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549 Possible Causes for Hepatosplenomegaly, Pericardial Effusion, Serositis, Splenomegaly

  • Juvenile Onset Stills Disease

    effusions.[autoinflammatory.org] […] one of the following manifestations: skin rash (evanescent, non-fixed erythematous rash that accompanies fever spikes), generalized lymphadenopathy, hepatomegaly and/or splenomegaly[stillsdisease.org] Appearance of rash, hepatosplenomegaly, serositis and generalized lymphadenopathy.[symptoma.com] Some patients develop inflammation around the heart (pericarditis) and lungs (pleuritis), with occasional fluid accumulation around heart ( pericardial effusion ) and lungs[medicinenet.com]

  • Systemic Lupus Erythematosus

    We should also keep SLE in mind when assessing male patients with pericardial effusions.[ncbi.nlm.nih.gov] […] relapsing illness, with a variety of different presentations. [ 5 , 6 ] Symptoms and signs are often nonspecific - eg, fatigue (can be severe and debilitating), malaise, fever, splenomegaly[patient.info] ESRp, serositis, and anti-dsDNA antibodies were related to disease activity regardless of infections.[ncbi.nlm.nih.gov] […] relapsing illness, with a variety of different presentations. [ 5, 6 ] Symptoms and signs are often nonspecific - eg, fatigue (can be severe and debilitating), malaise, fever, splenomegaly[patient.info]

  • Adult-Onset Still Disease

    effusion.[blogs.nejm.org] […] clinically by high spiking fever, polyarthralgia/arthritis, a salmon-pink evanescent rash, predominantly neutrophilic leucocytosis, lymphadenopathy, liver dysfunction, and splenomegaly[ncbi.nlm.nih.gov] Other common manifestations of AOSD are lymphadenopathy, hepatosplenomegaly, muscle aches, and pharyngitis.[symptoma.com] Although less severe systemic manifestations, like serositis and pneumonitis, were observed, reversible liver involvement was common; the frequency of recurrent disease and[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    The condition may result in spinal cord compression, focal seizures, symptoms related to brain tumours, ascites, haematuria, pericardial effusion, pleural effusion, haemoptysis[patient.info] We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[ncbi.nlm.nih.gov] The main clinical manifestations of PMF are anemia, bleeding, hepatosplenomegaly, fatigue, and fever.[ncbi.nlm.nih.gov] Sclerosing extramedullary hematopoietic tumor (SEMHT) is a rare lesion and presented as retroperitoneal or serosal-based mass.[ncbi.nlm.nih.gov]

  • Chronic Myelomonocytic Leukemia

    We report a rare case of chronic myelomonocytic leukemia (CMML) with pericardial effusion.[ncbi.nlm.nih.gov] Splenomegaly is frequently seen and may be massive.[ncbi.nlm.nih.gov] Affected individuals present with monocytosis, cytopenias, and extramedullary manifestations like lymphadenopathy and hepatosplenomegaly.[symptoma.com] Serosal infiltration causing pleural or pericardial effusion is quite frequent and can be difficult to treat [ 23 ].[intechopen.com]

  • Chronic Constrictive Pericarditis

    In the conducted echocardiography, enlargement of right atrium (44 mm), right ventricle (46 mm), and left atrium (42 mm) along with mild pericardial effusion, pericardial[hindawi.com] […] syndrome of heart(pericardial pseudocirrhosis of liver) - I31.1 Polyserositis due to pericarditis - I31.1 pericardial - I31.1 Pseudocirrhosis, liver, pericardial - I31.1 Serositis[icd10coded.com] […] liver) syndrome of heart I31.1 (pericardial pseudocirrhosis of liver) Polyserositis due to pericarditis I31.1 pericardial I31.1 Pseudocirrhosis, liver, pericardial I31.1 Serositis[icd10data.com] […] by the development of a pericardial effusion about two weeks after the injury. 2. Fibrosis due to chronic irritation of the pericardium because of the needle itself.[kundoc.com]

  • Hodgkin's Disease

    Whole lung and heart irradiation was also planned due to bilateral pleural and pericardial effusions.[ncbi.nlm.nih.gov] The presenting feature common in all cases was superficial lymphadenopathy followed by hepatomegaly in 17 (20%) cases and splenomegaly in 16 (19%).[ncbi.nlm.nih.gov] Physical examination revealed a cachectic male with pallor, with enlarged left supraclavicular Virchow's lymph node and hepatosplenomegaly.[ncbi.nlm.nih.gov] Pericardial and pleural effusions developed in one patient after cycles 4 and 5 of GV, consistent with gemcitabine-induced radiation recall. There were no toxic deaths.[ncbi.nlm.nih.gov]

    Missing: Serositis
  • Amyloidosis

    effusion.[circ.ahajournals.org] PATIENT CONCERNS: We reported two cases with ApoA-1 amyloidosis, a 64-year-old man suffering from nephrotic syndrome and a 40-year-old man with nephrotic syndrome and splenomegaly[ncbi.nlm.nih.gov] Hepatosplenomegaly and adrenal insufficiency are common in the advanced stage of AA amyloidosis.[intechopen.com] Hepatomegaly is a frequent finding, 39 and although palpable splenomegaly is rare, evidence of splenic dysfunction is often apparent (table 5 ).[pmj.bmj.com]

    Missing: Serositis
  • Juvenile Seronegative Polyarthritis

    […] or Pericardial Effusion may be present Recurrent evanescent rash Faint salmon colored rash over trunk, palms and soles IV.[fpnotebook.com] Individuals with systemic arthritis may also have a skin rash or enlargement of the lymph nodes (lymphadenopathy), liver (hepatomegaly), or spleen (splenomegaly).Oligoarticular[icdlist.com] Migratory salmon colored light pink rash involving the trunk and/or extremities and hepatosplenomegaly are also frequently observed in patients with systemic onset.[radiopaedia.org] Serositis (pericarditis, pleuritis, peritonitis).[patient.info]

  • Familial Myelofibrosis

    Treatment Splenomegaly and extramedullary haemopoiesis Medical treatment remains the treatment of choice for most patients with symptomatic splenomegaly.[onlinelibrary.wiley.com] The illness presented with pallor, haemorrhagic symptoms, and hepatosplenomegaly, and the blood picture was that of pancytopenia and leucoerythroblastosis.[ncbi.nlm.nih.gov] Hepatosplenomegaly may cause irritability, feeding difficulties, loss of appetite and weight. Children may complain about abdominal pain.[symptoma.com] Etiology Exposure to chemicals such as benzene, ionizing radiation Familial / inherited forms exist Clinical features May be asymptomatic in early stages Often presents with hepatosplenomegaly[pathologyoutlines.com]

    Missing: Serositis

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