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28 Possible Causes for Hereditary Hemorrhagic Telangiectasia, Vein Disorder, Wide Pulse Pressure

  • Arteriovenous Fistula

    The physical manifestations of this would be a relatively normal systolic blood pressure with a decreased diastolic blood pressure resulting in a wide pulse pressure.[en.wikipedia.org] This disorder may appear in a manner suggesting deep vein thrombosis or arterial insufficiency of a lower extremity, but the presence of an abdominal bruit and a lower abdominal[link.springer.com] Often diagnosed in childhood, about 30% are associated with hereditary hemorrhagic telangiectasia.[ncbi.nlm.nih.gov]

  • Hereditary Hemorrhagic Telangiectasia

    Thus, the triad of a wide arterial pulse pressure, systolic murmur and liver bruit is virtually diagnostic for liver VMs with high output in patients with HHT.[doi.org] HHT is a disorder in which some blood vessels do not develop properly.[cdc.gov] Symptomatic Children with Hereditary Hemorrhagic Telangiectasia.[ncbi.nlm.nih.gov]

  • Hepatic Arteriovenous Malformation

    Arteriovenous malformation (AVM) is a vascular disorder in which arteries and veins are connected directly rather than through capillaries.[vascularcures.org] Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disorder characterized by multisystemic vascular dysplasia.[ncbi.nlm.nih.gov] An accessory RHV occurs in 52.5% of patients, two accessory hepatic veins in 12%, and an accessory vein draining the caudate lobe in 12%[21].[ghrnet.org]

  • Renal Arteriovenous Fistula

    The physical manifestations of this would be a relatively normal systolic blood pressure with a decreased diastolic blood pressure resulting in a wide pulse pressure.[en.wikipedia.org] ADQ Abductor digiti quinti ADR Acute dystonic reaction Adverse drug reaction ADRB2 beta-2 adrenergic receptor ADRD Alzheimer disease and related disorders ADRIA Doxorubicin[globalrph.com] The physical manifestations of this would be a relatively normal systolic blood pressure with a decreased diastolic blood pressure resulting in a wide (large) pulse pressure[wikidoc.org]

  • Right to Left Shunt

    ;, wide pulse pressure ( pulsus celer et altus ) Auscultatory findings: loud continuous murmur (“machinery” murmur ) ; ; best heard in the left infraclavicular region (Gibson's[amboss.com] Up to 90% of PAVMs are associated with hereditary haemorrhagic telangiectasia (HHT), a rare autosomal dominant inherited disorder [ 2 – 4 ].[erj.ersjournals.com] hemorrhagic telangiectasia (HHT).[ncbi.nlm.nih.gov]

  • Peripheral Arteriovenous Aneurysm

    The physical manifestations of this would be a relatively normal systolic blood pressure with a decreased diastolic blood pressure resulting in a wide pulse pressure.[en.wikipedia.org] […] varicose veins, spider veins, venous ulcers, venous reflux disease and cosmetic vein disorders.[veinsveinsveins.com] More than one raises the possibility of hereditary hemorrhagic telangiectasia. 12 CT CT is often the diagnostic imaging modality of choice.[radiopaedia.org]

  • Upper Gastrointestinal Bleeding

    23,24 The patient's age, systolic blood pressure, and pulse rate and the presence of comorbidities are used for scoring. 23 Patients with a score of 0 should be considered[uspharmacist.com] […] hypertension (eg, splenomegaly, dilated abdominal wall veins).[merckmanuals.com] Marple, Medical treatment of epistaxis in hereditary hemorrhagic telangiectasia: an evidence‐based review, International Forum of Allergy & Rhinology, 8, 6, (713-728), (2018[doi.org]

  • Aneurysm

    The use of indwelling needles or cannulae, particularly in patients with a wide arterial pulse pressure, can also lead to the formation of false aneurysms.[ncbi.nlm.nih.gov] […] of the blood vessels in which there is a tendency to form blood vessels that lack capillaries between an artery and vein Klinefelter syndrome – a genetic condition in men[med.virginia.edu] Hereditary hemorrhagic telangiectasia.[columbianeurology.org]

  • Congenital Absence of Ductus Arteriosus

    Peripheral pulses are bounding as the run-off into the pulmonary circulation drops the diastolic pressure and causes a wide pulse pressure.[patient.info] An accessory RHV occurs in 52.5% of patients, two accessory hepatic veins in 12%, and an accessory vein draining the caudate lobe in 12%[21].[ghrnet.org] Full-term infants with a significant PDA shunt have full or bounding peripheral pulses with a wide pulse pressure. A grade 1 to 4/6 continuous murmur is characteristic.[msdmanuals.com]

  • Lower Gastrointestinal Hemorrhage

    . 78 For bipolar coagulation use lower power, less pressure and shorter pulses than in the UGI tract—for example, Gold Probe (Boston Scientific) with ERBE VIO 10–15 W, 2 s[doi.org] […] hypertension (eg, splenomegaly, dilated abdominal wall veins).[merckmanuals.com] Gastrointestinal bleeding in patients with hereditary hemorrhagic telangiectasia. Am. J. Gastroenterol. 95, 415–418 (2000). 26. Longacre, A. V. et al.[nature.com]

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