Heterochromia Iridis: Causes & Reasons

Possible Causes for Heterochromia Iridis

iridis), white eye lashes, and wide-set inner corners of the eyes. [medicinenet.com]

Characteristics may include depigmentation of the hair and skin, congenital deafness, heterochromia iridis, medial eyebrow hyperplasia, hypertrophy of the nasal root, and [arl4.library.sk]

iridis Different colored eyes 0001100 Intellectual disability Mental deficiency Mental retardation Mental retardation, nonspecific Mental-retardation [ more ] 0001249 Long [rarediseases.info.nih.gov]

Waardenburg Syndrome Type 4B

Waardenburg syndrome is named after Petrus Johannes Waardenburg, a Dutch ophthalmologist, who noticed that heterochromia iridis often accompanied deafness. [dermnetnz.org]

This is known as heterochromia iridis. Heterochromia can exist without the presence of Waardenburg syndrome. [healthline.com]

Type I is characterized by the presence of dystopia canthorum, sensorineural hearing loss, heterochromia iridis, white forelock, hypopigmentation, and synophrys. [cureus.com]

Waardenburg Syndrome Type 4C

Heterochromia iridis MedGen UID: 98395 •Concept ID: C0423318 • Finding Heterochromia iridis is a difference in the color of the iris in the two eyes. [ncbi.nlm.nih.gov]

Waardenburg syndrome is named after Petrus Johannes Waardenburg, a Dutch ophthalmologist, who noticed that heterochromia iridis often accompanied deafness. [dermnetnz.org]

iridis Abnormality of the genitourinary system Cryptorchidism Abnormality of the integument Hypopigmented skin patches Premature graying of hair White eyebrow White eyelashes [ncbi.nlm.nih.gov]

Waardenburg Syndrome Type 2E

Waardenburg syndrome is named after Petrus Johannes Waardenburg, a Dutch ophthalmologist, who noticed that heterochromia iridis often accompanied deafness. [dermnetnz.org]

Major criteria Sensorineural deafness Iris pigmentary abnormality, such as heterochromia iridis – complete, partial, or segmental ; isohypochromia iridis; or fundus pigmentary [dermnetnz.org]

[from OMIM] Show allHide all Abnormality of the cardiovascular system Vascular dilatation Abnormality of the eye Blue irides Heterochromia iridis Hypopigmentation of the fundus [ncbi.nlm.nih.gov]

Waardenburg Syndrome Type 2A

[from OMIM] Show allHide all Abnormality of head or neck Underdeveloped nasal alae Wide nasal bridge Abnormality of the eye Heterochromia iridis Hypoplastic iris stroma Abnormality [ncbi.nlm.nih.gov]

Waardenburg syndrome is named after Petrus Johannes Waardenburg, a Dutch ophthalmologist, who noticed that heterochromia iridis often accompanied deafness. [dermnetnz.org]

The boy presented with heterochromia iridis and bilateral hearing loss, but did not show dystopia canthorum. [bmjopen.bmj.com]

Waardenburg Syndrome Type 4A

Heterochromia iridis MedGen UID: 98395 •Concept ID: C0423318 • Finding Heterochromia iridis is a difference in the color of the iris in the two eyes. [ncbi.nlm.nih.gov]

iridis Nystagmus Abnormality of the integument Hypopigmented skin patches Premature graying of hair White eyebrow White eyelashes White forelock Abnormality of the musculoskeletal [ncbi.nlm.nih.gov]

Waardenburg syndrome is named after Petrus Johannes Waardenburg, a Dutch ophthalmologist, who noticed that heterochromia iridis often accompanied deafness. [dermnetnz.org]

Waardenburg Syndrome Type 2D

Heterochromia iridis 0 EDN3 CL E G H 1908 613265 Waardenburg syndrome type 4B 613265 C2750457 OMIM 1 149 3178 131242 HP:0001100 HP:0001100 Heterochromia iridis 0 EDN3 CL [mseqdr.org]

Waardenburg syndrome is named after Petrus Johannes Waardenburg, a Dutch ophthalmologist, who noticed that heterochromia iridis often accompanied deafness. [dermnetnz.org]

Major criteria Sensorineural deafness Iris pigmentary abnormality, such as heterochromia iridis – complete, partial, or segmental ; isohypochromia iridis; or fundus pigmentary [dermnetnz.org]

Neuroblastoma

iridis (varying colors of the iris) hypertension from catecholamine production What Tests Should I Request to Confirm My Clinical Dx? [clinicaladvisor.com]

iridis: cervical, mediastinal neuroblastoma (prenatal / postnatal interruption of sympathetic tracts that mediate pigmentation of iris) Horner's syndrome (damage to sympathetic [pathologyoutlines.com]

[…] signs secretory diarrhea from production of vasoactive intestinal polypeptide (VIP), a paraneoplastic syndrome opsoclonus myoclonus ataxia, also a paraneoplastic syndrome heterochromia [clinicaladvisor.com]

Glaucoma

Primary congenital glaucoma is a rare disease that causes elevated intraocular pressure within the first three years of life. Few studies have explored the association of primary congenital glaucoma with malformation of corpus callosum. We report on a six-month-old female presenting with unilateral primary congenital[…] [ncbi.nlm.nih.gov]

Horner's Syndrome

Heterochromia iridis. License: [CC BY-SA]. Available from: [LINK] [geekymedics.com]

Von Passow’s syndrome is an association of Horner syndrome with heterochromia iridis. [whonamedit.com]

A. von Passow: Okulare Paresen im Symptomenbilde des "Status dysraphicus", zugleich ein Beitrag zur Ätiologie der Sympathikusparese (Horner-Syndrom und Heterochromia iridis [whonamedit.com]

Nail-Patella Syndrome

Full Text Content The nail-patella syndrome is an uncommon hereditary disease caused by mutations that result in a loss of function of the transcription factor LMX1B. Prevalence is estimated at 1/50,000 new-born babies. It is transmitted with an autosomal dominant inheritance pattern with complete penetrance. The[…] [revistanefrologia.com]

Fuchs Heterochromic Iridocyclitis

Most cases of heterochromia iridis are mild and do not have associated problems. What is heterochromia iridis? [medicinenet.com]

Heterochromia iridis-associated acquired Horner syndrome only occurs in children? 3. [neuro-ophthalmology.stanford.edu]

Affected people at times experience heterochromia iridis. [disabled-world.com]

Iris Disorder

Most cases of heterochromia iridis are mild and do not have associated problems. What is heterochromia iridis? [medicinenet.com]

4/8/2015 Most cases of heterochromia iridis occur sporadically in people with no family history of heterochromia iridis. [rarediseases.info.nih.gov]

There are a few well-known syndromes of which heterochromia iridis is a striking feature. [scientificamerican.com]

Klein-Waardenburg Syndrome

iridis, white eyelashes, leukoderma and sometimes cochlear deafness. [medical-dictionary.thefreedictionary.com]

It is considered as a severe form of type 1, or classic Waardenburg syndrome, characterized by sensorineural hearing loss, dystopia canthorum, and heterochromia iridis. [symptoma.com]

Examination showed a depigmented macule (6 cm Χ 6 cm) on his forearm, white forelock, heterochromia iridis, dystopia canthorum, synophrys, and sensory neural deafness. [ijdvl.com]

Congenital Iris Coloboma

[…] iridium Heterochromia Iridum Heterochromia iridum, congenital Heterochromia Iridum, Waardenburg Syndrome Iris Bicolor, Heterochromia Iridis Uniocularis (see also:Systemic [atlasophthalmology.net]

[…] and Ciliary Body Case Coloboma of the Choroid, Optic Pit Coloboma of the Iris Coloboma of the Iris and the Ciiary Body Congenital, Bilateral Bridge-Coloboma of the Iris Heterochromia [atlasophthalmology.net]

Congenital Syndromes) Aniridia, Hereditary Coloboma of the Iris and Ciliary Body Case Coloboma of the Iris and the Ciiary Body Congenital, Bilateral Bridge-Coloboma of the Iris Heterochromia [atlasophthalmology.net]

High Myopia-Sensorineural Deafness Syndrome

It consists of variable degrees of sensorineural hearing loss and pigmentary abnormalities of the skin, hair (white forelock), and eyes (heterochromia iridis). [quizlet.com]

iridis -- see above; or light blue eyes), and sensorineural deafness. [dizziness-and-balance.com]

iridis). [nature.com]

Autosomal Dominant Deafness 9

iridis (two different-colored irises or two colors in the same iris), and hearing loss, while others may only have dystopia canthorum. [entnet.org]

iridis -- see above; or light blue eyes), and sensorineural deafness. [dizziness-and-balance.com]

It consists of variable degrees of sensorineural hearing loss and pigmentary abnormalities of the skin, hair (white forelock), and eyes (heterochromia iridis). [consilieregenetica.org]

Incontinentia Pigmenti Achromians

Ocular abnormalities are common and include strabismus, aplasia / hypoplasia of the iris, and heterochromia iridis. [visualdx.com]

iridis, dacryostenosis, corneal opacities, optic atrophy, ptosis, nystagmus, myopia, and pigmentary disturbances of the fundus.2 The sole description of the ocular characteristics [healio.com]

Ophthalmic associations can be variable like strabismus, aplasia/hypoplasia of iris, heterochromia iridis, corneal opacity, hypertelorism, myopia, uveal coloboma or microphthalmos [heraldopenaccess.us]

Congenital Deafness

iridis and pigmentary retinopathy. [symptoma.com]

iridis (two different-colored irises or two colors in the same iris), and hearing loss, while others may only have dystopia canthorum. [entnet.org]

iridis -- see above; or light blue eyes), and sensorineural deafness. [dizziness-and-balance.com]

Retinohepatoendocrinologic Syndrome

 Horner's syndrome, usually associated with heterochromia iridis (less common ). 49. ecchymosis of the eyelids heterochromia iridis 50.  Pheochromocytoma:  This rare [slideshare.net]

Autosomal Dominant Deafness 28

iridis (two different-colored irises or two colors in the same iris), and hearing loss, while others may only have dystopia canthorum. [entnet.org]

It consists of variable degrees of sensorineural hearing loss and pigmentary abnormalities of the skin, hair (white forelock), and eyes (heterochromia iridis). [consilieregenetica.org]

[…] unusually wide bridge of the nose due to the inner angles of the eyes moved more sideways than they should be), white forelock (a white patch of hair in front of the head), heterochromia [entnet.org]

Congenital Deafness with Total Albinism

Heterochromia iridis was a prominent feature in 1 sibship in which both segmental iris bicolor and complete heterochromia occurred. [albinismo.it]

Waardenburg Syndrome

Waardenburg syndrome is named after Petrus Johannes Waardenburg, a Dutch ophthalmologist, who noticed that heterochromia iridis often accompanied deafness. [dermnetnz.org]

In 1951, Waardenburg defined 6 main features: (1) dystopia canthorum, (2) prominent broad nasal root, (3) synophrys, (4) white forelock, (5) heterochromia iridis, and (6) [medlink.com]

iridis (differently coloured eyes), which may be complete, partial, or segmental; isohypochromia iridis (pale blue eyes); or abnormal pigmentation of the fundus Type 2 Type [dermnetnz.org]

Congenital Horner Syndrome

iridis. [ncbi.nlm.nih.gov]

Heterochromia iridis-associated acquired Horner syndrome only occurs in children? 3. [neuro-ophthalmology.stanford.edu]

[…] syndrome, is related to heterochromia iridis and neuroblastoma. [malacards.org]

Ocular Albinism with Late-Onset Sensorineural Deafness

Heterochromia iridis was a prominent feature in 1 sibship in which both segmental iris bicolor and complete heterochromia occurred. [albinismo.it]

Waardenburg Syndrome Type 2

The boy presented with heterochromia iridis and bilateral hearing loss, but did not show dystopia canthorum. [bmjopen.bmj.com]

Ocular examination revealed heterochromia iridum in four cases and heterochromia iridis in two cases (Figs. 1A, 1B, and 1D ). [healio.com]

Waardenburg syndrome is named after Petrus Johannes Waardenburg, a Dutch ophthalmologist, who noticed that heterochromia iridis often accompanied deafness. [dermnetnz.org]

Waardenburg Syndrome Type 2C

Waardenburg syndrome is named after Petrus Johannes Waardenburg, a Dutch ophthalmologist, who noticed that heterochromia iridis often accompanied deafness. [dermnetnz.org]

iridis (differences in eye coloring) occurs in about half.[1] Progressive hearing loss has also been reported in some people with WS2.[3] WS2 may be caused by changes (mutations [rarediseases.info.nih.gov]

Heterochromia iridis MedGen UID: 98395 •Concept ID: C0423318 • Finding Asymmetry between the two irides or asymmetry between different parts of one iris. [www-ncbi-nlm-nih-gov.ezproxy.u-pec.fr]

Waardenburg Syndrome Type 2B

[from OMIM] Show allHide all Abnormality of head or neck Abnormality of the face Abnormality of the eye Heterochromia iridis Abnormality of the integument Premature graying [ncbi.nlm.nih.gov]

Affiliated tissues include eye and skin, and related phenotypes are sensorineural hearing impairment and heterochromia iridis Disease Ontology : 12 A Waardenburg's syndrome [malacards.org]

Waardenburg Syndrome Type 1

Partial or complete heterochromia iridis occurs in 21-28 percent of patients with WS [5]. Our case had all these clinical findings. [escholarship.org]

Waar·den·burg syn·drome ( văr-den-berg ), [MIM*193500, MIM*193510] disorder characterized by lateral displacement of inner canthi (dystopia canthorum), broad nasal root, heterochromia [medical-dictionary.thefreedictionary.com]

The boy presented with heterochromia iridis and bilateral hearing loss, but did not show dystopia canthorum. [bmjopen.bmj.com]

Peripheral Demyelinating Neuropathy - Central Dysmyelination - Waardenburg Syndrome - Hirschsprung Disease