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311 Possible Causes for Hepatosplenomegaly, Hypercellular Bone Marrow

  • Leukemia

    […] fever, night sweats (unintentional) loss of weight fatigue syndrome (extreme weakness) swollen or bleeding gums nosebleed ( Epistaxis ) Enlargment of liver and spleen ( Hepatosplenomegaly[flexikon.doccheck.com] Bone marrow aspirate showed hypercellularity with increased myelopoiesis and markedly suppressed megakaryopoiesis giving an impression of acute myeloid leukemia and was confirmed[ncbi.nlm.nih.gov] Another important feature of bone marrow samples is its cellularity. Normal bone marrow contains hematopoietic (blood-forming) cells and fat cells.[web.archive.org]

  • Myeloproliferative Disease

    Marked myeloid proliferation, anemia, thrombocytopenia and hepatosplenomegaly were present; leukocyte alkaline phosphatase and fetal hemoglobin were moderately elevated.[ncbi.nlm.nih.gov] The chronic myeloproliferative diseases are characterized by relatively effective hematopoiesis, which results in a hypercellular bone marrow and elevation of one or more[clinlabnavigator.com] […] yes; there is effective maturation leading to increased peripheral blood counts Hepatosplenomegaly is common due to extramedullary hematopoiesis What is the spent phase found[quizlet.com]

  • Autoimmune Hemolytic Anemia

    A 7-month-old boy, presented with prolonged fever, erythematous rash, severe pallor and hepatosplenomegaly.[ncbi.nlm.nih.gov] Subsequently, the patient underwent a bone marrow biopsy that showed a hypercellular marrow with erythroid hyperplasia, but no evidence of dysplasia or lymphoma.[jmedicalcasereports.com] Computed tomography (CT) of the chest, abdomen and pelvis was remarkable for hepatosplenomegaly.[jmedicalcasereports.com]

  • Chronic Myeloid Leukemia

    Due to presenting complaint of bleeding diathesis and absence of hepatosplenomegaly, the case was undiagnosed for CML until the patient reported to us.[ncbi.nlm.nih.gov] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] A 59-year-old female with dry cough, referred to our hospital, exhibited hepatosplenomegaly, high basophil count, and high platelet count at admission without any other known[ncbi.nlm.nih.gov]

  • Polycythemia Vera

    Physical examination reveals multiple bruises on the bilateral upper and lower extremities and hepatosplenomegaly.[step1.medbullets.com] bone marrow 5.[slideshare.net] CNL is a rare myeloproliferative disorder characterized by a persistent increase of mature peripheral neutrophils, myeloid hyperplasia in bone marrow, hepatosplenomegaly,[kjim.org]

  • Chronic Phase of Chronic Myeloid Leukemia

    […] blasts plus promyelocytes in the peripheral blood and bone marrow and a platelet count of 100 10 9 per liter or more, with an absence of extramedullary disease except for hepatosplenomegaly[nejm.org] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] It can also present with symptoms indicative of hepatosplenomegaly and the resulting upper quadrant pain this causes.[en.wikipedia.org]

  • Acute Leukemia

    Physical examination showed jaundice, hepatosplenomegaly, and peripheral facial nerve palsy in addition to dermal nodules.[ncbi.nlm.nih.gov] ALL : Hypercellular bone marrow Numerous tightly packed lymphoblasts with undetectable cytoplasm, round, irregular, cleaved nuclei, dispersed chromatin, small nucleoli B[pathologyoutlines.com] Symptoms include anemia, fatigue, weight loss, easy bruising, thrombocytopenia, granulocytopenia with bacterial infections, bone pain, lymphadenopathy, hepatosplenomegaly,[medical-dictionary.thefreedictionary.com]

  • Cooley's Anemia

    Karimi M et al Prevalence of hepatosplenomegaly in beta thalassemia minor subjects in Iran. Eur J Radiol. 2007. doi: 10.1016/j.ejrad.2007.09.027 Google Scholar 8.[link.springer.com] Hepatosplenomegaly is a classic feature of beta thalassemia major. Untreated, beta thalassemia major may lead to heart failure and death.[symptoma.com] […] homozygous form of β-thalassemia, in which hemoglobin A is completely absent; it appears in the newborn period and is marked by hemolytic, hypochromic, microcytic anemia; hepatosplenomegaly[medical-dictionary.thefreedictionary.com]

  • Ayerza Syndrome

    Ayerza syndrome is named after Abel Ayerza and encompasses the clinical features of pulmonary hypertension. It is a progressive disease with mixed etiology, characterized by increased resistance in the pulmonary blood vessels. Ayerza syndrome (AS) describes the signs of pulmonary (arterial) hypertension. It is[…][symptoma.com]

  • Chronic Neutrophilic Leukemia

    Physical examination on admission revealed moderate hepatosplenomegaly.[ncbi.nlm.nih.gov] bone marrow with predominant neutrophilic granulopoiesis (M:E is 20:1 or more), the number of myeloblasts and promyelocytes is not increased, myelocytes and mature neutrophils[atlases.muni.cz] The most common clinical finding is hepatosplenomegaly. Pruritus, gout, and mucocutaneous bleeding are occasionally seen. The cause of CNL is currently unknown.[en.wikipedia.org]

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