High Density Lipoprotein Decreased Causes & Reasons

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High Density Lipoprotein Decreased Symptom Checker: Possible causes include Obesity. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Possible Causes

Obesity

A low-fat diet decreases high density lipoprotein (HDL) cholesterol levels by decreasing HDL apolipoprotein transport rates. [dx.doi.org]

The increase in high-density lipoprotein cholesterol concentrations and the decrease in triglyceride concentrations were greater among subjects on the low-carbohydrate diet [dx.doi.org]

[…] in platelet aggregation by 13% and a mean (SD) decrease in blood pressure by 6.5 (1.5) mm Hg. 4 Assays for serum levels of total and high-density lipoprotein cholesterol, [dx.doi.org]

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Diabetes Mellitus

[…] simvastatin (ie, 80 mg daily). 441 Although the benefit of high-intensity statins declines among statin-naïve patients with ACS as a function of decreasing low-density lipoprotein [doi.org]

[…] of simvastatin (40 mg daily for 1 month followed by 80 mg daily) in the A to Z Trial (Aggrastat to Zocor), 439 and concerns have been raised recently about the safety of high-dose [doi.org]

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Angina Pectoris

Statins (eg. simvastatin): these drugs decrease the amount of cholesterol in the blood and increase the percentage of good fats (HDL- high density lipoproteins). [myvmc.com]

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Coronary Atherosclerosis

[…] treat many established atherosclerotic risk factors, including elevated blood pressure, insulin resistance and glucose intolerance, elevated triglyceride concentrations, low high-density [doi.org]

Although there was complete linkage of LRP6 R611C and hypertension, high low-density lipoprotein (LDL), TG and a prevalence of DM2 in the index kindred, the frequency of LRP6 [doi.org]

lipoprotein cholesterol (HDL-C) concentrations, and obesity. [doi.org]

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Niemann-Pick Disease Type B

On laboratory testing, there is a decrease in high-density lipoprotein (HDL)- cholesterol, elevated triglycerides, and an increase in LDL-cholesterol. [medbullets.com]

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Familial Combined Hyperlipidemia

This condition is characterized by high levels of total cholesterol and triglycerides, decreased high density lipoprotein (HDL) cholesterol concentration, high apoB concentration [symptoma.com]

Atorvastatin was significantly more effective in reducing total cholesterol, LDL cholesterol, apolipoprotein B, and non-high-density lipoprotein (HDL) cholesterol. [ncbi.nlm.nih.gov]

It is characterised by elevated levels of serum total cholesterol (TC), triglycerides (TGs), or both. 1, 2 Decreased high density lipoprotein cholesterol (HDL-C) levels are [nature.com]

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Familial Hypercholesterolemia

PLoS One. 2017 Dec 11;12(12):e0189316. doi: 10.1371/journal.pone.0189316. eCollection 2017. Author information 1 Department of Endocrinology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China. 2 Department of Endocrinology, Linzi District People's Hospital, Zibo, China. 3 Department of Gerontology,[…] [ncbi.nlm.nih.gov]

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Lecithin Acyltransferase Deficiency

They showed a marked decrease in plasma high density lipoproteins (HDL) and a decrease in the ester ratio of plasma total cholesterol. [ncbi.nlm.nih.gov]

This is the first report of lecithin-cholesterol acyltransferase deficiency in Iran.The diagnosis was confirmed by a low high-density lipoprotein cholesterol concentration [ncbi.nlm.nih.gov]

Plasma triglycerides are normal to increased, low density lipoprotein (LDL) levels are reduced, and high-density lipoprotein (HDL) levels are markedly decreased. [ommbid.mhmedical.com]

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Acute Alcohol Intoxication

Numerous explanations, including increased high density lipoprotein (HDL) levels and a direct antithrombotic effect, have been suggested. [merckmanuals.com]

On the other hand, low to moderate levels of alcohol consumption ( 1 to 2 drinks/day) may decrease the risk of death due to cardiovascular disorders. [merckmanuals.com]

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Metabolic Syndrome

A major problem with the focus on low fat is that high-carbohydrate diets can contribute to increasing triglyceride and decreasing high-density lipoprotein (HDL) concentrations [ncbi.nlm.nih.gov]

These include hyperinsulinemia, IGT, increased plasma triglyceride concentration, and decreased high-density lipoprotein cholesterol concentration, all of which are associated [diabetes.diabetesjournals.org]

[…] in patients with hypertension and the fact that this risk if not reduced with antihypertensive treatment are due to the clustering of risk factors for CAD, in addition to high [diabetes.diabetesjournals.org]

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Menopause

[…] levels of low-density lipoprotein cholesterol. [35] Moreover, women with higher concentrations of 25OHD3 had higher levels of high-density lipoprotein cholesterol but lower [emedicine.medscape.com]

[…] triglyceride levels. [35] Raloxifene is an SERM that acts directly on estrogen receptors in the bone to decrease resorption. [emedicine.medscape.com]

Calcium/Vitamin D Trial, they found that daily supplementation with 1,000 mg of elemental calcium and 400 IU of vitamin D3 significantly increased concentrations of 25OHD3 and decreased [emedicine.medscape.com]

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Hypertension

Ramipril treatment resulted in a significant plausible modification in high-density lipoprotein (HDL) (P .0390), glucose (P .0213), and hsCRP (P .0053) concentrations [ncbi.nlm.nih.gov]

lipoprotein triglycerides; (5) decreased high-density lipoprotein cholesterol; and (6) hypertension. [doi.org]

as well as decreased SI (P .0009) value, while nebivolol treatment showed no such benefits. [ncbi.nlm.nih.gov]

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Insulin Resistance

[…] and, sometimes, a decreased low-density lipoprotein cholesterol level. 8 Insulin resistance has been found in persons with low levels of high-density lipoprotein. 9 Insulin [aafp.org]

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Tonsillitis

Statins (eg. simvastatin): these drugs decrease the amount of cholesterol in the blood and increase the percentage of good fats (HDL- high density lipoproteins). [healthengine.com.au]

lipoprotein (HDL). [emedicine.medscape.com]

[…] factors include LV hypertrophy, obesity, and elevated serum levels of homocysteine, lipoprotein (a), plasminogen activator inhibitor, fibrinogen, serum triglycerides, or low high-density [emedicine.medscape.com]

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Hyperuricemia

[…] synthesis of high-density lipoprotein. [ncbi.nlm.nih.gov]

[…] association between homocysteine and atherosclerosis include stimulating smooth muscle cell growth, reducing endothelial cell growth and endothelial cell relaxation, and decreasing [ncbi.nlm.nih.gov]

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Hypoglycemia

lipoprotein Actos linked to decreased triglycerides Convenient dosing Increased risk of heart failure Causes an average of 5–10 pounds weight gain Associated with higher [en.wikipedia.org]

Expensive Thiazolidinediones (Pioglitazone, Rosiglitazone) Reduce insulin resistance by activating PPAR-γ in fat and muscle Lower risk of hypoglycemia Slight increase in high-density [en.wikipedia.org]

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Periodontitis

Periodontitis decreases the antiatherogenic potency of high density lipoprotein. J Lipid Res. 2004; 45 : 139–147. [doi.org]

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Hypogonadism

High-density lipoprotein (HDL) cholesterol levels were also found to decrease in patients that were on oral testosterone therapy [57, 113]. [hindawi.com]

In a meta-analysis study, the high-density lipoprotein (HDL) cholesterol levels were significantly lower in the testosterone-treated group than the control group [110]. [hindawi.com]

There is some evidence that after an initial decrease, HDL cholesterol levels then return to baseline [105]. [hindawi.com]

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Polycystic Ovary Syndrome

Elevation in triglycerides, total cholesterol, and low-density lipoprotein levels, as well as decrease in high density lipoprotein level in serum of women with WHR value 0.8 [ncbi.nlm.nih.gov]

lipoprotein (LDL)-cholesterol levels and/or decreased high-density lipoprotein cholesterol (HDL-C) levels. [obgyn.ucla.edu]

[…] for future cardiovascular disease and may likewise require lifestyle management, along with oral statins and other medications to correct increased triglyceride and low-density [obgyn.ucla.edu]

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Arthritis

The Brasilia Heart Study Group indicates that changes in high-density lipoprotein (HDL) during an MI may alter the antiatherogenic function of HDL to transport lipids from [emedicine.medscape.com]

[…] arterial walls. [16] The investigators noted a simultaneous decrease in lipid transfer to HDL and in the capacity of HDL to efflux cholesterol from cells occurs in the acute [emedicine.medscape.com]

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Hypercholesterolemia

Traditionally, risk factors for cardiovascular disease in adults have included elevated levels of low-density lipoprotein (LDL), decreased levels of high-density lipoprotein [pediatricheartspecialists.com]

Plasma levels of high-density lipoprotein cholesterol were decreased, and levels of triglyceride, very low—density lipoproteins, and intermediate-density lipoproteins were [jamanetwork.com]

However, blood total cholesterol, low-density lipoprotein cholesterol, and hepatic cholesterol were elevated by the HCD compared to ND, and those concentrations were decreased [ncbi.nlm.nih.gov]

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Polyps

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Alzheimer Disease

The decreased serum high-density lipoprotein (HDL) cholesterol in diabetic rats was also reversed toward normalization after the treatment ( Murugan and Pari, 2006 ). [ncbi.nlm.nih.gov]

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Cardiac Arrhythmia

Moderate alcohol intake, increased levels of high-density lipoprotein and its subfractions, and decreased risk of myocardial infarction. [doi.org]

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Polyarticular Juvenile Idiopathic Arthritis

The primary lipoprotein risk factor was decreased high-density lipoprotein cholesterol (57%), followed by elevated levels of low-density lipoprotein cholesterol (18%), triglycerides [ncbi.nlm.nih.gov]

The male patients had decreased high-density lipoprotein cholesterol levels than the female patients (p 5 years) disease duration. [ncbi.nlm.nih.gov]

CONCLUSIONS: Dyslipoproteinemia is highly prevalent in patients with polyarticular juvenile idiopathic arthritis and is primarily related to decreased high-density lipoprotein [ncbi.nlm.nih.gov]

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Coagulation Abnormalities

lipoprotein and ApoB, as well as decreased serum high-density lipoproteins and ApoA1, has been reported in coronary artery disease. 62 Against this background, ApoA1 may [healio.com]

[…] cholesterol in peripheral tissues is carried back to the liver for excretion. 58 ApoA1 levels are reportedly higher in women than men. 61 An association of elevated serum low-density [healio.com]

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Diabetes Mellitus Type 2

(LDL‐C) ‐ despite overall increases in total LDL‐C ‐ and increases in the levels of high density lipoprotein‐cholesterol (HDL‐C). [doi.org]

In clinical studies in patients with type 2 diabetes mellitus, rosiglitazone has been associated with reductions in the levels of small dense low density lipoprotein‐cholesterol [doi.org]

Diastolic and systolic blood pressure are thought to be decreased after rosiglitazone treatment. [doi.org]

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Stroke

In 1999/2000, 2001/2002, and 2003/2004, statins were being used by 19.6%, 27.3%, and 35.9% of US adults with high low-density lipoprotein cholesterol levels, respectively [doi.org]

Moderate alcohol intake, increased levels of high-density lipoprotein and its subfractions, and decreased risk of myocardial infarction. [doi.org]

( P trend P trend 10 In addition, cross-sectional population-based surveys over the past 20 years in Minnesota revealed that 1 blood pressure decreased and awareness, treatment [doi.org]

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Combined Hyperlipidemia

Thus, this condition is typically characterized by concurrent elevations in total cholesterol and triglycerides with decreased high-density lipoprotein cholesterol. [ncbi.nlm.nih.gov]

High concentration of apolipoprotein A-II was associated with increased indices of atherogenic lipoproteins and high-density lipoprotein-mediated reverse cholesterol transport [ncbi.nlm.nih.gov]

There may also be a decrease in HDL (high density lipoprotein) cholesterol. Genetic testing may be done. [symptoma.com]

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Hypoalphalipoproteinemia

Abstract A 16-year-old boy presented with bilateral arcus cornealis and markedly decreased plasma high density lipoprotein cholesterol. [ncbi.nlm.nih.gov]

Familial Hypoalphalipoproteinemia (main mutations) FHA Signs/symptoms: Decreased high density lipoprotein (HDL) cholesterol. [diagene.ch]

Adenovirus-mediated expression of apoA-I(FIN) decreased apoA-I and high density lipoprotein cholesterol concentrations in both wild-type C57BL/6J mice and in apoA-I-deficient [ncbi.nlm.nih.gov]

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