High Density Lipoprotein Decreased: Causes & Reasons

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Possible Causes for High Density Lipoprotein Decreased

Lecithin Acyltransferase Deficiency

They showed a marked decrease in plasma high density lipoproteins (HDL) and a decrease in the ester ratio of plasma total cholesterol. [ncbi.nlm.nih.gov]

This is the first report of lecithin-cholesterol acyltransferase deficiency in Iran.The diagnosis was confirmed by a low high-density lipoprotein cholesterol concentration [ncbi.nlm.nih.gov]

Plasma triglycerides are normal to increased, low density lipoprotein (LDL) levels are reduced, and high-density lipoprotein (HDL) levels are markedly decreased. [ommbid.mhmedical.com]

Familial Combined Hyperlipidemia

This condition is characterized by high levels of total cholesterol and triglycerides, decreased high density lipoprotein (HDL) cholesterol concentration, high apoB concentration [symptoma.com]

Atorvastatin was significantly more effective in reducing total cholesterol, LDL cholesterol, apolipoprotein B, and non-high-density lipoprotein (HDL) cholesterol. [ncbi.nlm.nih.gov]

It is characterised by elevated levels of serum total cholesterol (TC), triglycerides (TGs), or both. 1, 2 Decreased high density lipoprotein cholesterol (HDL-C) levels are [nature.com]

Niemann-Pick Disease Type B

HDL cholesterol concentration Decreased circulating high-density lipoprotein cholesterol Decreased HDL cholesterol Low HDL-cholesterol [ more ] 0003233 Diffuse reticular [rarediseases.info.nih.gov]

On laboratory testing, there is a decrease in high-density lipoprotein (HDL)- cholesterol, elevated triglycerides, and an increase in LDL-cholesterol. [medbullets.com]

[…] of people who have these symptoms is not available through HPO Abnormal macular morphology 0001103 Autosomal recessive inheritance 0000007 Bone-marrow foam cells 0004333 Decreased [rarediseases.info.nih.gov]

Obesity

Trans fats increase low-density lipoprotein (LDL—the bad) cholesterol levels and decrease high-density lipoprotein (HDL—the good) cholesterol levels, and these effects appear [merckmanuals.com]

A low-fat diet decreases high density lipoprotein (HDL) cholesterol levels by decreasing HDL apolipoprotein transport rates. [dx.doi.org]

Each diet significantly reduced the low-density lipoprotein/high-density lipoprotein (HDL) cholesterol ratio by approximately 10% (all P r = 0.60; P r = 0.07; P = .40). [dx.doi.org]

Angina Pectoris

Statins (eg. simvastatin): these drugs decrease the amount of cholesterol in the blood and increase the percentage of good fats (HDL- high density lipoproteins). [myvmc.com]

Diabetes Mellitus

[…] simvastatin (ie, 80 mg daily). 441 Although the benefit of high-intensity statins declines among statin-naïve patients with ACS as a function of decreasing low-density lipoprotein [doi.org]

[…] of simvastatin (40 mg daily for 1 month followed by 80 mg daily) in the A to Z Trial (Aggrastat to Zocor), 439 and concerns have been raised recently about the safety of high-dose [doi.org]

Coronary Atherosclerosis

[…] treat many established atherosclerotic risk factors, including elevated blood pressure, insulin resistance and glucose intolerance, elevated triglyceride concentrations, low high-density [doi.org]

lipoprotein cholesterol (HDL-C) concentrations, and obesity. [doi.org]

Exercise in combination with weight reduction can decrease low-density lipoprotein cholesterol (LDL-C) concentrations and limit the reduction in HDL-C that often occurs with [doi.org]

Anabolic Steroid

Treatment was generally well tolerated but accompanied by significant increases in transaminases and low-density lipoprotein as well as decreases in high-density lipoprotein [doi.org]

lipoprotein (LDL) cholesterol (the "bad" cholesterol) Decreased high-density lipoprotein (HDL) cholesterol (the "good" cholesterol High blood pressure (hypertension) Heart [mayoclinic.org]

High-density lipoprotein cholesterol is not decreased if an aromatizable androgen is administered. Metabolism 1990; 39: 69–74 PubMed CrossRef Google Scholar 38. [doi.org]

Testosterone

There was also a statistically significant decrease in high-density lipoprotein levels upon initiation of testosterone therapy. [ncbi.nlm.nih.gov]

Results: Compared with placebo, testosterone treatment significantly decreased total cholesterol (adjusted mean difference, -6.1 mg/dL; P < 0.001), high-density lipoprotein [ncbi.nlm.nih.gov]

Insulin sensitivity improved but high-density lipoprotein cholesterol decreased; by the end of the study, 47.8% in the testosterone group vs 35.5% in the placebo group had [dx.doi.org]

Familial Hypercholesterolemia

Prog Lipid Res. 2017 Jul;67:16-26. doi: 10.1016/j.plipres.2017.05.001. Epub 2017 May 12. Author information 1 Department of Medical Biotechnology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. 2 Department of Medical Biotechnology, Faculty of Medicine, Mashhad University of Medical Sciences,[…] [ncbi.nlm.nih.gov]

Hypoalphalipoproteinemia

Abstract A 16-year-old boy presented with bilateral arcus cornealis and markedly decreased plasma high density lipoprotein cholesterol. [ncbi.nlm.nih.gov]

Familial Hypoalphalipoproteinemia (main mutations) FHA Signs/symptoms: Decreased high density lipoprotein (HDL) cholesterol. [diagene.ch]

Abstract Familial hypoalphalipoproteinemia (hypoalpha), characterized by a decreased high density lipoprotein level, is associated with an increased incidence of premature [ncbi.nlm.nih.gov]

Fat-Restricted Diet

Familial lecithin-cholesterol acyltransferase (LCAT) deficiency is a hereditary disease characterized by an abnormal lipid profile, corneal opacity, anemia and progressive renal disease. We report a patient with complete loss of LCAT activity due to a novel lcat gene mutation of Cys74Tyr in the lid region of LCAT[…] [ncbi.nlm.nih.gov]

17-Hydroxycorticosteroid

Abstract The circadian rhythms of excretion of sodium, potassium, calcium, magnesium, phosphorus and 17-hydroxycorticosteroid (17-ohcs) were determined in five normal subjects, in six patients with hyperthyroidism and five with hypothyroidism. Constant diets with identical 3-hourly feedings were employed, and urine[…] [ncbi.nlm.nih.gov]

Hyperlipidemia due to Hepatic Triglyceride Lipase Deficiency

These individuals also have increased amounts of molecules known as high-density lipoproteins (HDLs) and decreased amounts of molecules called low-density lipoproteins (LDL [ghr.nlm.nih.gov]

Affected people may also have increased levels of high-density lipoproteins (HDLs) and decreased levels of low-density lipoproteins (LDLs), which are two molecules that help [rarediseases.info.nih.gov]

Normally, high levels of HDL (known as "good cholesterol") and low levels of LDL (known as "bad cholesterol") are protective against an accumulation of fatty deposits on the [ghr.nlm.nih.gov]

Hyperlipoproteinemia Type 5

[…] circulating high-density lipoprotein cholesterol Decreased HDL cholesterol Low HDL-cholesterol [ more ] 0003233 Decreased LDL cholesterol concentration 0003563 Diabetes mellitus [rarediseases.info.nih.gov]

lipoprotein (VLDL) and they are decreased low density lipoprotein (/ LDL) and high density (HDL). [ivami.com]

The concentration of the very low density lipoprotein triglycerides decreased by 27–33%, the low density lipoprotein by 16–19% and the high density lipoprotein cholesterol [karger.com]

Combined Hyperlipidemia

Thus, this condition is typically characterized by concurrent elevations in total cholesterol and triglycerides with decreased high-density lipoprotein cholesterol. [ncbi.nlm.nih.gov]

High concentration of apolipoprotein A-II was associated with increased indices of atherogenic lipoproteins and high-density lipoprotein-mediated reverse cholesterol transport [ncbi.nlm.nih.gov]

There may also be a decrease in HDL (high density lipoprotein) cholesterol. Genetic testing may be done. [symptoma.com]

Hereditary Calcification of Joints and Arteries

[…] levels, and decreased high-density lipoprotein levels), hypertension, sleep apnea, obesity hypoventilation syndrome, reduced chest wall compliance, increased work of breathing [quizlet.com]

Correct answers: a, c, d Rationale: Health risks associated with obesity include cardiovascular disease (related to increased low-density lipoprotein levels, increased triglyceride [quizlet.com]

decreased total lung capacity and functional residual capacity, type 2 diabetes mellitus (i.e., hyperinsulinemia and insulin resistance), osteoarthritis, hyperuricemia, [quizlet.com]

Nandrolone

Anabolic steroids have been reported to increase low-density lipoproteins and decrease high-density lipoproteins. [drugs.com]

Metabolic/Endocrine: Decreased glucose tolerance (see PRECAUTIONS, General ), increased serum levels of low-density lipoprotein and decreased levels of high-density lipoprotein [drugs.com]

THESE CHANGES INCLUDE DECREASED HIGH-DENSITY LIPOPROTEIN AND SOMETIMES INCREASED LOW-DENSITY LIPOPROTEIN. [drugs.com]

Foreign Body in the Eye

HDL cholesterol concentration Decreased circulating high-density lipoprotein cholesterol Decreased HDL cholesterol Low HDL-cholesterol [ more ] 0003233 Delayed menarche Delayed [rarediseases.info.nih.gov]

Restlessness 0000711 Seizures Seizure 0001250 Sleep terror 0030765 Tremor Tremors 0001337 5%-29% of people have these symptoms Cerebral edema Swelling of brain 0002181 Coma 0001259 Decreased [rarediseases.info.nih.gov]

Fish-Eye Disease

A 16-year-old boy presented with bilateral arcus cornealis and markedly decreased plasma high density lipoprotein cholesterol. [ncbi.nlm.nih.gov]

Showing of 13 | 80%-99% of people have these symptoms Corneal opacity 0007957 Decreased HDL cholesterol concentration Decreased circulating high-density lipoprotein cholesterol [rarediseases.info.nih.gov]

[…] plasma levels of high density lipoprotein (HDL) cholesterol but not with an increased risk of atherosclerotic cardiovascular disease. [ncbi.nlm.nih.gov]

Arcus Juvenilis

The serum high density lipoprotein was decreased. Renal function test revealed elevated serum creatinine with significant proteinuria. [ncbi.nlm.nih.gov]

Xanthelasma: clinical indicator of decreased levels of high-density lipoprotein cholesterol. [bmj.com]

On systemic work-up, his lipid profile was deranged with increased serum total cholesterol, very low density lipoprotein, low density lipoprotein and triglyceride. [ncbi.nlm.nih.gov]

Tangier Disease

Tangier's Disease (main mutations) FHA Signs/symptoms: Decreased high density lipoprotein (HDL) cholesterol. Orange tonsils, enlarged spleen, lymph nodes, hepatomegaly. [diagene.ch]

HDL cholesterol concentration Decreased circulating high-density lipoprotein cholesterol Decreased HDL cholesterol Low HDL-cholesterol [ more ] 0003233 Distal amyotrophy [rarediseases.info.nih.gov]

Tangier disease (TD) (OMIM#205400) is a rare autosomal recessive disorder resulting from mutations in the ABCA1 gene, leading to decreased levels of plasma high-density lipoproteins [ncbi.nlm.nih.gov]

Wolman Disease

Elevated low-density lipoprotein cholesterol levels and decreased high-density lipoprotein cholesterol levels are common features, and cardiovascular disease may manifest [ncbi.nlm.nih.gov]

lipoprotein cholesterol, decreased high-density lipoprotein cholesterol and elevated serum transaminases.[3] Liver biopsy findings will generally show a bright yellow-orange [en.wikipedia.org]

[…] show anaemia and their lipid profiles are generally similar to people with more common familial hypercholesterolemia, including elevated total cholesterol, elevated low-density [en.wikipedia.org]

Citrullinemia Type 2

Restlessness 0000711 Seizures Seizure 0001250 Sleep terror 0030765 Tremor 0001337 5%-29% of people have these symptoms Cerebral edema Swelling of brain 0002181 Coma 0001259 Decreased [rarediseases.info.nih.gov]

Hyperlipoproteinemia Type 1

HDL cholesterol concentration Decreased circulating high-density lipoprotein cholesterol Decreased HDL cholesterol Low HDL-cholesterol [ more ] 0003233 Decreased LDL cholesterol [rarediseases.info.nih.gov]

Showing of 21 | Medical Terms Other Names Learn More: HPO ID 80%-99% of people have these symptoms Decreased HDL cholesterol concentration Decreased circulating high-density [rarediseases.info.nih.gov]

The untreated patients all had hypercholesterolemia and hyperglyceridemia, and, on the average, decreased concentrations of both low- and high-density lipoproteins. [annals.org]

Chronic Cadmium Poisoning

Increases in oxidized low density lipoprotein and other inflammatory and adhesion molecules with a concomitant decrease in high density lipoprotein in the individuals exposed [p.bunri-u.ac.jp]

Cholesterol Ester Storage Disease

Both patients had marked decreases in serum levels of cholesterol, triglycerides, and low-density lipoprotein-cholesterol; high-density lipoprotein-cholesterol levels increased [ncbi.nlm.nih.gov]

lipoprotein cholesterol, decreased high-density lipoprotein cholesterol and elevated serum transaminases. [3] Liver biopsy findings will generally show a bright yellow-orange [en.wikipedia.org]

(such as high density lipoproteins [HDL, "high density lipoproteins"] and the very low density lipoproteins [VLDL, "very low density lipoproteins"]). [imedpub.com]

Apolipoprotein A-I Deficiency

Decreased plasma high density lipoprotein (HDL) cholesterol levels ( 31 ]. [link.springer.com]

There were abnormally low concentrations of total and high-density lipoprotein (HDL) cholesterol, apolipoprotein (apo) B, apo A-I, and apo A-II, and the phospholipids were [ncbi.nlm.nih.gov]

BACKGROUND: Apolipoprotein (apo) A-I is the major protein constituent of plasma high density lipoproteins (HDL). [clinicaltrials.gov]

High Carbohydrate Diet

Compared with the male subjects on the wash-out diet, significantly elevated levels of high-density lipoprotein cholesterol (HDL-C) and decreased levels of apolipoprotein [ncbi.nlm.nih.gov]

The high-density-lipoprotein (HDL) concentration did not change on AE but decreased 13.9% on AHA-III (P less than 0.01). [ncbi.nlm.nih.gov]

Decreased low-/high-density lipoprotein cholesterol (LDL-C/HDL-C) was observed in all participants except the female subjects with the Leu72Leu genotype. [ncbi.nlm.nih.gov]

Hyperlipoproteinemia Type 3

Furthermore, decreased high-density lipoprotein (HDL) cholesterol is commonly seen among patients with all types of HTG. [mdpi.com]

lipoprotein cholesterol Decreased HDL cholesterol Low HDL-cholesterol [ more ] 0003233 Hypercholesterolemia Elevated serum cholesterol Elevated total cholesterol Increased [rarediseases.info.nih.gov]