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961 Possible Causes for Hepatosplenomegaly, Jaundice, Pallor

  • Tuberculosis

    A 50 year male presented with acute onset jaundice, significant weight loss and elevated liver enzymes with clinico-radiological suspicion of cholangiocarcinoma.[ncbi.nlm.nih.gov] He had mild pallor with mild hepatosplenomegaly. He had high inflammatory markers with pancytopenia in a peripheral blood smear.[ncbi.nlm.nih.gov] Tell your doctor or health care worker if you have unexplained illness or any of the following symptoms happen: nausea and/or vomiting jaundice - yellow skin or eyes, dark[nt.gov.au]

  • Malaria

    A 5-year-old immunocompetent girl presented with fever, jaundice, hepatosplenomegaly and pancytopenia.[ncbi.nlm.nih.gov] Infant presented with pallor, jaundice and massive spleen. Laboratory tests revealed anaemia, thrombocytopenia and bilirubinemia.[ncbi.nlm.nih.gov] Common physical findings include jaundice, hepatosplenomagaly and pallor.[clinicaladvisor.com]

  • Thalassemia

    Clinical description Patients present with moderate to severe anemia, jaundice and splenomegaly.[orpha.net] They have severe anemia and hepatosplenomegaly. Untreated children have severe failure to thrive and shortened life expectancy.[meddean.luc.edu] Clinical description Onset is during infancy with severe anemia, failure to thrive and progressive pallor.[orpha.net]

  • Babesiosis

    Jaundice, hepatosplenomegaly, anemia and conjugated hyperbilirubinemia developed in this preterm infant.[ncbi.nlm.nih.gov] Physical examination may reveal fever, splenomegaly, hepatomegaly, and pallor or jaundice. The diagnosis is confirmed with laboratory testing (see below).[clinicaladvisor.com] During hospitalization, the patient developed pancytopenia and jaundice and became progressively more ill.[ncbi.nlm.nih.gov]

  • Pharyngitis

    It affects the liver and spleen, and may lead to jaundice. Other viral infections that can result in pharyngitis include influenza (flu), measles, chickenpox and herpes.[health24.com] Presence of hepatosplenomegaly or lymphadenopathy outside the cervical region should raise suspicions regarding an underlying malignancy.[ncbi.nlm.nih.gov] , lethargy, malaise, weakness,Pallor, lethargy, malaise, weakness, anorexia, headache and dull back painanorexia, headache and dull back pain – Fever not prominentFever not[de.slideshare.net]

  • T-cell Acute Lymphoblastic Leukemia

    Obstructive jaundice: an unusual initial manifestation of intra-abdominal non-Hodgkin lymphoma in a child.[journals.lww.com] A 6-year-old male presented with a testicular mass, hepatosplenomegaly, and a pleural effusion while undergoing maintenance chemotherapy for treatment of T-cell acute lymphoblastic[ncbi.nlm.nih.gov] There was moderate pallor, bilateral, multiple, discrete, soft cervical lymph nodes with largest measuring up to 2 cm.[henrypublishinggroups.com]

  • Autoimmune Hemolytic Anemia

    Secondary AIHA might not be diagnosed appropriately because the obstructive jaundice observed in type 1 AIP/IgG4-SC can obscure the presence of hemolytic jaundice.[ncbi.nlm.nih.gov] A 7-month-old boy, presented with prolonged fever, erythematous rash, severe pallor and hepatosplenomegaly.[ncbi.nlm.nih.gov] A 48 year old lady presented with jaundice and exertional breathlesness.[ncbi.nlm.nih.gov]

  • ALK+ Histiocytosis

    After noticing he appeared jaundiced, doctors did a blood test and discovered his platelet count was 18,000, significantly lower than the average count of 150,000.[medium.com] General pathology Genetic and developmental anomalies ALK histiocytosis See also histiocytoses ALK immunoreactivity Clinical synopsis pallor massive hepatosplenomegaly anemia[humpath.com] Other potential signs and symptoms include: weight loss, jaundice, vomiting, limping, short stature, delayed puberty, mental deterioration, headache, dizziness, seizures,[hopkinsmedicine.org]

  • Pyruvate Kinase Deficiency

    Pyruvate kinase deficiency may cause pregnancy-associated jaundice.[ncbi.nlm.nih.gov] A case of congenital pyruvate kinase deficiency manifested at antenatal ultrasound as isolated hepatosplenomegaly is reported and the differential diagnosis is discussed.[ncbi.nlm.nih.gov] Symptoms of this condition include pale skin (pallor), jaundice, a yellowing of the white of the eyes (icterus), fatigue, and recurrent gallstones.[wohproject.org]

  • Hodgkin's Disease

    […] old lady, 34 weeks primigravida was referred from the Emergency Department to the Medical Unit Khyber Teaching Hospital-MTI, Peshawar with four weeks of fever, progressive jaundice[ncbi.nlm.nih.gov] Physical examination revealed a cachectic male with pallor, with enlarged left supraclavicular Virchow's lymph node and hepatosplenomegaly.[ncbi.nlm.nih.gov] B symptoms were observed in 57.6% of the patients, hepatosplenomegaly--in 30.6%, anemia--in 27.1% and elevated serum lactat dehydrogenase (LDH)--in 41.2%.[ncbi.nlm.nih.gov]

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