncbi.nlm.nih.gov] Brucellosis is a multisystem infection found worldwide that has a broad range of characteristics, which range from acute fever and hepatomegaly to chronic infections that[ncbi.nlm.nih.gov]

  • Malaria

    Patients with heavy hepatocyte load may present with hepatomegaly.[symptoma.com] We report the case of a 12-year-old child who was admitted to our Department, with 7 days' history of high fever and splenomegaly.[ncbi.nlm.nih.gov] Enlargement of the liver (hepatomegaly) and spleen (splenomegaly) may be found during a physical examination.[betterhealth.vic.gov.au]

  • Amyloidosis

    […] toenails Purple color on the eyelids, around the eyes (periorbital purpura), and/or other areas of skin folds Signs indicating the liver is affected include: Enlarged liver (hepatomegaly[my.clevelandclinic.org] We reported two cases with ApoA-1 amyloidosis, a 64-year-old man suffering from nephrotic syndrome and a 40-year-old man with nephrotic syndrome and splenomegaly.[ncbi.nlm.nih.gov] […] disease produces hepatomegaly, but rarely jaundice.[patient.info]

  • Plasma Cell Leukemia

    Primary Plasma cell leukaemia is more characterised by an extra medullar involvement such as hepatomegaly, splenomegaly, lymphadenopathy, lepto-meningeal infiltration or extramedullary[ncbi.nlm.nih.gov] Enlarged lymph nodes in axillary, pectoral, paratracheal, and periportal regions as well as slight hepatomegaly and splenomegaly were confirmed.[ncbi.nlm.nih.gov] Presenting signs and symptoms are similar to those seen in MM such as renal insufficiency, hypercalcemia, lytic bone lesions, anemia, and thrombocytopenia, but can also include hepatomegaly[ncbi.nlm.nih.gov]

  • Schistosomiasis Japonica

    Hepatomegaly was found in 76.3% (1082/1419); hepatic fibrosis was found in 73.3% (1040/1419); and splenomegaly was found in 18.6% (264/1419).[ncbi.nlm.nih.gov] Univariate and multivariate analysis in the discovery, replicative and combined studies, suggested that durations (years), splenomegaly, serum ALB and rs10118570 were independent[ncbi.nlm.nih.gov] […] reached clinical cure and 5152 (88.4 %) cases' condition having improved, which can be partially reflected in the significant decline of the proportion of hepatomegaly (splenomegaly[ncbi.nlm.nih.gov]

  • Mantle Cell Lymphoma

    Characteristics at diagnosis involved lymphadenopathy (82%), splenomegaly (44%), B-symptoms (39%), and hepatomegaly (10%).[ncbi.nlm.nih.gov] Fatigue, generalized lymphadenopathy and splenomegaly are its typical features.[symptoma.com] Signs and symptoms of MCL may include fever , night sweats , enlarged lymph nodes , fatigue , splenomegaly ( enlarged spleen ), hepatomegaly ( enlarged liver ), and weight[rxlist.com]

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