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1,138 Possible Causes for Hepatosplenomegaly, Lymphadenopathy

  • Infectious Mononucleosis

    AIM: To depict the grey-scale and Doppler features of cervical lymphadenopathy due to infectious mononucleosis (IM) and to compare the findings with other benign conditions[ncbi.nlm.nih.gov] Both cases involved young adults presenting with fever, pharyngitis, lymphadenopathy, hepatosplenomegaly, and atypical lymphocytosis confirmed by serologic tests, liver biopsy[ncbi.nlm.nih.gov] Benign lymphadenopathy with extensive necrosis Any benign lymphadenopathy may at times show necrosis, either focal or extensive.[doi.org]

  • Angioimmunoblastic Lymphadenopathy

    AILD is characterized by generalized lymphadenopathy, hepatosplenomegaly, immunological abnormalities, polyclonal hypergammaglobulinemia and anemia.[ncbi.nlm.nih.gov] A 20-year-old man with ulcerative colitis was admitted because of fever, eruption and lymphadenopathy. He had started taking salazosulfapyridine one month previously.[ncbi.nlm.nih.gov] Angioimmunoblastic lymphadenopathy with disproteinemia (AILD) is a systemic lymphoproliferative disorder characterized by constitutional symptoms such as generalized lymphadenopathy, hepatosplenomegaly[ncbi.nlm.nih.gov]

  • Adult-Onset Still Disease

    Other common manifestations of AOSD are lymphadenopathy, hepatosplenomegaly, muscle aches, and pharyngitis.[symptoma.com] Adult onset Still's disease (AOSD) is a systemic inflammatory disease characterized by high-fevers, articular involvement, maculopapular rash, hepatosplenomegaly, lymphadenopathy[ncbi.nlm.nih.gov] […] genetic factors, immune dysfunction and infections Clinical features Systemic inflammatory disease manifesting with spiking fever, sore throat, arthralgia, skin rash and hepatosplenomegaly[pathologyoutlines.com]

  • Multicentric Castleman's Disease

    A 46-year-old man presented with a high-grade fever, multiple lymphadenopathies, hepatosplenomegaly and human immunodeficiency virus (HIV) seropositivity, without severe immunosuppression[ncbi.nlm.nih.gov] In this study, we examined clinical and pathologic findings of nine patients with systemic IgG4-related lymphadenopathy.[ncbi.nlm.nih.gov] We report a case of a 46-year-old woman with fever, pleural effusion, massive ascites, severe edema, hepatosplenomegaly, elevation of serum creatinine level, proteinuria,[ncbi.nlm.nih.gov]

  • Castleman Disease

    For multicentric disease: multi-region CT bilateral hilar and mediastinal lymphadenopathy centrilobular nodules diffuse abdominal lymphadenopathy hepatosplenomegaly ascites[radiopaedia.org] The remaining 6 referral cases showed morphologic features consistent with reactive lymphadenopathy.[ncbi.nlm.nih.gov] […] in the groin , neck , or armpit Unintentional loss of weight In some cases fever and weakness Easy fatigue Appetite loss or extremely poor appetite Lymph node enlargement Hepatosplenomegaly[epainassist.com]

  • Primary Immune Deficiency Disorder

    […] not absent T-cell function and normal or elevated immunoglobulins Autosomal recessive or X-linked NEMO Common and opportunistic infections, lymphopenia, lymphadenopathy, hepatosplenomegaly[merckmanuals.com] Splenomegaly and generalized lymphadenopathy are present in many patients with common variable immunodeficiency (CVID).[emedicine.medscape.com] […] reduced activity of RAG1 . [3] Mice bred from this animal exhibited major symptoms of Omenn syndrome, including having high numbers of memory-phenotype T cells, experiencing hepatosplenomegaly[emedicine.medscape.com]

  • Chronic Lymphocytic Leukemia

    III Lymphocytosis; lymphadenopathy; hepatosplenomegaly, anemia IV Lymphocytosis, lymphadenopathy; hepatosplenomegaly, thrombocytopenia anemia CHRONIC LYMPHOCYTIC LEUKEMIA[medical-dictionary.thefreedictionary.com] After 3 years, he presented a CLL progression with worsening lymphocytosis, anemia, thrombocytopenia, increased splenomegaly, and lymphadenopathies.[ncbi.nlm.nih.gov] Lymphadenopathy may or may not be present. Stage III: Absolute lymphocytosis with anemia is present. Hepatosplenomegaly and lymphadenopathy may or may not be present.[symptoma.com]

  • Juvenile Onset Stills Disease

    Appearance of rash, hepatosplenomegaly, serositis and generalized lymphadenopathy.[symptoma.com] This characteristic diagnostic triad may also be associated with an adenopathy and hepatosplenomegaly.[orpha.net] MAS is a severe, potentially life-threatening disorder, and clinically characterized by fever, hepatosplenomegaly, lymphadenopathy, neurologic dysfunction, and coagulopathy[stillsdisease.org]

  • Follicular Lymphoma

    […] examination revealed significant axillary and inguinal adenopathy (node size, 1.0 cm), and radiological examination (computed tomography scan and ultrasonography) showed hepatosplenomegaly[nature.com] The patient did not have any significant peripheral or axial lymphadenopathy, which made the diagnosis difficult in absence of histopathology.[ncbi.nlm.nih.gov] This patient was a 58 years old with generalized lymphadenopathy and Ann Arbor Stage III disease.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    The main clinical manifestations of PMF are anemia, bleeding, hepatosplenomegaly, fatigue, and fever.[ncbi.nlm.nih.gov] Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy[orpha.net] Abdominal examination reveals splenomegaly, palpable 8 cm. below the costal margin without hepatomegaly CT scans of the chest, abdomen, and pelvis reveal moderate mediastinal lymphadenopathy[targetedonc.com]

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